Nearly 30 years ago, two hallmark papers studying acute peritoneal infections reported evidence for protective functions of mast cells in anti-bacterial defense1,2. These experiments were performed in mice carrying inactivating mutations in the gene …

On 12 June 2025, Vascarta Inc. announced its receipt of the Orphan Drug Designation from the US Food and Drug Administration (FDA) for its lead drug candidate, VAS-101 (Vasceptor), to treat sickle cell disease (SCD). This designation will provide VAS-101 …

The immune system is made up of a network of tissues and circulating cells whose primary function is to prevent and limit pathogenic infections (Danilova, 2006; Pradeu et al., 2024; Schmid-Hempel, 2021). Although immunity has been studied in many animal …

… dock versus another. That explains pharmacodynamic efficacy and adverse effects, respectively … is zero vs first order kinetics? Tertiary vs secondary amine tricyclics … Interaction Table. Division of Clinical Pharmacology, Indiana University School of Medicine …

… . Eric Morand showcased clinical, cellular kinetics, pharmacodynamics, and biomarker outcomes up to … ., et al. (2025) Clinical, Cellular Kinetics, Pharmacodynamics and Biomarker Data Up to …

… ; Abbott Labs, 700; Covidien, 595; Kinetic Concepts, 427; St. Jude Medical … with almost 480 layoffs. As Pharmalot reports, the company notified the …

… revolutionary Boomer protesters for dinner, medication, and the nightly MSNBC shows … out of judicial warfare to kinetic action in the streets.  Terrible …

… to work. A truly effective medication not only needs to kill … Metronidazole: Design, Evaluation, and Release Kinetics” by Olga Adamczyk, Aleksandra Deptuch …

… amp;D cycle, elucidating drug pharmacokinetic preclinically, and reducing the … , Vasic VM. Acetylcholinesterase inhibitors: pharmacology and toxicology. Curr Neuropharmacol. 2013 … biointerface analysis and in vitro kinetic analysis of amine compounds …

… be paid to understanding the kinetics of EV distribution in the … Nanoparticles to Mice Brain. Front Pharmacol. 2022;13:819516. doi:10 …