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A Review of Retinopathy Of Prematurity
13 Dec 2025 07:54 GMT
… inhibiting VEGF, a key mediator of pathological retinal neovascularization … Initial treatment with these drugs may help preserve the … and received orphan drug designation for treatment … Europe.
Razumab (Intas Pharmaceuticals) is a ranibizumab biosimilar …
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<![CDATA[Phase 2 Nemolizumab Trial Opens for CPUO]]>
12 Dec 2025 15:18 GMT
This week, Galderma announced the first patient enrollment in its phase II study evaluating nemolizumab for the treatment of Chronic Pruritus of Unknown Origin (CPUO), a condition that remains both highly prevalent and poorly understood.1 The initial …
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Plasma MRGPRX2 Correlates with Severity of Artemisia-Induced Allergic Rhinitis, Particularly in IgE-Negative Patients: A Cross-Sectional Study
12 Dec 2025 16:33 GMT
… emerged as a key mediator of non-IgE-mediated hypersensitivity … functions as a key mediator linking MC activation to sensory … potential as targets for future drugs. Pharmacol Ther. 2022;238. doi … procedure for diagnosis. Acta Pharmacol Sin. 2013;34(10): …
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Brain resilience science reshapes psychiatry from treating illness to building strength
11 Dec 2025 15:30 GMT
… brain reward circuits during chronic drug exposure and stress, fundamentally altering … this protein as a crucial mediator of addiction vulnerability.
This interview … behavioral function despite exposure to drugs or stress. These resilient individuals …
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InflaRx Announces International Nonproprietary Name of “Izicopan” for INF904
11 Dec 2025 12:30 GMT
… a variety of metabolites and drugs, including glucocorticoids. Reported results from … per day for 14 days. Pharmacokinetic / pharmacodynamic data support the best-in … . C5a is a powerful inflammatory mediator involved in the progression of …
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<![CDATA[Celldex Advances Barzolvolimab into Phase 3 for Cold Urticaria and Symptomatic Dermographism]]>
09 Dec 2025 18:32 GMT
… immunoglobulin E (IgE) levels. The drug was also well-tolerated with … drug is designed to address disease pathophysiology upstream of symptom-mediator release …
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Study Reveals Surprisingly Obvious Reason Why Exercise Reduces Cancer Risk
09 Dec 2025 02:33 GMT
There's a lot of evidence that more exercise helps reduce cancer risk – but why are the two connected?
According to a new mouse study, it may be down to a metabolic shift that appears to give muscle cells more fuel to burn, while 'starving' …
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New Hypertension publication underscores aprocitentan’s potential in managing hypertension patients with CKD
10 Dec 2025 06:00 GMT
… tried more than four antihypertensive drugs, aprocitentan delivered significant blood … and vascular remodeling, and mediator of aldosterone and catecholamine release … Investor & Media Relations
Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 …
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Time-Weighted Cumulative High-Sensitivity C-Reactive Protein and Risk of Cardiac Conduction Block: Findings from a Prospective Cohort
13 Dec 2025 15:27 GMT
… inflammation but also an important mediator, promoting inflammation through the TLR4 … practice (such as initiating targeted drug therapies), but they provide an … ;CCR2 and phenotype switching. Acta Pharmacol Sin. 2024;45(5):959 …
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Pyrazoline B Induces Oxidative Stress Mediated Toxicity, Cell Cycle Arrest, and Caspase-Independent Apoptosis in BT-474 Human Breast Cancer Cells
13 Dec 2025 10:08 GMT
… is designed to evaluate the pharmacokinetics, drug-likeness, and medicinal chemistry properties … #47;AKT pathway, a known mediator of Cyclin D1 expression. Pyrazoline … free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry …