-
Alnylam lays out $250M to equip flagship facility with cutting-edge siRNA production tech
17 Dec 2025 22:56 GMT
… opened its doors for siRNA oligonucleotide bulk drug substance active pharmaceutical … producing RNAi and other genetic medicines drug substance requires joining modified … of RNAi therapeutics, Alnylam is accelerating development of siRNA manufacturing and …
-
Advances in Microneedle Drug Delivery for Obesity: Mechanisms, Applications, and Perspectives
17 Dec 2025 15:25 GMT
… traditional delivery challenges, including genetic material instability and injection-associated … is processed by Dicer into siRNA duplexes. These duplexes associate … Applications of Microneedles in Drug Delivery and Therapeutics. Academic Press; 2024: …
-
Norgine enhances hepatology and specialty portfolio through exclusive in-licensing agreement with Vir Biotechnology
17 Dec 2025 11:05 GMT
… small interfering ribonucleic acid (siRNA) discovered by Alnylam Pharmaceuticals, Inc. … Medicines (PRIME) and orphan drug designations by the European Medicines … in-licensing-agreement-with-vir-biotechnology-302643956.html
SOURCE Norgine Pharmaceuticals …
-
The Next Chapter in Obesity Therapeutics: Vial's INHBE siRNA Draws KOL Praise as a Next-Generation Obesity Therapy
16 Dec 2025 23:58 GMT
… Vial, a clinical-stage biotech company, today announced growing … Obesity Code"
Human genetic studies have linked reduced … INHBE will discern the drug';s safety, tolerability, … next-chapter-in-obesity-therapeutics-vials-inhbe-sirna-draws-kol-praise- …
-
Silexion Therapeutics Announces Submission of Phase 2/3 Clinical Trial Application to Israel for SIL204 in Locally Advanced Pancreatic Cancer
16 Dec 2025 13:40 GMT
… the German Federal Institute for Drugs and Medical Devices (BfArM). … Silexion's next-generation siRNA therapy designed to silence mutated … Silexion Therapeutics
Silexion Therapeutics is a pioneering clinical stage, oncology-focused biotechnology company …
-
Alnylam plans $250m investment in Norton manufacturing facility, US
18 Dec 2025 09:26 GMT
… and commercial supplies of siRNA oligonucleotide drug substance for patients worldwide … of RNAi therapeutics, Alnylam is accelerating development of siRNA manufacturing and … in Integrated Manufacturing, Upperton Pharma Solutions is rapidly expanding its …
-
Nanobiotechnology Market to Hit USD 420.2 Billion by 2034, Fueled by 2025 Traffic Growth and Strategic Material & Product Innovations
17 Dec 2025 15:00 GMT
… encompasses nanotechnology and biotechnology for the development … nanoparticles to deliver drugs or genetic material accurately … amp; RNA therapy. NanoTech Pharma, BioNano Solutions, QuantumNano, … Therapeutics: Drug & RNA delivery LNPs for mRNA/siRNA, …
-
Vertero Strengthens Board of Directors with Appointment of Independent Chair R. Scott Greer
16 Dec 2025 12:30 GMT
… experience founding, growing, and advising biotech success stories makes him ideally … Chair of the Board of Sirna Therapeutics, which was sold to Merck … and held various positions at Genetics Institute, Inc., (acquired by American …
-
XOMA Royalty Enters into Agreement to Acquire Generation Bio
15 Dec 2025 22:00 GMT
… for small interfering RNA (siRNA) and other nucleic acid … licensed to pharmaceutical or biotechnology companies. When XOMA Royalty … deliver small interfering RNA (siRNA) to T cells. For … rights associated with individual drug products in development. Generation …
-
Abnormally Activated MNX1 Promotes Tumor Growth and Osimertinib Resistance and Predicts Survival in EGFR-Mutant Lung Adenocarcinoma
20 Dec 2025 08:31 GMT
… most patients experience drug resistance following oral targeted drug therapy, leading to …
Small interfering RNA (siRNA) targeting MNX1 (MNX1 siRNA-1/2 … patients’ tumors may have diverse genetic backgrounds, epigenetic modifications, and tumor …