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Pharmacokinetics and Safety of HRS-1780 in Renal Impaired Subjects: A Multicenter, Non-Randomized, Open-Label Study
08 May 2025 12:51 GMT
… Administration Guidance for Industry Pharmacokinetics in Patients with Impaired … to assess safety, tolerability, pharmacokinetics, pharmacodynamics, and concentration-QTc … Halabi A, Lentini S. Pharmacokinetics of the novel nonsteroidal mineralocorticoid …
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A Natural Compound Methylnissolin: Physicochemical Properties, Pharmacological Activities, Pharmacokinetics and Resource Development
08 May 2025 12:51 GMT
… physicochemical properties, biological activity, pharmacokinetics, and influencing factors, providing … D, Ma BL. Preclinical pharmacokinetics-related pharmacological effects of orally … free web tool to evaluate pharmacokinetics, drug-likeness and medicinal …
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Successful Extension of Nucleic Acid Aptamer Pharmacokinetics in Joint Research by Ajinomoto Co., Inc. and RIBOMIC Inc.
07 May 2025 02:45 GMT
… of technology for controlling the pharmacokinetics of nucleic acid aptamers using … -extension-of-nucleic-acid-aptamer-pharmacokinetics-in-joint-research-by-ajinomoto …
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Minimally Invasive Stroke Model for Awake Mice
10 May 2025 17:43 GMT
… testing revealed differential efficacy and pharmacokinetics compared to traditional ischemia models …
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IL7-IL7R Interaction Mediates Fibroblast-Driven Macrophage-to-Osteoclast Differentiation in Periodontitis
10 May 2025 13:11 GMT
… . Model-based characterization of the pharmacokinetics, target engagement biomarkers, and immunomodulatory …
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Corvus Pharmaceuticals, Inc. (NASDAQ:CRVS) Q1 2025 Earnings Call Transcript
10 May 2025 12:27 GMT
… our studies of occupancy and pharmacokinetics, we determined that Cohort 4 …
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Novel STAT3 Inhibitor TT1-101 Is Safe and Shows Antitumor Activity in R/R HCC and Other Solid Tumors
09 May 2025 19:27 GMT
… lower than at DL3, and pharmacokinetics were linear from DL1 through … that TTI-101 exhibited linear pharmacokinetics from DL1 to DL3; however … manageable safety profile and consistent pharmacokinetics supportive of continued clinical development …
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Durvalumab Plus BCG Improves Survival in Early Bladder Cancer
09 May 2025 19:14 GMT
… specific PRO CTCAE symptoms, and pharmacokinetics are secondary end points of …
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FDA Fast-Tracks Novel ADC in Cervical Cancer
09 May 2025 19:14 GMT
… . The secondary end points include pharmacokinetics, objective response rate, duration of …
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Capivasertib, Fulvestrant Show Promise in Advanced Breast Cancer
09 May 2025 16:04 GMT
… polymorphisms, tumor mutational landscapes, and pharmacokinetics can influence therapeutic efficacy and …