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<![CDATA[Investigational PD-L1 x VEGF-A Bispecific Antibody Demonstrates Strong Overall Response Rate in Phase II Small Cell Lung Cancer Trial]]>
11 Sep 2025 17:43 GMT
… cell lung cancer is the most aggressive type of lung cancer with … with either paclitaxel or topotecan for patients in the … than non-small cell lung cancer. Lung cancer is the second most … Patients With Small-cell Lung Cancer in Combination With Chemotherapy. …
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First Disclosure of Global Interim Phase 2 Data for BioNTech and Bristol Myers Squibb PD-L1xVEGF-A Bispecific Antibody Pumitamig (BNT327/BMS986545) in Patients with Extensive-Stage Small Cell Lung Cancer Shows Encouraging Antitumor Activity
08 Sep 2025 15:00 GMT
… Lung Cancer in Barcelona. “Small cell lung cancer is the most aggressive type of lung cancer … -stage small cell lung cancer (Cohort 1) … plus paclitaxel, or topotecan in the second- … Lung Cancer
Small cell lung cancer (SCLC) accounts for 15% of all lung cancer …
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Ifinatamab Deruxtecan Elicits Responses in Previously Treated Extensive-Stage Small Cell Lung Cancer
08 Sep 2025 00:53 GMT
… of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer.1 … in the form of topotecan, amrubicin, or lurbinectedin, … Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer; September … with relapsed small cell lung cancer (IDeate-Lung02). Clinical …
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<![CDATA[Pumitamig Shows Positive Trend in PFS Treating Patients With ES-SCLC]]>
26 Sep 2025 20:11 GMT
… Study of Lung Cancer 2025 World Conference on Lung Cancer in Barcelona … pumitamig plus paclitaxel or topotecan in the second- … With Small-cell Lung Cancer in Combination With Chemotherapy … Study of Lung Cancer 2025 World Conference on Lung Cancer. Barcelona, …
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Non-Coding RNAs Crucial in Topotecan Cancer Response
13 Sep 2025 09:07 GMT
… challenges: drug resistance.
Topotecan, a topoisomerase I inhibitor … ovarian and small cell lung cancers, clinical outcomes are … dysregulation can drastically influence Topotecan sensitivity. By targeting … the landscape of Topotecan resistance. These pathways …
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New Tools for Lung Cancer, Harder Job for Clinicians
13 Aug 2025 18:17 GMT
… was a comparison trial to topotecan and lurbinectedin, and there … brought on by the progressive lung cancer — which sadly is an … have three available in the lung cancer arena. The benefit, side … so important in small cell [lung cancer], where relapse is almost …
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Greek Researchers Lead Breakthrough Lung Cancer Study
02 Aug 2025 00:20 GMT
… tarlatamab or chemotherapy drugs, including topotecan, lurbinectedin, or amrubicin. Results … planned for World Lung Cancer Day
Coinciding with World Lung Cancer Day on Aug … of immunotherapy in small-cell lung cancer healthcare.
Greek contribution draws …
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New Trials Advance Treatments for Lymphoma, Lung Cancer and Sarcomas
25 Jul 2025 21:47 GMT
… sarcomas and ALK-positive lung cancer. Several clinical trials have … , or cyclophosphamide plus topotecan in pediatric patients with … Evaluating Neladalkib for Lung Cancer Subset
The first … -positive non-small cell lung cancer, versus Alecensa (alectinib), a …
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Targeting Glucose Transporter 1 (GLUT1) in Cancer: Molecular Mechanisms and Nanomedicine Applications
25 Sep 2025 14:07 GMT
… glucose starvation therapy in lung cancer. Chembiochem. 2024;25 … HIF-1α, oral topotecan has demonstrated clear downregulation … -associated neutrophils promotes lung Cancer growth and resistance … glucose starvation therapy in lung cancer. Chembiochem. 2024;25 …
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OPC 2025: Key Studies Shaping Lung Cancer Therapy From ASCO 2025
21 Jun 2025 02:01 GMT
… transforming the treatment landscape for lung cancer, offering new hope for patients … with both small cell lung cancer (SCLC) and non-SCLC ( … , which included lurbinectedin (Zepzelca; Jazz), topotecan (Hycamtin; Sandoz), and amrubicin (Calsed; Nippon …