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Xalkori Newsletter
  • Array of Agents Allow for Treatment Individualization in ROS1+ NSCLC 27 Jul 2025 14:46 GMT

    … of crizotinib (Xalkori), later generations of drugs in the realm … associate professor of clinical medicine at the University of Southern … the other agents. Treatment with the drug does not lead to … more trials [that are similar to] the [phase 3] FLAURA2 trial

  • Pledging ‘Radical Transparency,’ FDA Reveals Drug Rejection Letters — With Limits 13 Jul 2025 18:50 GMT

    … established ROS1 inhibitors Xalkori from Pfizer and … vaccine as mNEXSPIKE. In the key clinical trialFDA approved KalVista Pharmaceuticals’ Ekterly, making the pill the first oral on-demand treatment … a drug that the biotech had developed as a treatment for …

  • Navigating the Treatment Landscape in Non–Clear Cell Renal Cell Carcinoma 23 Jun 2025 14:42 GMT

    … features, biologies, and treatment responses. nccRCC histologies … from RCC clinical trials, which mainly enrolled … investigator-initiated randomized trial, patients with untreated … inhibitors cabozantinib, crizotinib (Xalkori), or savolitinib (Orpathys …

  • Chasing rivals, Nuvalent to seek approval of targeted lung cancer drug 24 Jun 2025 17:19 GMT

    … similar medicines, according to results from a clinical trial … expansion” for the drug. A similar medicine from Nuvation Bio … drugs are available for these cancers, among them Pfizer’s Xalkori … sluggish uptake of existing treatments reflects issues like …

  • Trump to sign executive order to reduce cost of prescription drugs and pharmaceuticals up to 80% 12 May 2025 02:18 GMT

    … wrote. 'The Pharmaceutical/Drug Companies would say, … Xeljanz, a treatment for autoimmune diseases including … Xalkori.  Drugmakers hiked up the prices of more than 770 drugs in 2024 alone — including medications … seen by a doctor. With insurance, copays …

  • Real-World Lung Cancer Data Links Biomarker Status to Survival and Medication Costs 19 Jun 2025 21:02 GMT

    … stage. Newer treatments like targeted therapies (such as Tagrisso, Xalkori, and others … estimates were based primarily on Medicare reimbursement rates and supplemented with … develop cheaper or more effective medications for these patients,” the authors …

  • Breaking Down Taletrectinib’s FDA Approval: Jorge J. Nieva, MD 21 Jun 2025 01:54 GMT

    … existing therapies like crizotinib (Xalkori; Pfizer) and entrectinib … NSCLC, offering personalized treatment based on toxicity … of clinical medicine, Keck School of Medicine, and … www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves …

  • FDA clears Nuvation's first product Ibtrozi, for lung cancer 12 Jun 2025 12:58 GMT

    … the FDA approved its ROS1 inhibitor Ibtrozi as a treatment for … "major milestone" in treatment, adding that Ibtrozi (taletrectinib) … drugs in the class, like Pfizer's first-to-market Xalkoridrug has been approved on the back of two phase 3 trials

  • FDA Approves Taletrectinib in ROS1+ NSCLC 11 Jun 2025 17:43 GMT

    … received prior treatment with crizotinib (Xalkori). The TRUST-II trial enrolled patients … TRUST-I and TRUST-II trials, including those who were … in December 2024.4 FDA approves taletrectinib for ROS1 … U.S. Food and Drug Administration accepts for priority …

  • US FDA approves Nuvation Bio’s rare lung cancer drug 11 Jun 2025 21:26 GMT

    drug, taletrectinib, was based on results from two mid-stage trials … in which the drug demonstrated high response … , the company added. The drug, which is a ROS1 inhibitor … Squibb’s Augtyro, Pfizer’s Xalkori and Roche’s Rozlytrek. ( …

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