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New machine learning model brings transparency to risk prediction in medulloblastoma
23 Jun 2025 19:43 GMT
… , particularly for high-risk medulloblastoma subgroups. Future research may … accuracy and treatment strategies for medulloblastoma patients."
In conclusion, … of immune microenvironment associated with medulloblastoma metastasis based on explainable …
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MDM2 inhibition is an approach for medulloblastoma management
11 Jun 2025 20:37 GMT
Cancer
Loss-of-function variants in the ELP1 gene are the most prevalent predisposing genetic factors in childhood medulloblastoma, accounting for about 30% of sonic hedgehog medulloblastoma (SHH-3 subtype).
BioWorld Science Cancer
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Immunotherapeutic Targets for Recurrent Medulloblastoma Receives $85K Grant from Brain Cancer Canada
28 May 2025 13:00 GMT
… an Immunotherapeutic Target for Recurrent Medulloblastoma," aims to develop a … four subgroups, with Group 3 medulloblastoma (G3MB) representing the most aggressive … and cell surface ONLY in medulloblastoma cells presents an unexpected opportunity …
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Protein Target Increases Vulnerability of Childhood Medulloblastomas to Cell Death
21 May 2025 08:45 GMT
… brain cancers.
Particularly, Group-3 medulloblastomas are aggressive and incurable, contributing … DLAT also made Group-3 medulloblastomas more sensitive to copper-dependent … dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis. Cancer Cell. 2025 …
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New Protein Target for Childhood Medulloblastomas
20 May 2025 12:52 GMT
… brain cancers.
Particularly, Group-3 medulloblastomas are aggressive and incurable, contributing … new target for Group-3 medulloblastomas.
The results help identify new … DLAT also made Group-3 medulloblastomas more sensitive to copper-dependent …
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Researchers Discover New Protein Target for Childhood Medulloblastomas
19 May 2025 20:03 GMT
… brain cancers.
Particularly, Group-3 medulloblastomas are aggressive and incurable, contributing … DLAT also made Group-3 medulloblastomas more sensitive to copper-dependent … Dehydrogenase 1 Primes Group-3 Medulloblastomas For Cuproptosis,” Cancer Cell. DOI …
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Scientists Identify Novel Protein Target in Childhood Medulloblastoma Research
19 May 2025 17:21 GMT
… subtypes, Group-3 medulloblastomas represent a particularly aggressive … cell death pathwayGroup-3 medulloblastoma treatment optionsinnovative therapies for … in cancertargeted interventions for medulloblastomatranscriptomic analysis of brain tumorsUniversity …
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Study Reveals Targetable Mechanism Behind High-Risk Predisposition Gene in Pediatric Medulloblastoma
16 May 2025 00:16 GMT
… a type of pediatric medulloblastoma. Children who inherit a … risk of developing SHH-medulloblastoma, a subtype of a … predisposing children to SHH-medulloblastoma seven years ago, but … a targeted therapy for SHH-medulloblastoma,” Northcott said.
MDM2 …
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Oncogenes Fuel Medulloblastoma Growth, Not Start
08 May 2025 02:46 GMT
… , particularly within subgroup V medulloblastomas. Patients exhibiting MYC-amplified … ecosystems. Subject of Research: Medulloblastoma tumor heterogeneity and oncogene … Title: Oncogene aberrations drive medulloblastoma progression, not initiation Article …
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Raising awareness for a cure for Medulloblastoma
03 May 2025 00:34 GMT