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CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2025 Financial Results
04 Aug 2025 20:15 GMT
… anti-CD117 (c-Kit) antibody-drug conjugate (ADC), remains on track … lipoprotein(a) [Lp(a)], a genetically determined risk factor associated with … interfering ribonucleic acid (siRNA). Developed initially by Sirius Therapeutics, SRSD107 specifically targets …
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Vir Biotechnology Pivots to Cancer, Infectious Disease after Commercial and Clinical Setbacks
01 Aug 2025 01:52 GMT
… be busy for Vir Biotechnology as it strives to … small/mid-capitalization biotechnology sector with J.P. … discovered the drug, to develop and commercialize siRNA therapeutics for infectious … the best possible antibody therapeutics. So I thought that …
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Silexion Therapeutics Announces Exercise of Warrants for $1.8 Million Gross Proceeds
01 Aug 2025 00:00 GMT
… Silexion Therapeutics Silexion Therapeutics Corp is a pioneering clinical-stage, oncology-focused biotechnology … also advancing its next-generation siRNA candidate, SIL-204, designed to …
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Alnylam's Amvuttra Makes Powerful Entrance, Eyes First-Line Dominance
01 Aug 2025 18:40 GMT
… , the U.S. Food and Drug Administration on Thursday approved Amvuttra … that Alnylam is the premier siRNA therapeutics company, and with the P5x25 … and become a fully sustainable biotech growth story.”
Various analysts have …
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Aggregation of Stress Granules Induced by Hypoxia and Lipopolysaccharide via PKR-p-eIF2α Pathway and 4EBP1 Pathway Inhibits the Inflammatory Response in Peri-Implantitis
04 Aug 2025 17:54 GMT
… teeth (10 or more), drug use, smoking, previous … -labeled secondary antibodies (Biyuntian Biotechnology). The protein bands were … pathway by PKR siRNA or 4EBP1 siRNA significantly reduced … Current molecular, cellular and genetic aspects of peri-implantitis …
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Advances and Challenges in Nano-Delivery Systems for Glioblastoma Treatment: A Comprehensive Review
04 Aug 2025 11:04 GMT
… molecules, radiosensitizers, and genetic material.8
Unlike previous … therapeutics, such as plasmids, antisense oligonucleotides, and small interfering RNA (siRNA … carriers for dual drugs delivery. Drug Deliv. 2016; … . Artif Cells Nanomed Biotechnol. 2020;48(1): …
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Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway
04 Aug 2025 11:04 GMT
… ), all purchased from Shanghai Zhuocai Biotechnology Co., Ltd. China. Subsequently, horseradish … , AC026), all purchased from Abclonal Biotechnology Co., Ltd. China. The membranes … -α expression. Compared to the siRNA-Tollip M1 drug serum 10% group, the …
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Application of Nanotechnology in TACE Treatment of Liver Cancer
04 Aug 2025 11:04 GMT
… of HCC/TPE@siRNA-SP94 by testing its … -medicine. Artif Cells Nanomed Biotechnol. 2018;46(sup1):1210 … overcoming biological barriers to drug delivery. Nature Biotechnol. 2015;33(9 … emerging paradigm for targeted drug delivery system. Biotechnol Adv. 2013;31 …
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Lp(a): Aiming at a Moving Target, Waiting for Ammunition
04 Aug 2025 09:33 GMT
… . No Lp(a)-lowering drug has been approved, and while … is that it is a genetic biomarker. As such, levels … trials: Zeriasiran, a subcutaneous siRNA agent that has shown up … , Ionis, Novartis, and NewAmsterdam Pharma. Shah reported having received research …
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Regeneron Pharmaceuticals, Inc. (NASDAQ:REGN) Q2 2025 Earnings Call Transcript
02 Aug 2025 12:35 GMT
… , patients taking a 4-drug combination standard of care containing … with our Regeneron Genetic Medicines pipeline. Our C5 siRNA and antibody … get familiar with many different drugs in this allergy spectrum … to be a much preferred drug than EYLEA or PAVBLU.
…