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<![CDATA[Pirtobrutinib Offers Potential Second-Line Treatment in CLL]]>
26 Sep 2025 19:14 GMT
… obinutuzumab [Gazyva] or rituximab [Rituxan] as their next line [ … in the College of Medicine at The Ohio State … indicated by the FDA for the treatment of adult patients … ;www.fda.gov/drugs/;resources-information-approved-drugs/fda-grants-accelerated …
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<![CDATA[Breaking Down The SUNMO Trial on M-Pola in ASCT-Ineligible R/R LBCL]]>
25 Sep 2025 03:51 GMT
… ; M-Pola) compared with rituximab (Rituxan) plus gemcitabine and oxaliplatin (R … associate professor of medicine at The Warren Alpert Medical School of Brown … ] first-line treatment. This trial, [unlike] some other recently reported trials, enrolled high …
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<![CDATA[Determining Fitness Is Key in Mantle Cell Lymphoma Treatment Selection]]>
23 Sep 2025 21:53 GMT
… of Medicine (Hematology) at Yale University.
Transcript:
The current treatment … changed among most lymphoma doctors. That is based off … we typically go for rituximab [Rituxan] and bendamustine [Treanda]- … , although we have clinical trials ongoing here, so we …
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<![CDATA[Indirect Comparison Favors Zanubrutinib vs Venetoclax Combo in CLL/SLL]]>
27 Sep 2025 01:42 GMT
… adjusting for baseline characteristics between trials, investigators reported significantly prolonged PFS … of bendamustine (Treanda) plus rituximab (Rituxan) in arm B; those with … -label, phase 3 CLL14 trial assessed treatment with 12 cycles of chlorambucil …
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<![CDATA[Mosunetuzumab Combo Yields Differentiated Safety Profile Vs SOC in LBCL]]>
27 Sep 2025 01:42 GMT
… M-Pola) vs rituximab (Rituxan) plus gemcitabine and oxaliplatin (R … Regarding safety, the trial showed that treatment-related adverse events ( … least 5% between the treatment arms that were more … professor of medicine at The Warren Alpert Medical School of …
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ATyr shares plunge on trial miss in inflammatory lung disease
15 Sep 2025 17:47 GMT
… Brief:
An experimental drug from biotechnology company aTyr Pharma missed … nearly a year of treatment.
The drug, called efzofitimod, is … use of other drugs like methotrexate or Rituxan.
At the … highest dose tested in the clinical trial, …
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Pirtobrutinib Improves Survival in Treatment-Naive CLL/SLL
08 Sep 2025 19:57 GMT
… 3 BRUIN CLL-313 trial (NCT05023980) showed that … and rituximab (Rituxan; BR) in patients with treatment-naïve chronic … study [NCT05254743], at upcoming medical meetings and preparing global … the results of ongoing confirmatory trials.
REFERENCES:
1. Lilly…
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Pirtobrutinib Improves PFS in Treatment-Naïve CLL/SLL Without 17p Deletions
08 Sep 2025 18:25 GMT
… trial (NCT05023980) that evaluated pirtobrutinib monotherapy vs bendamustine (Treanda) plus rituximab (Rituxan … with previously reported trials across various treatment settings.
" … [NCT05254743], at upcoming medical meetings and preparing global …
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Pirtobrutinib Monotherapy Meets Primary PFS End Point in Treatment-Naive CLL/SLL
08 Sep 2025 20:55 GMT
… rituximab (Rituxan; BR) in patients with treatment-naive chronic … from previously reported trials across various treatment settings.
Together, … trial, according to Eli Lilly and Company, the drug’ … study, at upcoming medical meetings and preparing global …
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Tafasitamab: A New Horizon for Follicular Lymphoma Treatment
05 Sep 2025 17:15 GMT
… lymphoma.
When analyzing various treatment regimens for follicular lymphoma, … lenalidomide (Revlimid) and rituximab (Rituxan) combination. This is particularly … combination. Of the 3 drugs, lenalidomide is the … rituximab. In the clinical trial, the addition of …