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SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model and its catalytic activity is regulated by histone acetylation
09 Jul 2025 18:24 GMT
… SETD2 deletion accelerates KRASG12C-driven lung cancer pathogenesis in vivo
Several elegant … .SETD2 ablation promotes KRASG12C-driven lung tumorigenesis in vivo.
A, Schematic … weight were checked daily.
Histology and immunohistochemistry
Tissue specimens were …
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Cizzle Bio Submits NIH Grant Proposal with Premier Research Institutions to Advance Biomarker Blood Test for Lung Cancer
09 Jul 2025 12:55 GMT
… oncology — detecting lung cancer before symptoms appear. Lung cancer is the leading … assess detection accuracy across different lung cancer histological subtypes. A key objective … with treating late-stage lung cancer, an important consideration for …
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Steroid Use During ICI Treatment Lessens Effectiveness in Patients With NSCLC
09 Jul 2025 20:03 GMT
… with non-small cell lung cancer (NSCLC) to shrink … eg, smoking history, tumor histology, performance status) can provide … in Non–Small Cell Lung Cancer Patients. Cancer Res Commun … Sciences. Common medication for lung cancer symptoms found to limit …
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FDA Grants Orphan Drug Designation to ADRX-0405 for Gastric Cancer
09 Jul 2025 20:24 GMT
… cancer (CRPC), non–small cell lung cancer (NSCLC), and gastric cancer.
… portion, eligible patients had histologically confirmed advanced solid tumors including … portion, eligible patients had histologically confirmed prostate adenocarcinoma identified to …
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Anti-Angiogenesis Plus ICIs, Chemo Improve Frontline Efficacy in ES-SCLC
09 Jul 2025 20:24 GMT
… untreated extensive-stage small cell lung cancer (ES-SCLC), according to a … trials that included patients with histologically or cytologically confirmed ES-SCLC … for extensive-stage small-cell lung cancer: a network meta-analysis. Ther …
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Clinical Features of Patients with Tropheryma Whipplei Detected in Lower Respiratory Tract Samples in China
09 Jul 2025 13:50 GMT
… duodenal biopsy, with histological examination revealing pathognomonic findings … nonspecific pleuritis. The histological features are consistent with … Case Report. Chin J Lung Cancer. 2023;26(7):553 … D, Jin J. Lung cancer patient with Tropheryma whipplei and …
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The Prognostic Value of Combined Systemic Immune-Inflammatory Index (SII) and Prognostic Nutritional Index (PNI) in Solid Tumor
08 Jul 2025 10:35 GMT
… various malignancies, including lung cancer,16 breast cancer17 and … criteria were applied: histologically or cytologically confirmed stage … non-small-cell lung cancer patients receiving adjuvant … advanced non-small cell lung cancer patients receiving platinum- …
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Noninvasive ultrasound targeted modulation of calcium influx in splenic immunocytes potentiates antineoplastic immunity attenuating hepatocellular carcinoma proliferation
08 Jul 2025 03:33 GMT
… tissue damage, the histologic sections were stained with … , meningiomas, colon cancer, lung cancer, and particularly HCC, by … absence of toxicity. Histological sections showed preserved tissue … 104–108]. Additionally, histological assessment through HE and …
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Dr Azenkot on Dupilumab Plus Cemiplimab in Early-Stage, Resectable NSCLC
08 Jul 2025 02:41 GMT
… -stage, resectable non–small cell lung cancer (NSCLC). Notably, the design of … signaling by dupilumab can reduce lung tumor burden by activating dendritic cells … (≥ T1b) resectable NSCLC of any histology. Patients are also required to …
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Biomarker and Prognostic Value of Super-ARMS Detection for EGFR Mutation in Advanced NSCLC
07 Jul 2025 20:59 GMT
… mutant patients with histologically confirmed NSCLC … , Non-Small Cell Lung Cancer; CEA, Carcinoembryonic Antigen … lung cancer: a medicare claims analysis. Clin Lung Cancer. … lung cancer (NSCLC) patients with baseline tissue EGFR mutations. Transl Lung Cancer …