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US FDA clears Instil Bio's IND application for AXN─2510, a PD─L1xVEGF bispecific antibody, for a phase 1 trial in relapsed/refractory solid tumours
04 Jul 2025 06:05 GMT
… to evaluate the safety, efficacy, pharmacokinetics and pharmacodynamics of ‘2510 in …
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Jacobio Pharma submits phase I/II IND application for its BET inhibitor, JAB-8263 to treat autoimmune diseases to CDE in China
04 Jul 2025 07:43 GMT
… Jacobio Pharma. Its safety and pharmacokinetics have been evaluated in early …
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Brii Biosciences Announces Licensing Agreement with Joincare Group for Rights to BRII-693 in Greater China
04 Jul 2025 02:00 GMT
… of therapeutic potential, pharmacodynamics, and pharmacokinetics, suggesting BRII-693's …
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Infection Leading to Breast Abscess Formation in Pregnancy: A Case Report
04 Jul 2025 00:34 GMT
… clindamycin, while evaluating pregnancy-specific pharmacokinetics and fetal safety profiles. Clinical …
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Comparison of Subconjunctival Triamcinolone with Topical Prednisolone for Routine Anti-Inflammatory Prophylaxis in Manual Small Incision Cataract Surgery: A Single-Center, Randomized Controlled Trial Pilot Protocol
04 Jul 2025 00:34 GMT
… .08.039
13. Shell JW. Pharmacokinetics of topically applied ophthalmic drugs …
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Insilico Medicine Unveils AI-Powered Innovative Design Strategy for Highly Selective FGFR2/3 Inhibitors
03 Jul 2025 20:25 GMT
… optimized binding thermodynamics and favorable pharmacokinetics. The computationally designed molecule ISM7594 … predictive modeling of pharmacodynamics and pharmacokinetics. This confluence of biology, chemistry …
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Q2 2025: A recap of the top headlines and interviews
03 Jul 2025 18:40 GMT
… to 17 years confirmed consistent pharmacokinetics with adult data and showed …
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Cancer drug identified that also works to slow Parkinson's disease, according to scientists
03 Jul 2025 18:27 GMT
… many safety hurdles.
Opdualag’sTM pharmacokinetics, dosing, and adverse‑event profile …
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Significant Predictors of Azithromycin in Population Pharmacokinetic Analysis: A Systematic Review
03 Jul 2025 15:27 GMT
… identify azithromycin (AZM) population pharmacokinetics studies.
Notes: PRISMA figure … . Significant predictors for olanzapine pharmacokinetics: a systematic review of … in ureaplasma-infected preterm infants: pharmacokinetics, safety, microbial response, and …
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Artificial Intelligence-Driven Innovations in Oncology Drug Discovery: Transforming Traditional Pipelines and Enhancing Drug Design
03 Jul 2025 15:28 GMT
… However, several drawbacks (eg, poor pharmacokinetics, low potency, and remarkable toxicity … because of its established poor pharmacokinetics, low potency, and remarkable nephrotoxicity …