-
<![CDATA[Iberdomide Holds Promise in Phase 3 R/R Myeloma Trial]]>
25 Sep 2025 19:03 GMT
… degradation and developing new treatment options for patients … a novel class of medicines, called [cereblon E3 … and dexamethasone vs daratumumab, bortezomib (Velcade), and dexamethasone (DVd) … a CELMoD in clinical trials. International Myeloma Foundation. …
-
<![CDATA[New Drug Combo Shows Deeper Responses in Multiple Myeloma]]>
25 Sep 2025 16:12 GMT
… from the phase 3 trial EXCALIBER-RRMM which … and dexamethasone or Darzalex, Velcade (bortezomib) and dexamethasone.
What are … were called immunomodulatory drugs. These medicines work by helping … clinical trials to better understand how new treatments may …
-
<![CDATA[Considering Subsequent Treatment in NDMM After Teclistamab-Based Induction]]>
24 Sep 2025 04:47 GMT
… sequencing subsequent lines of treatment for patients with newly … induction therapy in the trial, Raab emphasized using … and the Department of Medicine V at the … daratumumab] and lenalidomide [Revlimid], bortezomib [Velcade], and dexamethasone [RVd], are …
-
Bristol Myers says next-gen blood cancer drug hits goal in key study
23 Sep 2025 22:24 GMT
… tested iberdomideĀ alongside two other drugs, Darzalex and the steroid dexamethasone … widely used treatment combination: Darzalex, dexamethasone and another medicine called Velcade. The trial enrolled …
-
<![CDATA[Dara-Based Regimens Benefit Patients With NDMM Irrespective of Frailty]]>
25 Sep 2025 19:03 GMT
… ) and MAIA (NCT02252172) trials found that daratumumab (Darzalex … in the CEPHEUS trial, frailty scores at … daratumumab; Darzalex Faspro) plus bortezomib (Velcade), lenalidomide (Revlimid), and … at least 1 serious treatment-emergent adverse effect ( …
-
BMS eyes filings for myeloma 'celmod' iberdomide
24 Sep 2025 13:54 GMT
… drug iberdomide after reporting positive results in a phase 3 trial … $3.5 billion. Both drugs, acquired when BMS bought … J&J's Velcade (bortezomib), and dexamethasone (DVd), and … degradation and developing new treatment options for patients living …
-
BMS to speak with regulators on mid-stage multiple myeloma success
24 Sep 2025 12:16 GMT
… a novel class of medicines, called CELMoDs, … a US Food and Drug Administration (FDA) Advisory Committee (AdCom …
Currently, initial MM treatment includes Velcade (bortezomib), Revlimid (lenalidomide), and … deserve! The Clinical Trials Arena Excellence Awards …
-
<![CDATA[Treating Multiple Myeloma With Earlier CAR T-Cell Therapy]]>
24 Sep 2025 02:16 GMT
… , assistant professor of medicine and director of CAR … from the CARTITUDE-4 trial [NCT04181827] of ciltacabtagene … previous treatments with:
D-VRd (daratumumab [Darzalex], bortezomib [Velcade], lenalidomide … [PI] and immunomodulatory drug, and be refractory to …
-
<![CDATA[Tecvayli Plus Darzalex Shows Strong Results in Newly Diagnosed Myeloma]]>
23 Sep 2025 20:38 GMT
… and without bortezomib. Every patient across all treatment groups responded to … Johnson & Johnson Innovative Medicine, said in the news release … stem cell transplant. The trial is sponsored by the German … U.S. Food and Drug Administration in October 2022. …
-
<![CDATA[Alan's Multiple Myeloma Journey: Facing a New Diagnosis]]>
23 Sep 2025 14:10 GMT
… Medical Center, where he was intubated and started on Revlimid plus Velcade … a rare adverse effect of Velcade therapy, affecting only one-eighth … myeloma diagnosis and treatment, where patients may face multiple medical emergencies while …