… metabolic phenotypes. Among these, obesity-prone and obesity-resistant phenotypes are particularly … associated with clinical characteristics. Obese T2DM patients exhibited variations in … Bluher M, Kovacs P. The genetics of fat distribution. Diabetologia. 2014 …

… as treating muscle loss in obese patients, both as standalone … designed to advance human obesity care by preserving muscle mass … vector operably linked with gene encoding myostatin and activin … probiotic approach to address obesity’s pressing issue of …

… validate these preliminary results. Background Obesity, a condition characterized by unwanted … that obesity arises from a complex and multifaceted interplay among genetics, lifestyle … (n = 45 metabolites). 16S rRNA gene metagenomics confirmed these findings by …

… treat the root causes of obesity and type 2 diabetes ( … treatment of metabolic diseases, including obesity and T2D. Despite advances in … the last 50 years, obesity and T2D continue to be … , locally delivered gene therapies for the treatment of obesity and T2D. …

… health plans expect affordability of gene therapy for their health … plans expect affordability of gene therapy for their health … replacing, or turning off genes,” come with high prices such … more Americans flock to anti-obesity GLP-1 medicines, prescriptions …

… that people who were not obese at baseline and consumed artificial … less adipose tissue…such as genetics and other environmental factors that … colleagues found that participants with obesity showed the greatest appetite-stimulating …

… against reductionist interpretations of obesity. While genes and hormones play pivotal … of contemporary living. By bridging genetics, endocrinology, evolutionary theory, and … 025-01791-9 Keywords: Obesity, Thrifty Gene Hypothesis, General Adaptation Syndrome …

… maternal obesity on fetal overgrowth indicators. Infants born to obese mothers … transfer. Furthermore, discordance in gene expression regulated by epigenetic … , this research bridges population genetics with obstetric epidemiology, highlighting the …

… by metabolic disorders like obesity and type II diabetes … pro-apoptotic genes while silencing anti-apoptotic genes via hypermethylation, … in the modulation of gene expression and their stability … nuanced understanding of tumor genetics and patient profiles.77 …

… comprehensive information on druggable genes. eQTL Datasets Our gene expression data were … . Obstructive sleep apnea syndrome and obesity indicators, circulating blood lipid levels … studies using summary statistics. PLoS Genetics. 2014;10(5):e1004383. doi …