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- Microsatellites

Microsatellites Newsletter

Adagene Announces Regulatory Update on Clinical Development Plan for Muzastotug in Microsatellite Stable Colorectal Cancer Following Productive Type B (End of Phase 1) Meeting with FDA 15 Jul 2025 11:00 GMT
… mg, Q3W) in patients with microsatellite stable colorectal cancer (MSS CRC … therapy, particularly focused on Metastatic Microsatellite-stable (MSS) Colorectal Cancer (CRC …
Racial Differences Found With Metastatic Prostate Cancer Tumors 18 Jul 2025 17:44 GMT
… more likely to have high microsatellite instability (MSI)—a genomic marker … patients had higher levels of microsatellite instability and more immunotherapy targets … . AR indicates androgen receptor; MSI, microsatellite instability; OR, odds ratio; and …
Early ctDNA Changes Predict Immunotherapy Outcomes in CRC 18 Jul 2025 07:03 GMT
… with deficient mismatch repair/microsatellite instability-high (dMMR/MSI …
Biomarker Testing and Treatment Selection in Advanced Endometrial Cancer 17 Jul 2025 22:29 GMT
… 4 distinct groups (POLE hypermutated, microsatellite instability-high, p53 mutated, and …
Akeso initiates patient enrolling in phase III trial of ivonescimab for first-line treatment of advanced metastatic colorectal cancer 17 Jul 2025 07:36 GMT
… mCRC cases are classified as microsatellite stable (MSS) or proficient mismatch …
Genetic mutations in prostate cancer can differ significantly based on race, ethnicity 16 Jul 2025 23:48 GMT
… , 1.1-2.5), including microsatellite instability high status (OR = 3 …
Adjuvant Hepatic Arterial Infusion Chemotherapy Versus Transarterial Chemoembolization for Preventing Early Recurrence After Surgical Resection in Hepatocellular Carcinoma 16 Jul 2025 17:40 GMT
… AFP levels, multiple tumor nodules, microsatellite lesions, and incomplete or absent …
Analysis of Risk Factors and Development of a Predictive Model for Prognosis in Early-Stage Rectal Cancer Patients 16 Jul 2025 17:40 GMT
… adenocarcinoma. Mucinous tumors, characterized by microsatellite instability and distinct gene expression …
Why Should You Consider a Cancer Clinical Trial? 16 Jul 2025 15:52 GMT
… stage 4 colorectal cancer, called “microsatellite high,” that turned out to …
Merck, AstraZeneca Cancer Collaborator Gets Swallowed Up by Sino Biopharm 16 Jul 2025 13:13 GMT
… antibody against tumors with high microsatellite instability, both in Phase III …

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