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Management of Von Hippel-Lindau Syndrome
10 Jul 2025 10:39 GMT
… . Tadross is a fourth-year medical student at the University of … Miami Miller School of Medicine. Dr. Williams is an associate … . Solitary retinal capillary hemangioma: Hereditary (von Hippel-Lindau disease) or nonhereditary? Arch Ophthalmol 2001 …
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Pembrolizumab plus axitinib shows sustained benefit vs sunitinib in ccRCC
05 Aug 2025 01:07 GMT
… ) have been published in Nature Medicine, reinforcing pembrolizumab (Keytruda) plus … to be positively linked with von Hippel-Lindau tumor suppressor gene (P = .040 … treatment. News release. Vanderbilt University Medical Center. August 1, 2025. Accessed …
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Disease Monitoring and Treatment Patterns of von Hippel-Lindau Disease-Associated Renal Cell Carcinoma in the United States.
06 May 2025 14:09 GMT
Patients with von Hippel-Lindau (VHL) disease are predisposed to … . This study evaluated disease monitoring and treatment patterns … drug use, disease monitoring procedures, and medical specialist visits in … .61]), and visited more medical specialists (1.82 [95% …
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Longitudinal Evaluation of Clear-cell Renal Cell Carcinoma in von Hippel-Lindau Disease.
28 Apr 2025 07:13 GMT
… understanding the natural history of von Hippel-Lindau (VHL) disease-associated renal cell carcinoma … of surgery, including chronic kidney disease (CKD), and mortality. Radiographic … patients, with high rates of disease progression, surgery, and metastasis …
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Belzutifan for von Hippel-Lindau disease-associated renal cell carcinoma and other neoplasms (LITESPARK-004): 50 months follow-up from a single-arm, phase 2 study.
16 Apr 2025 13:30 GMT
… belzutifan as systemic treatment for von Hippel-Lindau disease-associated renal cell carcinoma.
… of the National Institutes of Health, National Cancer Institute Center … Boston, MA, USA., Vanderbilt University Medical Center, Nashville, TN, USA., University …
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Targeting transcription factors: Emerging therapeutic paradigms
04 Aug 2025 16:44 GMT
… rheumatoid arthritis9–11.
Neurological disorders feature TFs controlling neural … approved in 2021 for von Hippel-Lindau (VHL) disease 24. This breakthrough demonstrates … combination therapies and precision medicine. Artificial intelligence is accelerating …
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Penn Medicine at the 2025 ASCO Annual Meeting
23 May 2025 08:18 GMT
… data on belzutifan for von Hippel-Lindau (VHL) disease, and Phase II clinical … Hematology-Oncology and of Medical Ethics and Health Policy, will present … Hospital, Doylestown Health, Lancaster General Health, Penn Medicine Princeton Health, and Pennsylvania …
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Merck’s Welireg granted EC approval for von Hippel-Lindau disease and kidney cancer
19 Feb 2025 12:29 GMT
… monotherapy for certain patients with von Hippel-Lindau (VHL) disease and renal cell carcinoma … in 2020 alone. The disease disproportionately affects men and approximately … recommendation from the European Medicines Agency’s human medicines committee and was …
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Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease.
14 Feb 2025 15:07 GMT
… -phenotype correlations in patients with Von Hippel-Lindau (VHL) disease.
We retrospectively studied 53 … , Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo … , Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo …
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China NMPA approves Merck's Welireg to treat adult patients with certain types of von Hippel─Lindau disease─associated tumours
23 Nov 2024 10:12 GMT
… Canada, announced that the National Medical Products Administration (NMPA) in China … and in combination with other medicines.
LITESPARK-004 is an open … and CNS hemangioblastomas.
Von Hippel-Lindau disease is a rare genetic disease that impacts an …