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Target Acquired, Protein Deleted: The Next Frontier in Precision Medicine and IP Strategy
28 Apr 2025 19:15 GMT
… the furthest in clinical trials.
Examples of PROTACs … Degradation Landscape
Several biotechnology and pharmaceutical companies are actively … treatment of acute myeloid leukemia.” Journal of medicinal … et al. “From thalidomide to rational molecular glue design …
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KEYTRUDA® (pembrolizumab) as Perioperative Treatment With Standard of Care (SOC) Adjuvant Therapy Significantly Improved Event-Free Survival Compared to SOC Alone in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma
27 Apr 2025 16:10 GMT
… and Drug Administration (FDA), with a Prescription Drug User … infection. Institute medical management promptly, including … thalidomide analogue plus dexamethasone resulted in increased mortality. Treatment … the impact of pharmaceutical industry regulation and …
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Doctors Koop and Kelsey and the Age of Great Physicians
25 Apr 2025 08:19 GMT
… Oldham Kelsey, the FDA, and the Battle Against Thalidomide’
By Cheryl … have taken to curtail the drug’s distribution.
Kelsey was … century scientific revolution in the treatment of disease. At the … of pills and potions.”
Yet this postwar faith in medicine began …
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Banning Industry From FDA Adcomms Won’t ‘Move the Needle Much’ in Makary, RFK’s Fight Against COIs
21 Apr 2025 17:45 GMT
… companies regulated by the [FDA], such as pharmaceutical companies, from serving as … for the FDA. A provision in the Food and Drug Administration Modernization … to track the safety of thalidomide. As of 1967, the Anti …
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Ella was locked in a psych ward at 19 weeks pregnant, but doctors had misdiagnosed her
20 Apr 2025 19:03 GMT
… prescribed mirtazapine, an antidepressant that also has … , said a doctor had medically cleared Ella to … treatments has been stymied by the spectre of the thalidomide crisis – a drug … drug trials on pregnant women,” Kay-Smith said.
Mirtazapine – one of the drugs …
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‘Never taken seriously’: Jenny says doctors dismissed her concerns for years. Now she’s dying
17 Apr 2025 19:42 GMT
… of derisory submissions stating that medical misogyny did not … ”.
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“The way doctors ask questions is designed to … from clinical trials as a result of the thalidomide crisis … medical research.
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As a consequence, women are prescribed treatments …
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Outcomes of Pharmacist-Driven Clinical Interventions in a Medically Integrated Oncology Specialty Pharmacy Practice
15 Apr 2025 15:06 GMT
… to clinical trials in their … medication program improves identification of potential drug interactions, patient understanding of their treatment … Myers Squibb], and thalidomide [Thalomid; Celgene … Pharmaceuticals Corp; 2024. https://www.accessdata.fda …
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FDA Approves Treatment for Unresectable or Metastatic Hepatocellular Carcinoma
15 Apr 2025 21:03 GMT
… , open-label CheckMate-9DW trial. The trial evaluated the use of nivolumab … to a thalidomide analogue and dexamethasone.
Previously in 2020, FDA granted accelerated … first-line treatment.
Reference
1. BMS. US Food and Drug Administration Approves …
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FDA Approves Opdivo® Plus Yervoy® for Unresectable or Metastatic Hepatocellular Carcinoma
14 Apr 2025 15:58 GMT
… is added to a thalidomide analogue and dexamethasone, which … outside of controlled clinical trials. Please see the Important … 040 trial and has been an established second-line treatment … special offers
from American Pharmaceutical Review – all delivered right …
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Leprosy Treatment In India: How Dermatologists, Alternative Therapies, And Modern Medicine Are Changing Lives
13 Apr 2025 11:25 GMT
… corticosteroids, thalidomide or non-hormonal anti-inflammatory drugs, and … for neuropathic pain, anticonvulsants, tricyclic or neuroleptic antidepressants … medicine, anthroposophic medicine, and crenotherapy should be included in leprosy treatment …