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Starfish compound overcomes drug resistance in prostate cancer models
06 Aug 2025 05:56 GMT
… offering new hope for tackling treatment-resistant disease.
Study: Anticancer … , yet most tumors become drug-resistant, castration-resistant, or … B/mechanistic target of rapamycin (PI3K/AKT/ … line 1 (RWPE-1), Medical Research Council cell strain 9 …
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Advances and Challenges in Nano-Delivery Systems for Glioblastoma Treatment: A Comprehensive Review
04 Aug 2025 11:04 GMT
… US Food and Drug Administration (FDA)-approved for various … ROS amplification.71 Dendrimer-rapamycin conjugates achieved TAM … UTMD. Artif Cells Nanomed Biotechnol. 2020;48(1): … photothermal-chemotherapy treatment of glioblastoma. J Pharmaceut Sci. 2025 …
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Palvella Therapeutics to Participate in the Canaccord Genuity 45th Annual Growth Conference
05 Aug 2025 11:30 GMT
… are no Food and Drug Administration (FDA)-approved therapies, … led by rare disease drug development veterans, Palvella … which there are no FDA-approved therapies. Palvella … rapamycin), is currently being evaluated in the Phase 3 SELVA clinical trial …
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Cassava Sciences Reports Positive Preclinical Study Evaluating Simufilam for TSC-Related Epilepsy
04 Aug 2025 11:30 GMT
… the mechanistic target of rapamycin (mTOR) pathway … biotechnology company focused on developing novel, investigational treatments, … cortical malformations.. Science Translational Medicine. (2020) 12(531 … All of our pharmaceutical assets under development …
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Synthetic Cell Can “Follow Chemical Directions and Change Shape” Mimicking Life’s Most Vital Functions in Breakthrough Study
06 Aug 2025 06:40 GMT
… . When exposed to the chemical rapamycin, these proteins triggered a process … synthetic cells capable of targeted drug delivery, environmental sensing, and other … to safer and more effective medical treatments, or will they introduce new …
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Tabernanthalog Spurs Neuroplasticity Without Immediate Gene Activation
04 Aug 2025 14:24 GMT
… mammalian target of rapamycin (mTOR) and … cellular mechanisms to antidepressant-like effects in … disorders demands rigorous trials to assess safety … researchnonhallucinogenic psychoplastogenspsychiatric disorder treatmentsresearch in Nature …
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This protein molecule in your body could be the answer to increasing your lifespan
03 Aug 2025 14:09 GMT
… are being tested in human trials.
But what is IL-11 … when mice are treated with rapamycin. However, rapamycin has also been known … effects of this treatment on human longevity through clinical trial is a …
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Brain aging linked to sluggish production of key proteins
02 Aug 2025 20:07 GMT
… experimental timelines feasible for doctoral students as well as grant … researchers are already testing drugs like rapamycin, which targets the cell … promise in Alzheimer’s trials focused on safety and … , low-cost testing of drug responses.
If those tools …
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Long Non-Coding RNA lncTAF15:1-1 Promotes CCL5 Secretion and Cell Migration of Monocyte-Derived Dendritic Cells via PI3K/AKT/mTOR Pathway in Systemic Lupus Erythematosus
02 Aug 2025 15:23 GMT
… seq was performed by OE Biotech Co., Ltd. (Shanghai … strategy for SLE treatment, adding translational relevance … medicine in gastric cancer: early diagnosis, treatment, and drug resistance … nephritis and downregulated by rapamycin. Nephrol Dial Transplant. …
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Focus on Cell Apoptosis, Pyroptosis and Ferroptosis to Explore Strategic Breakthrough for GDM
02 Aug 2025 05:45 GMT
… treatment and lifestyle modification,16 with the latter including medical … GDM or large clinical trials will be used … : The autophagy agonist rapamycin significantly blocked the down … Metformin, a widely used pharmaceutical agent that enhances insulin …