-
<![CDATA[Multidisciplinary Team Discusses Practical Treatment Options in NSCLC ]]>
26 Sep 2025 19:19 GMT
… Chair in Medical Oncology.
Efficacy Observed Across Key Trials
Kim … followed by pembrolizumab/pemetrexed maintenance vs the placebo … 4-drug regimen.
The phase 3 CheckMate 9LA trial [NCT03215706 … just let the [doctor] be aware.
Radiation Treatment
Kim / …
-
<![CDATA[Sunvozertinib Approval Fills Treatment Gap in Pretreated EGFR Exon 20–Mutant NSCLC]]>
26 Sep 2025 19:14 GMT
… pemetrexed, and amivantamab-vmjw [Rybrevant] as a standard first-line treatment … (UCSD) and a medical oncologist at UCSD Moores … from the WU-KONG1B trial, and emphasized how … ;www.fda.gov/drugs/;resources-information-approved- drugs/fda-grants- …
-
<![CDATA[Beamion LUNG-1: Examining the Efficacy and Safety of Zongertinib in 2L Treatment of mNSCLC With HER2 Mutations]]>
25 Sep 2025 02:50 GMT
… Zongertinib represents the first FDA-approved HER2-specific tyrosine … New England Journal of Medicine with John Heymach as … had received prior carboplatin, pemetrexed, with or without pembrolizumab, … care, with ongoing frontline trials (Beamion LUNG-2) comparing …
-
<![CDATA[Evaluating the Top EGFR+ NSCLC Treatment Combinations]]>
20 Sep 2025 15:20 GMT
… the phase 3 MARIPOSA trial (NCT04487080)—amivantamab-vmjw ( … Center of Johns Hopkins Medicine in Baltimore, Maryland. … plus lazertinib, the treatment recommendations are tailored to … , continuing that maintenance pemetrexed sometimes has some increased …
-
<![CDATA[FDA Approves Subcutaneous Pembrolizumab for Solid Tumors ]]>
20 Sep 2025 01:09 GMT
… intravenous pembrolizumab, with pemetrexed maintenance therapy administered … were considered serious. Treatment discontinuation due to … .fda.gov/drugs/;resources-information-approved-drugs/fda-approves … in pivotal 3475A-D77 trial. News release. Merck. …
-
AstraZeneca’s Saphnelo SC shows reduction in disease activity in SLE trial
18 Sep 2025 22:57 GMT
… remission as an achievable treatment goal for more … trial for non-small cell lung cancer (NSCLC) when used alongside pemetrexed … deserve! The Clinical Trials Arena Excellence Awards celebrate … top leaders driving clinical trials industry advancements. Don’ …
-
<![CDATA[Frontline Treatment Options for mNSCLC With HER2 Mutations]]>
17 Sep 2025 16:40 GMT
… FDA-approved matched targeted therapy available and no standard first-line treatment … the KEYNOTE-189 regimen (carboplatin, pemetrexed, and pembrolizumab) for standard … chemotherapy alone with carboplatin and pemetrexed may be considered. However, …
-
AstraZeneca PLC (AZN) Receives Tagrisso Boost in Lung Cancer Trials
15 Sep 2025 13:10 GMT
… trial results involving Tagrisso in combination with pemetrexed … Trials Pixabay/Public Domain The trial … medicines. Tagrisso is AstraZeneca’s top-selling cancer drug. While the drug … and marketing innovative medicines for the treatment of various diseases …
-
FLAURA-2 and HARMONi Trial Readouts Reinforce Importance of ‘Divide and Conquer’ Approach to Lung Cancer Care at WCLC 2025
11 Sep 2025 18:36 GMT
… MD, thoracic medical oncologist, early drug development specialist, Memorial … FLAURA2 trial (NCT04035486), which suggest a role for treatment … trial was designed, which was to continue the pemetrexed … being developed by other pharmaceutical companies as well. …
-
Baylor and Duke Launch Mesothelioma Trial Testing Chemoimmunotherapy
11 Sep 2025 01:40 GMT
… and durvalumab (Imjudo®). These medicines work by teaching the … immunotherapy drugs plus the two chemotherapy drugs cisplatin and pemetrexed. … trial, Donchig not only gained access to advanced treatments … matched with other active trials in your area …