-
SMARCB1 Gene Therapy Using a Novel Tumor-Targeted Nanomedicine Enhances Anti-Cancer Efficacy in a Mouse Model of Atypical Teratoid Rhabdoid Tumors
14 Jun 2024 07:40 GMT
… nanotechnology, which enables brain tumor-targeted gene delivery, … a highly aggressive and incurable pediatric brain cancer, is historically … for cancer gene therapy (ie, SGT-53 and SGT-94) … : the Canadian Paediatric Brain Tumour Consortium experience. Eur …
-
Strategies and Recent Advances on Improving Efficient Antitumor of Lenvatinib Based on Nanoparticle Delivery System
10 Jun 2024 06:21 GMT
… (TACE) and ablation. TACE and ablation have … ) and Nanostructured Lipid Carriers (NLCs) to Target Brain Tumors. … combined infrared radiation and gene therapy in hepatocellular carcinoma. … Cell Proliferation and Sensitizes Doxorubicin and Cisplatin through …
-
Nanoparticles deliver gene therapy to hard-to-reach brain tumors
23 May 2024 12:19 GMT
Nanoparticles deliver anti-cancer drugs in hard-to-reach brain tumors prevalent in children, boosting both diagnosis and treatment.
A new treatment for brain cancer uses magnetic nanoparticles engineered with a specialized coating to deliver genetic …
-
CAR T cell therapy for pediatric brain cancer warrants further study
22 May 2024 17:08 GMT
… and other recurrent high-grade central nervous system (CNS) tumors, aggressive brain cancers … .
“Brain tumors are very immunosuppressive and effective … Center for Cell and Gene Therapy and oncologist at … for Pediatric Brain Cancer and the National Institutes …
-
Locally delivered CAR T cells exhibit therapeutic activity in aggressive brain tumors
15 May 2024 01:14 GMT
… obstacle to successful brain cancer treatment is the limited … cells directly into the brain tumor and cerebrospinal fluid.
Results … Provider Network professor in gene therapy and chief of neurosurgery at … therapy for treatment of brain tumors?
Badie: We’ve …
-
The Role and Mechanism of the Histone Methyltransferase G9a in Tumors: Update
30 May 2024 09:25 GMT
… malignant brain tumor that affects children and is … tumor epigenetic and transcriptomic features, and inhibiting … and promotes the polyubiquitination and degradation of methyltransferases and … for instance, via gene therapy because histone methyltransferases …
-
Gene Therapy Is Halting Cancer. Can It Work Against Brain Tumors?
22 Apr 2024 07:44 GMT
… the most common and deadly adult brain tumor.
This new more … stem cell and gene therapy research for incurable diseases and disorders through … during 30 years of brain tumor research.
The CIRM- … hasn’t worked against brain tumors. Glioblastoma cells are more …
-
Brain Targeting Nanomedicines: Pitfalls and Promise
27 May 2024 09:16 GMT
…
Nanomedicine in Brain Cancer
Brain cancers and tumors are another … brain tumors.
To target both the BBB and blood-brain tumor … and blood–tumour barrier in brain tumours and metastases … Novel focused ultrasound gene therapy approach noninvasively restores …
-
Understanding Gene Involvement in Hepatocellular Carcinoma: Implications for Gene Therapy and Personalized Medicine
07 May 2024 13:34 GMT
… with gene therapy for HCC.
Opportunities for HCC Gene Therapy
There … Wang et al combined gene therapy and thermal therapy of HCC … of endeavor, and that personalized medicine and gene therapy will shape … Westermark B. Induction of brain tumors in mice using a …
-
Denovo Biopharma’s glioma gene therapy trial receives CIRM grant
01 May 2024 10:58 GMT
… IIa clinical trial of its gene therapy, DB107, to treat … ), a deadly form of brain cancer.
The trial will assess … amiretrorepvec) as prodrug activator gene therapy and DB107-FC (extended-release 5 … our biomarker–guided DB107 gene therapy in patients with HGG …