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<![CDATA[New Directions in Treatment for Patients With GIST ]]>
30 Oct 2025 22:19 GMT
… Medical School.
Can you discuss emerging second- and third-line treatment … of a large multicenter trial looking at Sutent (sunitinib) versus IDRX … second and third line of treatment. So those are the … there are some phase 1 trials looking at the combination of …
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<![CDATA[Non–Clear Cell RCC Trials Support Regimens Approved for Clear Cell RCC]]>
28 Oct 2025 01:14 GMT
… there are now several trials have supported the use … Medicine, moderated a discussion on how to select treatment … several TKIs, including sunitinib [Sutent], cabozantinib, and lenvatinib [Lenvima … Lobins, DO: The SUNNIFORECAST trial [NCT03075423] mirrors the …
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<![CDATA[Improved Survival Observed in CABINET Trial of Pancreatic NETs]]>
17 Sep 2025 21:22 GMT
… of Internal Medicine at Mayo Clinic, discusses the CABINET trial (NCT03375320) … months set by sunitinib (Sutent), another TKI approved in … [treatment], if you will, and was approved by the FDA for … the [Alliance for Clinical Trials in Oncology]. Dr Jennifer …
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Evaluating Efficacy of Second-Line RCC Treatments Post-Immunotherapy
15 Jul 2025 13:04 GMT
… in the Department of Medical Oncology & … guidelines for second-line treatments, while emphasizing the … , pazopanib [Votrient], sunitinib [Sutent], bevacizumab [Avastin], etc, … pharmacology and drug-drug interactions of anti-angiogenic drugs. Cancer …
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Navigating the Treatment Landscape in Non–Clear Cell Renal Cell Carcinoma
23 Jun 2025 14:42 GMT
… features, biologies, and treatment responses. nccRCC histologies include … excluded from RCC clinical trials, which mainly enrolled … led investigator-initiated randomized trial, patients with untreated … TKI) monotherapy with sunitinib (Sutent). The study met its …
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Additional Treatment Options Underscore the Need for Collaboration and Mutational Testing in GIST
24 Jun 2025 21:08 GMT
… Sarcoma Unit and a medical oncologist at The Royal … , randomized phase 3 IMADGIST trial. IMADGIST evaluated maintenance imatinib … 2 randomized trials which will hopefully guide treatment in the … receive ripretinib or sunitinib [Sutent]. The primary end point …
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Dr Jones on the Evolving Treatment Landscape in GIST
20 Jun 2025 00:55 GMT
… a consultant medical oncologist, professor of medical oncology, and … in the evolving treatment landscape for patients with … recently completed trials. The phase 3 INSIGHT trial (NCT05734105) … (Qinlock) or sunitinib (Sutent), with progression-free survival …
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Inhibrx Biosciences’ stock soars on chondrosarcoma Phase II victory
24 Oct 2025 17:52 GMT
… ) over placebo.
Following treatment with ozekibart, patients’ median … face competition from Servier Pharmaceuticals’ IDH inhibitor, Tibsovo … ) master trial. This study found that Opdivo plus Sutent (sunitinib … , the biotech is now exploring the drug in other …
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FDA Approval of Cabozantinib for Pancreatic and Extra-Pancreatic Neuroendocrine Tumors Opens the Door to a New Standard Option
25 Apr 2025 19:41 GMT
… associate professor of medicine at Harvard Medical School, both … pNETs, sunitinib [Sutent] is an FDA approved option. However … pause treatment or reduce the dose. In the trial, … ;www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves- …
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RCC Treatment Decision-Making Requires a Balance of Efficacy and Individual Patient Considerations
16 Apr 2025 20:34 GMT
… biomarker could help inform treatment selection in the frontline … and director of Genitourinary Medical Oncology Research in New … ] phase 3 KEYNOTE-426 trial [NCT02853331], pembrolizumab [Keytruda] … was compared against sunitinib [Sutent] monotherapy, which was …