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Telomir Demonstrates Telomir-1 Reverses Epigenetic Gene Silencing of STAT1, Restoring Tumor Suppressor in Human Prostate Cancer Cells, Outperforming Chemotherapy and Rapamycin
18 Jul 2025 12:27 GMT
… delivering stronger epigenetic effects than Paclitaxel or Rapamycin in aggressive PC3 … in aggressive human prostate cancer cells-achieving greater efficacy than Paclitaxel and Rapamycin …
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Investornewsbreaks Telomir Pharmaceuticals (NASDAQ: TELO) Reports Preclinical Success Of Telomir-1 In Prostate Cancer Model
19 Mar 2025 19:46 GMT
… by approximately 50% in a prostate cancer animal model. The study demonstrated … -induced toxicity when combined with Paclitaxel. Contrary to concerns that telomere …
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Telomir Pharmaceuticals Lead Drug Candidate Inhibits Tumor Growth In Aggressive Prostate Cancer Cells, Animal Study Shows
19 Mar 2025 11:56 GMT
… by approximately 50% in a prostate cancer animal model with aggressive cancer … and mortality when combined with Paclitaxel—a widely used chemotherapy but … For Antibacterial Treatment, Tissue Regeneration
Paclitaxel and other chemotherapy agents induce …
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Prostate Cancer Bone Metastasis: Molecular Mechanisms of Tumor and Bone Microenvironment
01 Feb 2025 10:18 GMT
… prostate tumors in the bone microenvironment. Mesenchymal stem cells induce already disseminated prostate cancer … facilitating metastatic prostate tumor growth in … stem cells into prostate tumours promotes metastasis. … inhibitor, and paclitaxel in patients …
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AstraZeneca’s Truqap Redeems Itself with Phase III Prostate Cancer Win
26 Nov 2024 12:49 GMT
… de novo metastatic hormone-sensitive prostate cancer.
Data for overall survival ( … trial, which combined Truqap with paclitaxel, found no significant OS benefit … patients with metastatic castration-resistant prostate cancer (mCRPC) versus Xtandi alone. These …
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AZ's Truqap delivers phase 3 win in prostate cancer subtype after recent breast cancer miss
25 Nov 2024 17:57 GMT
… making inroads in a prostate cancer subtype.
High-level … -sensitive prostate cancer (mHSPC), a specific type of prostate cancer with … with metastatic castration-resistant prostate cancer (mCRPC) with PTEN … of Truqap and chemotherapy paclitaxel were roughly the …
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Oncternal Therapeutics Announces Updated Safety and Efficacy Data for Phase 1/2 Study of ONCT-534 for the Treatment of R/R Metastatic Castration-Resistant Prostate Cancer
22 Oct 2024 13:00 GMT
… refractory metastatic Castration-Resistant Prostate Cancer (mCRPC). Based … preclinical activity in prostate cancer models against both … in combination with paclitaxel for the treatment … with metastatic castration-resistant prostate cancer (NCT05156905), and …
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Immune and Metabolic Reprogramming Induced by Paclitaxel, Capecitabine and Eribulin in Breast Cancer: Insights into Therapeutic Targets
28 Apr 2025 17:19 GMT
… eribulin, capecitabine and paclitaxel (Figure 2A). Plasma … and phosphatidylcholines with Paclitaxel treatment (Figure 4C … eribulin, capecitabine and paclitaxel, respectively. Metabolically, … carboxylate released by prostate cancer cell inhibit T …
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Corcept Initiates Trial of Relacorilant Plus Nab-Paclitaxel and Bevacizumab in Patients With Platinum-Resistant Ovarian Cancer
07 Apr 2025 12:43 GMT
… relacorilant plus nab-paclitaxel and bevacizumab evaluating … with relacorilant and nab-paclitaxel improved patients’ progression- … two medications – nab-paclitaxel and bevacizumab – will … ’s syndrome) and prostate cancer. Relacorilant is proprietary to …
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Innovative Applications of Nucleic Acid Aptamers in Colorectal Cancer Diagnosis and Therapy: From Selection Optimization to Clinical Translation
06 Nov 2025 01:12 GMT
… and significantly improved intracellular paclitaxel uptake and anti- … metastatic lesions in a prostate‐cancer metastasis model,124 … cell-SELEX conjugated with paclitaxel for treating triple- … Li C. Suppression of prostate cancer metastasis by DPYSL3-targeted …
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