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Metal-Organic Frameworks as Advanced Gene Delivery Vectors: Mechanisms, Functionalization, and Biomedical Applications
24 Oct 2025 14:10 GMT
… by transmitting functional genes or regulating gene expression. This technology … cell apoptosis by restoring p53 protein function in vivo. Further … .98
Gene Transfer Therapy
Gene therapy methods include gene transfer … A, Masoomi MY. P53 gene therapy with ZIF-8 …
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Why Genetically Modified Crops Need A Trait-based Naming Typology
20 Oct 2025 17:36 GMT
… DNA lesions in p53 or BRCA genes. Therefore, the … it. It has multiple proteins that can act against … organism treat activities involving genetically engineered organisms as … Committee on Genetic Manipulation (RCGM), the Genetic Engineering Appraisal …
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Book Review: The Right to Oblivion: Privacy and the Good Life
23 Oct 2025 12:26 GMT
… to the production of information” (p. 53). Pressly’s focus on human … researchers, from those with a general interest in privacy studies to …
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Rhubarb: Traditional Uses, Phytochemistry, Multiomics-Based Novel Pharmacological and Toxicological Mechanisms
23 Oct 2025 00:52 GMT
… -like receptor thermal protein domain-associated protein 3 (NLRP3) … treated with emodin, gene expression and protein levels of UGT2B7 … and protein levels, indicating that NF-κB and p53 signaling … -like receptor thermal protein domain-associated protein 3; Nrf2, …
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<![CDATA[Convergent and Divergent Signaling Pathways in Cancer: A Dual-Axis Model for Adaptive Precision Oncology]]>
25 Oct 2025 18:16 GMT
… strategies, including next-generation sequencing and liquid biopsies … frequently dysregulated through genetic or epigenetic mechanisms … as a gene-level input, whereas p53 refers to … data and known protein-protein interactions were constructed …
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Scientists Just Found a Surprising Link Between Gray Hair and Cancer
25 Oct 2025 16:05 GMT
… long-term lineage tracing and gene expression profiling in mice, the … by the activation of the p53-p21 signaling pathway.
When McSCs …
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Honeysuckle-Derived Exosome-Like Nanovesicles Protect Against Acute Liver Failure by Modulating Gut Microbiota
25 Oct 2025 13:47 GMT
… finally collected. The BCA Protein Concentration Kit (P0012, Beyotime … indicated that P62 protein expression was significantly up … increased the expression of P53 protein in liver tissues ( … Biological functions of autophagy genes: a disease perspective. Cell …
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The Relationship Between IL-6 and IL-10 Expression Levels and the Prognosis in B-Cell Non-Hodgkin Lymphoma Patients Treated with R-CHOP
25 Oct 2025 13:48 GMT
… During blood coagulation, certain proteins, such as fibrinogen, … , C-reactive protein, and other related proteins, thereby indirectly … cytokines, and Bcl2 and p53 molecules. Cancer Biother Radio … in enhanced acute-phase protein genes by neonatal macrophages …
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Grey hair maybe linked to body's cancer defense mechanism, new study suggests
25 Oct 2025 11:50 GMT
… base of hair follies and generate mature melanocytes and go through … to the activation of the p53–p21 pathway," a tumour …
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PMV Pharmaceuticals Announces Updated Rezatapopt Monotherapy Interim Data From Ongoing PYNNACLE Phase 2 Trial Across Multiple Solid Tumors With a TP53 Y220C Mutation
24 Oct 2025 15:39 GMT
… , tumor-agnostic therapies targeting p53, today announced updated data … cancer, while continuing to generate additional data to support … the pocket in the p53 Y220C mutant protein, restoring the wild … field of p53 biology when he discovered the p53 protein in …