-
<![CDATA[FDA Review Restarts for Rivoceranib/Camrelizumab in Advanced HCC]]>
03 Feb 2026 22:45 GMT
… kinase inhibitor sorafenib (Nexavar).2 In this trial, a … treatment strategies and the European Society for Medical Oncology … FDA's next assessment of the manufacturing remediations … Therapeutics announces FDA acceptance of new drug application resubmission …
-
<![CDATA[FDA Accepts NDA for Rivoceranib and Camrelizumab in 1L Unresectable HCC]]>
02 Feb 2026 18:12 GMT
… phase 3 CARES-310 trial (NCT03764293), which compared … the combination or sorafenib monotherapy. The treatment regimen for … Therapeutics announces FDA acceptance of New Drug Application resubmission … News release. Jiangsu Hengrui Pharmaceuticals Co Ltd. May 17 …
-
Plant-Derived Exosome-Like Nanoparticles: Mechanisms of Cross-Kingdom Regulation and Perspectives as Natural Drug Carriers for Disease Treatment
02 Feb 2026 13:58 GMT
… recent years, precision biotechnologies represented by optogenetics have … facilitated oral delivery of sorafenib and improved hepatic … microRNA delivery in cancer treatment. Drug Deliv Transl Res. … for improved dermal drug delivery. Pharmaceutics. 2022;14(3 …
-
Post-Translational Modifications of Histones and Non-Histones in Liver Disease and Traditional Chinese Medicine Treatment: A Narrative Review
02 Feb 2026 13:58 GMT
… unique curative effect. Traditional Chinese medicine treatment has multi-target, multi- … development of novel targeted drugs or natural drugs.
Abbreviations
ACC, Acetyl … promotes hepatocellular carcinogenesis and sorafenib resistance by activating HDAC5‐LSD1 …
-
Recent Advances in Mitochondria-Targeted Nano-Drug Delivery Systems for Cancer Therapy
02 Feb 2026 07:56 GMT
… cells to treatments, thereby enhancing their drug resistance.6 … biological barriers to drug delivery. Nat Biotechnol. 2015;33( … E, et al. Sorafenib targets the mitochondrial electron … mitochondrial targeting and imaging. Pharmaceutics. 2022;15(1):103. …
-
HLB restarts FDA review with resubmitted liver cancer combo application
26 Jan 2026 01:17 GMT
… resubmitted a new drug application for rivoceranib, … partner Jiangsu Hengrui Pharmaceuticals resubmitted a biologics license … Bayer’s Nexavar (sorafenib) in unresectable hepatocellular carcinoma … The European Society for Medical Oncology (ESMO) living …
-
<![CDATA[Stage 4 Papillary Thyroid Cancer: A Guide to Diagnosis, Treatment and Management]]>
18 Jan 2026 19:24 GMT
… doctors use tyrosine kinase inhibitors (TKIs). Drugs like Lenvima (lenvatinib) or (Nexavar) sorafenib … a daily hormone pill, known as levothyroxine … there clinical trials available if standard treatments stop … substitute for professional medical advice, as …
-
HCC Treatment Shifts Toward Immunotherapy, but Survival Gains Remain Limited: JAMA Study Shows
12 Jan 2026 16:30 GMT
… of Medicine, Massachusetts General Hospital, Boston, examined contemporary treatment patterns … treatment patterns for hepatocellular carcinoma shifted markedly over time, with sorafenib … and prospective trials—is needed to refine treatment sequencing …
-
Extracellular Vesicles as Emerging Drug Delivery Platforms in Triple-Negative Breast Cancer: A Systematic Review
07 Jan 2026 20:31 GMT
… docetaxel (DTX),57 and sorafenib (SFB)49 frequently featured. … The treatment of breast cancer in the era of precision medicine. … for targeted drug delivery in ovarian cancer. Pharmaceutics. 2025;17 … al. Novel delivery of sorafenib by natural killer cell- …
-
<![CDATA[Frontline Sorafenib Shows Promising Outcomes in Metastatic Uveal Melanoma]]>
03 Jan 2026 17:15 GMT
… assigned to placebo switched to treatment with sorafenib following unblinding due to … argue that the [randomized discontinuation trial] design selects a more indolent … crossed over to the investigational drug after unblinding enabled an ethically …