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Treatment Challenges, Options for People With MS and Comorbid Inflammatory Diseases
09 Sep 2025 00:46 GMT
… searched PubMed for clinical trials, case studies, and … ocrelizumab, rituximab, and ofatumumab were identified as effective … could mean fewer medications and potentially less treatment burden, though … with limited randomized controlled trial data. Most studies …
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Directed-Complement Activation as a Novel Immunotherapeutic Approach for HER2-Breast Cancer
05 Sep 2025 08:19 GMT
… mAb approved for breast cancer treatment, inhibits the human epidermal … Breast cancer drugs: FDA approval, development time, efficacy, clinical benefits, innovation, trials, … complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia …
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April - June 2021 | Potential Signals of Serious Risks/New Safety Information Identified by the FDA Adverse Event Reporting System (FAERS)
29 Aug 2025 20:22 GMT
… based on available information.
Arzerra (ofatumumab)
Gazyva (obinutuzumab)
Riabni (rituximab … zirconium cyclosilicate)
Gastrointestinal disorders
FDA determined that no action is …
Sarclisa labeling
Sprycel (dasatinib)
Drug-induced liver injury
The “Warnings …
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Emerging MS Treatments Offer New Hope for Progressive Disease
09 Aug 2025 00:13 GMT
… MS (nrSPMS).1 The drug acts on microglia, macrophages, … new therapies advancing through trials—particularly BTKis like tolebrutinib … agents like ocrelizumab and ofatumumab—with transforming care in … on novel multiple sclerosis treatments: from dismal defeat to …
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Restricted Drug Coverage Tied to Higher Risk for MS Relapse
08 Aug 2025 12:16 GMT
… chair in the Department of Pharmaceutical and Health Economics at … getting their prescribed medication, such as drugs for relapsing-remitting … ; MA-DP, 43.3%), ofatumumab (PDP, 99.6%; MA- … out-of-pocket drug expenses.
“Innovative new treatments have made it …
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Advances in MS Therapies Reshape the Treatment Landscape
08 Aug 2025 06:38 GMT
… rituximab, ocrelizumab, and ofatumumab, have proven highly effective … the success of these treatments in preventing relapses, … the pharmaceutical industry, or by traditional billion-dollar trials. … , to interrogate large medical databases, among others, …
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Generic Ibrutinib Tablets Earn Tentative FDA Approval in Blood Cancers
24 Jul 2025 19:18 GMT
… of 484 abbreviated new drug applications since the beginning … of treatment were eligible for enrollment on the trial.3 … a phase 2 trial (NCT02604511) from Dana-Farber Cancer Institute, in … ibrutinib (PCI-32765) versus ofatumumab in patients with relapsed or …
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Primary Progressive Multiple Sclerosis (PPMS) Treatment Market Analysis 2025 – Long-Term Investment & Planning Insights
24 Jul 2025 11:55 GMT
… Phase III clinical trials reached 33 … Therapeutics Inc., MediciNova Inc., MedDay Pharmaceuticals SAS, AB … multiple sclerosis treatment. These drugs target specific … Antibodies: Ocrelizumab, Rituximab, Ofatumumab, Ublituximab
2 Immunosuppressants: …
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Generic Ibrutinib Tablet Given Tentative FDA Approval in CLL/SLL, WM
25 Jul 2025 19:04 GMT
… 5 randomized, controlled trials, including the RESTONATE trial (NCT01578707).3 RESONATE … investigators randomized patients to treatment with ibrutinib or ofatumumab (Kesimpta), including … 47;/www.accessdata.fda.gov/drugsatfda_docs/appletter…
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Obinutuzumab is Effective as an Initial Treatment for PLA2R-Associated Primary Membranous Nephropathy: A Retrospective, Single-Center Trial
11 Jul 2025 13:29 GMT
… ofatumumab.8–10 Notably, recent randomized controlled trials … of Inner Mongolia Medical University (Hohhot) … receipt of the treatment drug. This retrospective … treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial …