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Obrixtamig Plus Topotecan Shows Tolerability, Efficacy in Advanced ES-SCLC
04 Jul 2025 20:15 GMT
The addition of topotecan (Hycamtin) to obrixtamig (BI … extensive-stage small cell lung cancer (ES-SCLC), according … AEs.
“Obrixtamig plus topotecan was tolerable with no … obrixtamig plus topotecan in patients with advanced small cell lung cancer (SCLC …
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OPC 2025: Key Studies Shaping Lung Cancer Therapy From ASCO 2025
21 Jun 2025 02:01 GMT
… transforming the treatment landscape for lung cancer, offering new hope for patients … with both small cell lung cancer (SCLC) and non-SCLC ( … , which included lurbinectedin (Zepzelca; Jazz), topotecan (Hycamtin; Sandoz), and amrubicin (Calsed; Nippon …
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Phase III DeLLphi-304 Trial Finds Imdelltra Significantly Extends Survival in Relapsed Small-Cell Lung Cancer
10 Jun 2025 16:07 GMT
… with relapsed small-cell lung cancer (SCLC) compared to … patients with small-cell lung cancer (SCLC) whose disease … small-cell lung cancer has been limited, with topotecan being the … in Relapsed Small Cell Lung Cancer (DeLLphi-304). ClinicalTrials.gov …
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Feasibility and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in Patients with Previously Immunotherapy-Treated Extensive-Stage Small Cell Lung Cancer: A Retrospective Exploratory Study
09 Jun 2025 10:12 GMT
… lung cancer.2 Extensive-stage small cell lung cancer … lung cancer: a retrospective cohort study. Transl Lung Cancer Res … of lung cancer--what limits limited disease? Lung Cancer. 2002 … topotecan for second-line treatment of small cell lung cancer. Lung Cancer …
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Tarlatamab Significantly Improves Survival in Patients With Small Cell Lung Cancer Post-Progression
06 Jun 2025 15:31 GMT
… 1 to either tarlatamab or topotecan, lurbinectedin, or amrubicin. … in Relapsed Small Cell Lung Cancer (DeLLphi-304). National … in Patients With Small Cell Lung Cancer (SCLC) (DeLLphi-301). … DLL3 in small cell lung cancer and other neuroendocrine carcinomas. …
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Imdelltra Shows Survival Benefit in Small Cell Lung Cancer
04 Jun 2025 03:06 GMT
… cytologically confirmed small cell lung cancer who experienced disease progression … chemotherapy comprising lurbinectedin (47 patients), topotecan (185 patients), or amrubicin … no), and intended chemotherapy (topotecan/amrubicin versus lurbinectedin).
…
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Dellphi-304 Data Reinforce Role of Tarlatamab as Second-Line SOC in Small Cell Lung Cancer
03 Jun 2025 05:19 GMT
… immunotherapies for our patients with lung cancer.”
Rudin is deputy director of … chemotherapy comprising lurbinectedin (n = 47), topotecan (n = 185), or amrubicin (n … vs no), and intended chemotherapy (topotecan/amrubicin vs lurbinectedin).
OS …
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ASCO: Roche, Jazz's Zepzelca small cell lung cancer win leaves room for improvement
23 May 2025 00:55 GMT
… ’s position in small cell lung cancer with Jazz Pharmaceuticals’ Zepzelca has … -line extensive-stage small cell lung cancer (ES-SCLC) significantly reduced patients … the physician’s choice of topotecan or irinotecan.
Jazz in-licensed …
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Obrixtamig Plus Topotecan Could Address a Second-Line Need in SCLC
12 Jun 2025 14:59 GMT
… ;refractory advanced small cell lung cancer (SCLC), according to … obrixtamig, in combination] with topotecan, a well-known chemotherapeutic … [agent], which is topotecan.
What makes obrixtamig’s … topotecan in patients (pts) with advanced small cell lung cancer …
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Lung Cancer Experts Highlight the Most Anticipated Abstracts at the 2025 ASCO Annual Meeting
15 May 2025 14:37 GMT
… other approved options are topotecan and tarlatamab. If the … neoadjuvant non–small cell lung cancer [NSCLC] setting, particularly … extensive-stage-small-cell-lung-cancer
Jazz Pharmaceuticals announces … extensive-stage small cell lung cancer. News release. Jazz …