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Antibody-Based Therapeutics in Small Cell Lung Cancer: A Narrative Review
15 Apr 2025 14:11 GMT
… only therapeutic options are topotecan, lurbinectedin (currently only … patients with small cell lung cancer. Lung Cancer. 2018;115:116– … patients with small cell lung cancer. Lung Cancer. 2020;147:237 … metastatic small cell lung cancers and patient-derived …
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Targeting DLL3 in Small Cell Lung Cancer and Other Neuroendocrine Carcinomas
16 Feb 2025 15:01 GMT
… cell lung cancer (SCLC) accounts for approximately 15% of lung cancer … , including lurbinectedin and topotecan.29 Its use is … patients with small cell lung cancer. Lung Cancer. 2020;147:237-243 … small cell lung cancer with CAR T cells. Transl Lung Cancer Res. …
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Asher Bio Announces Clinical Trial Collaboration and Supply Agreement on Etakafusp Alfa (AB248) in Combination with Bispecific T-cell Engager in Patients with Small Cell Lung Cancer
08 Jan 2025 13:10 GMT
… extensive-stage small cell lung cancer (ES-SCLC).
“ … Extensive-Stage Small-Cell Lung Cancer Treated With Atezolizumab, … topotecan as second-line treatment for patients with small-cell lung cancer … lung cancer progression after 2 lines of therapy. Lung Cancer. …
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Small cell lung cancer: Navigating the global clinical trial landscape
16 Dec 2024 15:20 GMT
… all lung cancer cases globally. Small cell lung cancer is … Globally, small cell lung cancer continues to pose a … treatment options include lurbinectedin, topotecan, or clinical trials. … cell lung cancer treatment.
Advancements in small cell lung cancer …
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GSK’s B7-H3-targeted antibody-drug conjugate, GSK’227, receives EMA Priority Medicines (PRIME) Designation in relapsed extensive-stage small-cell lung cancer
16 Dec 2024 07:18 GMT
… Extensive-stage small-cell lung cancer is associated with high … extensive-stage small-cell lung cancer (ES-SCLC). The … Advanced Small-Cell Lung Cancer (SCLC) Patients. Clin Lung Cancer. 2024 Mar; … )30676-8. PMID: 32224306.
Topotecan USP. Available at: https:…
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New Therapies Expand Options in Recurrent Small Cell Lung Cancer
14 Nov 2024 00:03 GMT
… to managing recurrent small cell lung cancer (SCLC), especially in patients who … only things we had were topotecan and irinotecan, but as of …
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Treatment of Small Cell Lung Cancer: Emerging Therapies after Decades of Stagnation
11 Nov 2024 10:42 GMT
… one in seven lung cancers, SCLC presents unique … relapsed SCLC has been topotecan, which offers modest … lung cancer community, the Bonnie J. Addario Lung Cancer Foundation (ALCF) and Lung Cancer … Lung Cancer: A National VA Database Analysis. Clin Lung Cancer. …
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New therapies lurbinectedin and tarlatamab bring hope for small cell lung cancer treatment
07 Nov 2024 05:16 GMT
… small cell lung cancer (SCLC), one of the least curable lung cancers, is about … arm.
“In small cell lung cancer, atezolizumab showed efficacy independent of … , than conventional anticancer drugs, including topotecan, belotecan, and irinotecan.
“The …
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Current Status and Future Prospects of TROP-2 ADCs in Lung Cancer Treatment
05 Nov 2024 16:00 GMT
… Characteristics of Patients with Lung Cancer
Lung cancer is a complex and … in the treatment of lung cancers, and a clinical … novel therapeutic approach in lung cancer. Lung Cancer. 2022;163:96–106 … rovalpituzumab tesirine compared with topotecan as second-line …
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Real-World Outcomes with Lurbinectedin in Second Line and Beyond for Extensive Stage Small Cell Lung Cancer in Korea
30 Oct 2024 08:51 GMT
… lung cancer (SCLC) accounts for approximately 10– 15% of all lung cancers … confirmed small cell lung cancer (SCLC) who … second-line chemotherapy regimens (topotecan, irinotecan + platinum (IP … stage small cell lung cancer. Clin Lung Cancer. 2023;24( …
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