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Mechanistic Insights into Shenzhuo Formula for Diabetic Retinopathy: Integrating UPLC-Q-TOF-MS/MS, Network Pharmacology, Single-Cell RNA Sequencing Data, and Experimental Validation
18 Jul 2025 12:58 GMT
… to identify key protein-ligand interactions, including hydrogen … analysis, and protein-ligand interaction maps were generated … Dock2: improved protein-ligand blind docking by integrating … drugs used in retinal diseases: a computational approach. Front Pharmacol …
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Multi-Target Synergy Against Acute Lung Injury: Systems Pharmacology Decoding Dahuang-Huangqin Herb Pair’s Therapeutic Mechanism
17 Jul 2025 18:58 GMT
… molecular docking simulations elucidate ligand-receptor binding affinity, prioritizing … Docking Verification
The receptor-ligand docking hypothesis states that … between Scutellaria baicalensis and pharmaceutical drugs: insights from experimental studies …
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Harnessing Organoid Platforms for Nanoparticle Drug Development
17 Jul 2025 18:58 GMT
… approaches, their utility in drug delivery offers pharmacokinetic improvements and enables tumor … in delivery and make targeted ligand functionalization possible. This allows them …
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Chronic Hepatitis B Virus Pipeline Appears Robust With 50+ Key Pharma Companies Actively Working In The Therapeutics Segment Delveinsight
17 Jul 2025 01:46 GMT
… B Virus Emerging Drugs Profile
Pradefovir: Ligand Pharmaceuticals
Pradefovir is an … Products (Phase III)
Pradefovir: Ligand Pharmaceuticals
Drug profiles in the detailed report … (Phase II)
RG6346: Dicerna Pharmaceuticals
Drug profiles in the detailed report …
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Pharmacological Mechanisms and Therapeutic Potential of Resveratrol in Rheumatoid Arthritis
16 Jul 2025 17:40 GMT
… development of disease-modifying antirheumatic drugs (DMARDs), some patients still … natural compound, Res faces inherent pharmacokinetic challenges, including low bioavailability and … receptor activator of NF-kappaB ligand in rheumatoid arthritis fibroblast- …
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Oncomatryx Secures EU Funding to Advance Antibody-Drug Conjugate Platform
16 Jul 2025 11:32 GMT
… clinical programme, OMTX705, an antibody-drug conjugate (ADC) targeting Fibroblast Activation … wish to include the radiopharma-ligand technology also to this space … acquired the Austrian company Tube Pharmaceuticals GmbH (Vienna) which worked on …
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G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway
17 Jul 2025 15:20 GMT
Chronic kidney disease (CKD) affects approximately 10% of the global population, and more than 14% of the United States population (1, 2). Within CKD, there is a disparity of greater disease prevalence among the US African American population (3). Beyond …
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“Traumome” Discovery May Transform Emergency Trauma Care
16 Jul 2025 08:58 GMT
Photo Credit: iStock.com/piola666
The discovery of a ligand peptide that could serve as a targeted molecular imaging agent for human tissue injury may transform emergency trauma care.
Researchers have identified a ligand peptide they believe could …
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Discover the Growth of Biotechnology in Virginia
15 Jul 2025 22:02 GMT
… . Other notable names include Ligand Pharmaceuticals and the Virginia BioTechnology Research … Moreover, partnerships with established pharmaceutical companies can provide both funding … to numerous companies focused on drug discovery, development, and delivery …
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Endometrial Cancer Clinical Trial Pipeline Insights: 50+ Companies Shaping Future Treatment Paradigms | DelveInsight
15 Jul 2025 17:00 GMT
… 55+ pipeline endometrial cancer drugs.
Key endometrial cancer companies … stimulants, TNF-related apoptosis-inducing ligand receptor agonists, DKK1 protein … and expansion. Other Business Pharmaceutical Consulting Services Healthcare Conference Coverage …