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US FDA approves Eli Lilly's Inluriyo for adults with ER+, HER2─, ESR1─mutated advanced or metastatic breast cancer
27 Sep 2025 09:32 GMT
… MBC. Some breast cancers develop ESR1 mutations … breast cancer whose disease has recurred or progressed during or following an aromatase inhibitor … treatment in early breast cancer, including: NCT04975308 … of breast cancer diagnosed in 2024. Breast cancer …
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<![CDATA[FDA Approves Inluriyo for ESR1-Mutated Advanced Breast Cancer Based on Phase III EMBER-3 Trial Data]]>
27 Sep 2025 00:47 GMT
… ESR1-mutated advanced or metastatic breast cancer (MBC) whose disease progressed … metastatic breast cancer whose disease recurred or progressed after aromatase inhibitor therapy … With ER+, HER2- Advanced Breast Cancer (EMBER-3). ClinicalTrials.gov. …
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What you need to know about breast cancer
26 Sep 2025 22:26 GMT
… precise cause of most breast cancers is unknown. Researchers … breast cancer include:
Increasing age: The risk of breast cancer … breast cancer than men.
A family history of breast cancer, … estrogen receptor modulators and aromatase inhibitors, may be used. …
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Lilly brings second oral SERD to market for breast cancer
26 Sep 2025 15:44 GMT
… breast cancer will develop an ESR1 mutation after first-line treatment with aromatase inhibitor … to endocrine therapy with aromatase inhibitor exemestane or injectable SERD … welcomed by the Living Beyond Breast Cancer organisation for offering patients …
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Lilly’s Oral SERD Wins FDA Go-Ahead for Breast Cancer
26 Sep 2025 12:58 GMT
… patients with certain types of breast cancer.
Inluriyo is indicated for adult … HER2-negative advanced or metastatic breast cancer, who also carry ESR1 mutations … progressed after treatment with an aromatase inhibitor. Participants were randomized to receive …
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Eli Lilly Inluriyo gets USFDA nod for adults with advanced breast cancer
26 Sep 2025 10:14 GMT
… –), ESR1-mutated advanced or metastatic breast cancer (MBC) whose disease progressed after … +, HER2–, ESR1-mutated MBC. Some breast cancers develop ESR1 mutations that can … MBC following recurrence on adjuvant aromatase inhibitor (AI), +/- prior CDK4 …
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Eli Lilly's oral SERD Inluriyo passes muster with FDA in breast cancer
26 Sep 2025 01:43 GMT
… -positive, HER2-negative advanced breast cancer that carries ESR1 gene mutations … patients with ESR1-mutated [metastatic breast cancer], a mutation found in … positive, HER2-negative breast cancer following progression on an aromatase inhibitor.
While the …
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FDA approves imlunestrant for certain adults with breast cancer
26 Sep 2025 00:26 GMT
… treatment of certain adults with breast cancer who experience disease progression … of certain adults with breast cancer who experience disease progression … or metastatic breast cancer who previously received treatment with an aromatase inhibitor alone …
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<![CDATA[FDA Approves Inluriyo for ER+, HER2– Metastatic Breast Cancer]]>
26 Sep 2025 00:21 GMT
… their cancer returned following adjuvant aromatase inhibitor (AI) therapy, with … , ESR1-mutated metastatic breast cancer. Some breast cancers develop ESR1 mutations that … breast cancer whose disease returned or progressed during or after aromatase inhibitor …
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<![CDATA[FDA Approves Imlunestrant Tablets for ER+, HER2–, ESR1-Mutated Advanced or Metastatic Breast Cancer]]>
26 Sep 2025 00:20 GMT
… mutated advanced or metastatic breast cancer (MBC) whose disease … therapy with an aromatase inhibitor with or without … ] expands the metastatic breast cancer treatment landscape for patients … ER+, HER2- Advanced Breast Cancer (EMBER-3). ClinicalTrials. …