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Highlighting Bispecific Use Across Multiple Myeloma Indications
06 Aug 2025 19:20 GMT
… Shebli Atrash, MD, medical oncologist at Levine Cancer … treatment. Contextualized by an estimated 70% overall response rate in trials … and dexamethasone—the MAIA trial (NCT02252172) regimen—in … lenalidomide with or without bortezomib (Velcade) for patients who …
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Karen's Story: Navigating Multiple Myeloma Treatment Lines
30 Jul 2025 19:48 GMT
… Michigan. Her initial treatment included Velcade and dexamethasone, though the … medical advice, Karen participated in numerous clinical trials, including treatment with … multiple previous treatments and clinical trial participation. The treatment has proven …
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Sanofi’s Sarclisa gains EC approval for multiple myeloma treatment
28 Jul 2025 10:53 GMT
… with a regimen of bortezomib, lenalidomide and dexamethasone ( … approval for the induction treatment of transplant-eligible … European Medicines Agency’s Committee for Medicinal Products … you deserve! The Pharmaceutical Technology Excellence Awards celebrate …
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GSK Blenrep combos approved in EU for treatment of relapsed/refractory multiple myeloma
27 Jul 2025 09:23 GMT
… myeloma in combination with bortezomib plus dexamethasone (BVd) … cell maturation antigen) antibody-drug conjugate (ADC) approved … Trials Unit, Haematology Department and Professor of Medicine … a fundamentally differentiated treatment approach for multiple …
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GSK adds EU to Blenrep checklist as FDA sets new PDUFA date
24 Jul 2025 20:38 GMT
GSK has added the European Medicines Agency to the list … -line treatment in combination with either Takeda's Velcade (bortezomib) and … in our DREAMM clinical trial programme and the option … FDA threw the company another curve ball as the Oncologic Drugs …
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FDA Extends Review of Blenrep Combinations in Multiple Myeloma
24 Jul 2025 17:16 GMT
… with Velcade (bortezomib) and dexamethasone, is being reviewed as a treatment … -8 phase 3 trials. These trials showed statistically significant … 3 phase 3 confirmatory trial failed to meet its … evidence of inflammation. Antibody drug conjugate was detected in …
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Press Release: Sanofi’s Sarclisa approved in the EU for the treatment of transplant-eligible newly diagnosed multiple myeloma
25 Jul 2025 05:00 GMT
… positive opinion by the European Medicines Agency's Committee for … combination with bortezomib, lenalidomide, and dexamethasone (VRd) for the induction treatment of … effective antibody-based drug combinations for the first-line treatment of myeloma …
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US FDA extends the review period for GSK’s Blenrep combinations to treat relapsed/refractory multiple myeloma
25 Jul 2025 05:36 GMT
… the US Food and Drug Administration (FDA) has extended the … care combinations in both trials and overall survival versus … the treatment of multiple myeloma:
• in combination with bortezomib and … New England Journal of Medicine. Updated PFS results were …
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GSK’s Comeback for Blenrep on Pause as FDA Delays Decision
24 Jul 2025 12:09 GMT
… for Blenrep. The antibody-drug conjugate was initially granted … Blenrep, when combined with bortezomib and dexamethasone, can significantly … s superiority over Takeda’s Velcade, likewise in patients who … a second-line treatment option.
The FDA doesn’t seem …
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Blenrep (belantamab mafodotin) combinations approved in EU for treatment of relapsed/refractory multiple myeloma
24 Jul 2025 16:17 GMT
… maturation antigen) antibody-drug conjugate (ADC) approved … Trials Unit, Haematology Department and Professor of Medicine … treatment of relapsed or refractory multiple myeloma:
in combination with bortezomib … in Clinical Practice. Pharmaceut Med. 2022 Jun; …