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Adjuvant CDK4/6 Inhibition Gains Further Ground in HR+/HER2– Early Breast Cancer With Ribociclib Approval
02 May 2025 22:56 GMT
… the FDA approval of the PARP inhibitor olaparib (Lynparza) has improved …
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Jenny's story
02 May 2025 11:38 GMT
… of maintenance treatment (known as PARP inhibitors which can help reduce …
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(Update) Best NMN Supplements In 2025, According To Experts
02 May 2025 07:03 GMT
… DNA repair. NAD works with PARP, an enzyme that is crucial …
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Sylvester Comprehensive Cancer Center Unveils Key Insights for ASCO 2025
01 May 2025 15:01 GMT
… ’Amato, the study compares the PARP inhibitor olaparib plus temozolomide against …
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Improving Outcomes with Combination Therapies for PSMA Radioligand Treatment "Presentation" - Michael Hofman
30 Apr 2025 22:52 GMT
… damage? And the principle behind PARP inhibitors is that we… , and potentially by adding a PARP inhibitor, we can convert some … , and we think that continuous PARP inhibition may not be warranted … little trick as with the PARP inhibitors. We do lutetium day …
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GSK’s Zejula reduces risk of progression and death in mesothelioma study
30 Apr 2025 17:46 GMT
… oral poly-ADP ribose polymerase (PARP) inhibitor that was approved on … , or primary peritoneal cancer.
Other PARP inhibitors being investigated in patients …
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Mabwell Releases 6 Study Results Of Innovative Drugs And Platforms At The 2025 AACR Annual Meeting
30 Apr 2025 15:55 GMT
… antibody-drug conjugate, 7MW3711, and PARP inhibitors synergistically potentiate the antitumor …
Published Abstract Number: 830
Both PARP inhibitors and B7-H3-targeting … its self-developed 7MW3711 with PARP inhibitors to explore the synergistic …
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6-((1,4-naphthoquinone-2-yl)methyl)thio-glucose conjugates, a novel targeted approach for advanced prostate cancer.
30 Apr 2025 14:01 GMT
… -strand breaks. Combinational therapy with PARP-inhibitor olaparib resulted in synergistic … of caspases-3 and -9, PARP cleavage, and apoptotic cell death … potential combination partner, especially with PARP inhibitors.
Molecular cancer therapeutics. 2025 …
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Rakovina Therapeutics Inc. Announces 2024 Financial Results and Provides Corporate Update
30 Apr 2025 12:30 GMT
… product profile for a PARP-1 selective lead candidate … drug candidates: AI-generated PARP-inhibitor compounds for in vitro … generative Artificial Intelligence (AI) PARP-inhibitor program at the … -molecule bifunctional inhibitor of PARP and HDAC enzymes at …
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Advances in Targeted Therapy for Metastatic Prostate Cancer.
30 Apr 2025 14:01 GMT
… of poly-ADP-ribose-polymerase (PARP) inhibitors in metastatic prostate cancer … (CRPC), we favor combining a PARP inhibitor (PARPi) with an AR …