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Metastatic Brain Tumor Collaborative Announces First-Ever Collaborative Grant Opportunity Focused on CNS Metastasis
15 Oct 2025 17:21 GMT
… larger-scale funding.
"Metastatic brain tumors are devastating, and yet, … quot;
About the Metastatic Brain Tumor Collaborative
The Metastatic Brain Tumor Collaborative is a … the lives of patients with brain metastases through research, education, …
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Cullinan Therapeutics Cancer Drug Shows Efficacy In Brain Metastases Among Lung Cancer Patients With Certain Mutations
13 Oct 2025 17:38 GMT
… zipalertinib.
An incidence of baseline brain metastases in EGFR ex20ins NSCLC patients … Assessment in Neuro-Oncology for Brain Metastases (RANO-BM) criteria evaluable population …
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<![CDATA[Osimertinib Plus Local Consolidative Therapy Significantly Extends PFS in EGFR-Mutant NSCLC]]>
18 Oct 2025 01:17 GMT
… induction osimertinib, and presence of brain metastases (yes vs no).
LCT modalities … both arms did not have brain metastases (63.5% vs 62.5% …
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<![CDATA[Sevabertinib Effective in Pretreated and First-Line HER2-Mutant NSCLC]]>
17 Oct 2025 22:21 GMT
… treatments, presence of baseline brain metastases, and receipt of prior … in patients with and without brain metastases. In cohort D, …
In patients who had brain metastases at baseline in cohorts … In those with no brain metastases at baseline in cohorts D …
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<![CDATA[Lenvima Combo Fails to Extend Survival in Esophageal Cancer]]>
17 Oct 2025 22:21 GMT
… of patients did not have brain metastases and had stage 4B disease …
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<![CDATA[Sevabertinib Monotherapy Shows Robust Response in HER2-Mutant NSCLC]]>
17 Oct 2025 20:44 GMT
… treatments, presence of baseline brain metastases, and receipt of prior … than 1-15).
Further, brain metastases were present in 22% of … in patients with and without brain metastases. In cohort D, … In those with no brain metastases at baseline in cohorts D …
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<![CDATA[Zongertinib Shows 77% ORR in First-Line HER2-Mutant NSCLC]]>
17 Oct 2025 20:45 GMT
… who had stable/asymptomatic brain metastases were eligible for treatment.
The … never used tobacco, 30% had brain metastases, and 66% had A775_G776insYVMA …
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<![CDATA[LEAP-014: Lenvatinib Triplet Fails to Improve OS in Metastatic ESCC]]>
17 Oct 2025 20:44 GMT
… of patients did not have brain metastases and had stage IVB disease …
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<![CDATA[First-Line Zongertinib Yields Strong Responses in Patients With Advanced HER2-Mutant NSCLC]]>
17 Oct 2025 17:12 GMT
… showed activity in patients with brain metastases, a common occurrence in this … . Patients with stable/asymptomatic brain metastases were eligible.2
According to …
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Indiana biotechnology startup Quornix wins top Cade prize for innovation
17 Oct 2025 16:41 GMT
… , pediatric high-grade gliomas and brain metastases.
Wildcard: Floe of New Haven …
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