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<![CDATA[FDA Approves Rucaparib for the Treatment of Adults With mCRPC]]>
18 Dec 2025 03:03 GMT
The FDA has approved rucaparib (Rubraca; Pharmaand GmbH) for the treatment of … TRITON3 trial were published in The New England Journal of Medicine.1 … Pharma, Pfizer], abiraterone acetate [Zytiga; Janssen Biotech]), or docetaxel. Randomization was stratified …
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<![CDATA[FDA Grants Full Approval to Rucaparib for BRCA Mutation–Associated mCRPC]]>
17 Dec 2025 22:41 GMT
… randomized, phase 3 trial included patients with … such as abiraterone acetate (Zytiga) or enzalutamide (Xtandi; …
The most frequent treatment-emergent adverse effects ( … 47;www.fda.gov/drugs/;resources-information-approved-drugs/fda-grants-accelerated …
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<![CDATA[FDA Grants Regular Approval to Rucaparib for BRCA-Mutated mCRPC]]>
17 Dec 2025 21:41 GMT
The FDA has granted regular approval to rucaparib (Rubraca) for the treatment of … multicenter, open-label, randomized TRITON3 trial served as the confirmatory study … pathway inhibitor (such as abiraterone [Zytiga], enzalutamide [Xtandi], or apalutamide [ …
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J&J positions its PARP combo Akeega in new prostate cancer subset with 2nd FDA nod
16 Dec 2025 00:48 GMT
… treatment with a fresh FDA approval, making it the first precision medicine … androgen-directed prostate cancer med Zytiga (abiraterone acetate) and the … J&J’s Amplitude trial is an ongoing phase 3 … wider struggles of the PARP drug class to extend beyond …
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<![CDATA[Sequencing vs upfront intensification in metastatic prostate cancer]]>
17 Dec 2025 19:05 GMT
… apalutamide (Erleada), abiraterone acetate (Zytiga), and darolutamide (Nubeqa), were … , making safety profiles, drug interactions, and patient-specific … medical oncologists, and other specialists was identified as increasingly important as treatment …
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<![CDATA[Alexandra Sokolova, MD, outlines TRIPLE-SWITCH trial in mCSPC]]>
08 Dec 2025 20:16 GMT
… an assistant professor of medicine in the division of … of the TRIPLE-SWITCH trial, a phase 3 … multiple trials—including TITAN (apalutamide [Erleada]), LATITUDE (abiraterone acetate [Zytiga]), … , Sokolova argues that treatment intensification is warranted before …
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<![CDATA[Clinical strategies for treating metastatic castration-sensitive prostate cancer]]>
17 Dec 2025 01:29 GMT
… The conversation centered on treatment intensification, patient selection, … (Erleada), abiraterone acetate (Zytiga), and darolutamide (Nubeqa) … by robust clinical trial data and increasingly … concerns, cardiovascular health, medication burden, and patient …
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<![CDATA[First Assist: Advancing Radiation Strategies in High-Risk and Advanced Prostate Cancer, with Pretesh Patel, MD]]>
16 Dec 2025 20:02 GMT
… disease, Patel focuses on treatment intensification, post-prostatectomy management … ), and abiraterone acetate (Zytiga)—for very high-risk … to closer collaboration with medical oncology and more frequent … setting, where recent trials have reshaped the adjuvant …
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J&J’s $3B Halda Acquisition Brings a Way to Overcome Drug Resistance in Prostate Cancer & More
18 Nov 2025 00:51 GMT
… Arvinas Therapeutics, a biotech company developing drugs based on a … pairs the active pharmaceutical ingredient in Zytiga with niraparib, a … executive vice president, innovative medicine, R&D at … longer respond to standard treatments using a novel mechanism …
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Real-World Treatment Patterns and Overall Survival (OS) of Patients with Metastatic Castration-Resistant Prostate Cancer in Italy
11 Nov 2025 00:02 GMT
… data; pharmaceuticals database, for information on drug prescriptions, … -reported data stating that 42% … indicazioni terapeutiche del medicinale per uso umano «Zytiga» (abiraterone acetato … cancer treatment: a review of literature and ongoing trials. Discov …