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Recent Advances in Antibody-Drug Conjugates and Immunotherapy Combinations for Treatment of Triple-Negative Breast Cancer
13 Jan 2026 15:26 GMT
… such as malignant melanoma, lung cancer, gastrointestinal cancers and cervical … of topoisomerase I inhibitor irinotecan, and SG monotherapy … Anthracyclines, Oxaliplatin and Irinotecan have been reported to … et al. Co-delivering irinotecan and imiquimod by pH …
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Engineered Cancer Cell Membrane-Functionalized Metal-Organic Frameworks for Irinotecan/Curcumin Codelivery in Colorectal Cancer: Enhanced Efficacy and Mitigated Toxicity
18 Nov 2025 18:45 GMT
… Materials and Methods
Materials
Irinotecan was purchased from Aladdin … breast (MCF-7), and lung cancer cells (A549) using MTT … nanoassemblies overcome defects of irinotecan and SN38: enhanced … using a custom-designed irinotecan-delivering silicasome for …
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Emerging Targets in Non-Small Cell Lung Cancer
06 Sep 2025 06:12 GMT
… cell lung cancer (NSCLC) represents approximately 85% of all lung cancer … and active metabolite of irinotecan. After binding to TROP2 … in non-small cell lung cancer: molecular mechanisms and … advanced non-small cell lung cancer. Lung Cancer. 2023;182:107291. …
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<![CDATA[Amivantamab Plus FOLFOX/FOLFIRI Demonstrates Strong, Durable Activity in mCRC]]>
12 Jan 2026 16:24 GMT
… [leucovorin (folinic acid), fluorouracil, and irinotecan] plus amivantamab or FOLFOX [folinic … scientific leadership in EGFR-driven lung cancer to evaluate the potential of …
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New Trials Advance Treatments for Lymphoma, Lung Cancer and Sarcomas
25 Jul 2025 21:47 GMT
… sarcomas and ALK-positive lung cancer. Several clinical trials … or in combination with irinotecan, irinotecan plus temozolomide, or … Evaluating Neladalkib for Lung Cancer Subset
The first … -positive non-small cell lung cancer, versus Alecensa (alectinib), …
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Predictive Value of Tumor ERCC1 Expression for Treatment Outcomes After Adjuvant Chemotherapy in Patients with Completely Resected Non-Small Cell Lung Cancer
19 Jul 2025 11:24 GMT
… Keywords: non-small cell lung cancer, postoperative adjuvant chemotherapy, … resected non-small cell lung cancer. Lung Cancer. 2008;62(1):105 … cisplatin-based concurrent chemoradiotherapy. Lung Cancer. 2010;68(2): … phase III trial of irinotecan plus S-1 versus …
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Prognostic Value of C-Reactive Protein-to-Lymphocyte Ratio in Combined Immunotherapy and Chemotherapy for Small Cell Lung Cancer
16 Jul 2025 17:40 GMT
… 20% of all lung cancers.2 Recent advancements … nab-paclitaxel, and irinotecan. Treatment continued with maintenance … with advanced small cell lung cancer. Lung Cancer. 2017;8:249– … and advanced lung cancer inflammation index (ALI). Transl Lung Cancer Res. …
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Mechanistic Exploration of Shenling Baizhu Powder in Treating Irinotecan-Associated Diarrhea: A Study Based on Network Pharmacology and Experimental Validation
03 Oct 2025 08:55 GMT
… efficacy in mitigating irinotecan-triggered intestinal inflammatory … in small cell lung cancer patients: study … irinotecan-induced delayed diarrhea in recurrent small cell lung cancer … S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier …
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Feasibility and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in Patients with Previously Immunotherapy-Treated Extensive-Stage Small Cell Lung Cancer: A Retrospective Exploratory Study
09 Jun 2025 10:12 GMT
… small cell lung cancer: a retrospective cohort study. Transl Lung Cancer Res. … the study of lung cancer--what limits limited disease? Lung Cancer. 2002;37 … irinotecan vs irinotecan or topotecan for second-line treatment of small cell lung cancer. Lung Cancer …
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RYBREVANT® (amivantamab-vmjw) longer-term results show promising and durable responses in difficult-to-treat colorectal cancer
10 Jan 2026 17:36 GMT
… EPIC trial: irinotecan plus cetuximab versus irinotecan as second … Metastatic Non-small Cell Lung Cancer (METalmark). https:… Metastatic Non-small Cell Lung Cancer (swalloWTail). https:… Metastatic Non-small Cell Lung Cancer (PolyDamas). https:…
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