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Navigating the Treatment Landscape in Non–Clear Cell Renal Cell Carcinoma
23 Jun 2025 14:42 GMT
… features, biologies, and treatment responses. nccRCC histologies include … excluded from RCC clinical trials, which mainly enrolled … led investigator-initiated randomized trial, patients with untreated … the EGFR inhibitor erlotinib (Tarceva) included a cohort of …
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Supportive Care Reduces AEs With MARIPOSA Regimen in EGFR+ NSCLC
16 Sep 2025 01:00 GMT
… 4 months of using treatment with an anticoagulant. … toxicities?
The COCOON trial [NCT06120140] randomly assigned … you see with erlotinib [Tarceva] or afatinib [Gilotrif], … BioMed Valley Discoveries, Blueprint Medicines, Calithera Biosciences, Genentech…
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Phase 1/2 Trial Investigating ATR-04 for EGFRi-Related Rashes in Lung Cancer
28 May 2025 22:23 GMT
… 1/2 clinical trial of ATR04-484, we … the FDA for ATR04-484 in the treatment of … rash associated with EGFR inhibitors.
Dr. Mary Spellman, chief medical … — including drugs like Erbitux (cetuximab), Vectibix (panitumumab), Tarceva (erlotinib) …
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OncLive’s FDA Approval Report: The Regulatory Rundown for May 2025
31 May 2025 02:11 GMT
… This is the first FDA-approved treatment for LGSOC, addressing a … of trials examining avutometinib plus defactinib and excitement antibody-drug … was paired with erlotinib (Tarceva), it led to a … letter to Incyte Corporation stating that it could not …
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A Pharmacist’s Guide to Lung Cancer and Its Key Treatments
23 Apr 2025 17:13 GMT
… Boehringer Ingelheim) and erlotinib (Tarceva; Genentech) target EGFR mutations, … the LUX-Lung trials and erlotinib benefiting … in the CheckMate 227 trial.10 Together, these … treatments advance, targeted therapies are shifting care toward personalized medicine …
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The Role of Radiosensitizing Drugs in Osteosarcoma Treatment: Mechanisms and Clinical Perspectives
13 Mar 2025 15:57 GMT
… Drug Trial Record Table
Table 2 Clinical Trials of Drugs … That Sensitize Osteosarcoma Radiotherapy in the Treatment … Panpan Huang), Gannan Medical University start-up … et al. FDA drug approval summary: erlotinib (Tarceva) tablets. Oncologist …
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Advancement of First-Line Treatments on EGFR-Mutated NSCLC
18 Jan 2025 00:27 GMT
… Hospitals Cleveland Medical Center; Giselle Dutcher, MD,medical oncologist at … ] is an important subcategory drug. I have had a … line treatment based on the phase 3 MARIPOSA-2 trial [ … gefitinib [Iressa] or erlotinib [Tarceva]. Gefitinib [was used] mainly …
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NSCLC Experts Ponder Best First-Line Treatment Options
18 Jan 2025 00:27 GMT
… out of recent clinical trials, particularly involving a combination … trial criteria for patients for whom they recommend the treatment … at Trinity Health IHA Medical Group; and Tarik Hadid … [added chemotherapy] to erlotinib [Tarceva] a lot back in the …
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University of Chicago Thought Process on First-line Treatment in EGFR NSCLC
18 Jan 2025 00:27 GMT
… ) trials.1-3 The panelists focused on how each treatment regimen … MD, associate professor of medicine. Additional panelists included James … gefitinib [Iressa] or erlotinib [Tarceva]. The median progression-free … trial was to look at arm A vs arm B. The FDA …
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Bevacizumab plus erlotinib is highly active in HLRCC-associated papillary renal cell carcinoma
05 Sep 2025 20:44 GMT
… (Avastin) plus erlotinib (Tarceva) elicited encouraging anti-tumor … trial (NCT01130519)published in the New England Journal of Medicine … multivariable analysis, previous treatment was shown to be … . The most common treatment-related adverse events (TRAEs …