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Enhertu wins FDA approval as initial therapy for breast cancer
19 Dec 2025 10:05 GMT
… cancers, is an antibody-drug conjugate designed to deliver … 2012 for use with trastuzumab and chemotherapy in patients … metastatic breast cancer.
The FDA also cleared two companion … those receiving the standard treatment.
In the trial, tumors shrank or …
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AstraZeneca gets CDSCO nod for breast cancer drug
19 Dec 2025 06:54 GMT
… medicines at a rapid pace and marks its second antibody-drug … in India after trastuzumab deruxtecan, the drug firm said in … offers a much-needed treatment option for patients with … , potentially earlier in the treatment journey," AstraZeneca Pharma …
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Affordable access to life extending drug for people with incurable breast cancer
19 Dec 2025 05:20 GMT
…
Tucatinib, a breast cancer drug, will be listed on … ,500 per month
The drug is specifically for HER2- … the Pharmaceutical Benefits Scheme (PBS), in combination with trastuzumab and … emotional burden of accessing unfunded treatments. This decision means they …
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What's Next for Metastatic Breast Cancer Treatments? | SABCS 2025
18 Dec 2025 00:24 GMT
… SABCS shared ongoing trials testing these drugs in new ways … FDA approved a combination of drugs as a new first treatment … supporting the combination of trastuzumab deruxtecan (Enhertu) and … effective the medication is. Talk with your doctor about the …
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<![CDATA[Case 1: Sequencing Therapy in HER2 Mutant NSCLC After Immunochemotherapy and ADC Treatment]]>
17 Dec 2025 15:03 GMT
… , he transitioned to second-line trastuzumab deruxtecan at the lung-specific … review and the nuances between trial-defined versus clinically meaningful progression … selecting the next line of treatment in HER2-driven NSCLC.
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AstraZeneca’s Enhertu combination approved by FDA for HER2-positive breast cancer
17 Dec 2025 10:07 GMT
… approved by the US FDA to treat adult … Therapy designations from the FDA. It is based on … drug.
Sara Tolaney, a principal investigator for the trial, said: “Trastuzumab … deruxtecan plus pertuzumab is the only first-line treatment …
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<![CDATA[FDA Expands the Indications of 2 Tests to Identify Patients With HER2+ Breast Cancer Eligible for T-DXd ]]>
17 Dec 2025 02:01 GMT
… the phase 3 DESTINY-Breast09 trial (NCT04784715), which demonstrated that … could be eligible for treatment with trastuzumab, ado-trastuzumab emtansine (Kadcyla), or … www.fda.gov/drugs/drug-approvals-and-databases/fda-approves-fam-trastuzumab- …
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<![CDATA[PRO Data Support T-DXd Combo in HER2+ Advanced Breast Cancer]]>
20 Dec 2025 20:07 GMT
… of Medicine, Houston, Texas.
The DESTINY-Breast09 trial compared … September 2025, the FDA granted priority review to … 3 drugs.
Patient Reported Outcomes
Compared to trastuzumab, pertuzumab … + trastuzumab + pertuzumab (THP) for first-line (1L) treatment of …
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<![CDATA[Triple-Positive Breast Cancer Overview: Guide for Patients]]>
20 Dec 2025 15:57 GMT
… their care team, including medications, lifestyle adjustments, and … -targeted therapy with trastuzumab and hormone therapy is … also explore clinical trials for novel treatments.
Stage 2 … antibody-drug conjugates, are commonly used. Clinical trial enrollment …
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<![CDATA[How Modern Research Is Transforming Metastatic HER2+ Breast Cancer Care]]>
20 Dec 2025 01:16 GMT
… approved by an FDA-approved test.
In … DESTINY-Breast06 (NCT04494425) trial.
“Antibody-drug conjugate, [Enhertu] … trials.
The Full Circle With HER2-Positive Breast Cancer Treatment … Journal of Medicine.
"Trastuzumab deruxtecan versus trastuzumab emtansine …