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FDA to phase out animal testing with AI and lab-based models
11 Apr 2025 13:41 GMT
… previously studied drugs without repeating animal trials. While … drug evaluation” that could accelerate access to treatments … the scientific community. Medical sciences professional Paniz … testing MSD’s FDA-approved therapy Zolinza (vorinostat).
In …
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Epigenetic drugs show 375% increase in Series A venture financing in 2024
25 Sep 2024 16:53 GMT
… oncology. The FDA’s approval of Vertex Pharmaceuticals’ Casgevy ( … 2022, California-based Epicrispr Biotechnologies launched with $55m … drugs play a key part in precision medicine by providing tailored treatments … trials to enable the success of this drug …
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New Trial Shows a Cure for HIV May be Possible
20 Feb 2024 15:20 GMT
The cancer drug Zolinza (vorinostat) along with an … been shown in a small trial to bring HIV-infected cells … (UNC) School of Medicine, treated nine patients with Zolinza, which is used … induce cell death. Zolinza is a Merck drug first approved in 2006 …
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What to know about leukemia medication
28 Feb 2023 18:43 GMT
… cells. Examples include:
vorinostat (Zolinza)
romidepsin (Istodax)
Corticosteroids
Corticosteroids … chronic myeloid leukemia.
Leukemia medications aim to destroy cancer cells … or immunotherapy drugs.
Doctors will decide the best course of treatment based on …
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Cygnal Therapeutics Expands Leadership Team with Appointment of John A. Wagner, M.D., Ph.D., as Chief Medical Officer
16 Sep 2020 13:16 GMT
… of experience in drug research and development, translational medicine, clinical pharmacology, … numerous drugs across multiple therapeutic areas, including Januvia (sitagliptin) and Zolinza ( … board of directors of Stargazer Pharmaceuticals, is the editor-in- …
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Pre-existing anticancer drug could help treat common form of heart failure
29 Jan 2020 22:45 GMT
… School of Medicine at Temple University (LKSOM), however, a drug capable … that a drug already approved for the treatment of some … there are currently no FDA-approved therapies available for the … the name Zolinza, is currently approved for the treatment of a …
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Flagship’s Omega Aims to Take Epigenetic Drugs a Step Further
23 Sep 2019 11:57 GMT
… transformative,” says Checkmate Pharmaceuticals founder and chief scientific … cancers, with epigenetic drugs like vorinostat (Zolinza), decitabine (Dacogen), … . It is developing medicines for the rare disease … 39;s Deputy Editor, Biotechnology. You can e-mail …
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miRagen Therapeutics to Present New Cobomarsen Clinical Trial Data for Adult T-Cell Leukemia/Lymphoma and Cutaneous T-Cell Lymphoma at the 11th Annual T-Cell Lymphoma Forum
20 Dec 2018 12:00 GMT
… an active control comparison trial versus ZOLINZA (vorinostat). Based … product candidate for the treatment of pathological fibrosis, remlarsen … miRagen’s translational medicine strategy is to … For information on clinical trials please visit www.clinicaltrials …
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Trial data suggest Abivax’ drug may clear latent HIV
05 Jul 2018 10:22 GMT
… from the infection.
Various trials of aggressive antiretroviral therapy ( … despite enormous advances in drug treatment people with HIV are … of Pittsburgh School of Medicine, who is chair of … using Merck’s HDAC inhibitor Zolinza (vorinostat) so that they …
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Weekly Drug News Round-Up: August 8, 2018
09 Aug 2018 09:51 GMT
… the skin. In a trial of 332 patients, … to patients taking vorinostat (Zolinza) at a median of … Demonstrating Effectiveness of Drugs for Medication-Assisted Treatment.” New clinical endpoints … vaccine records with your doctor. All states require vaccinations …