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Fifteen-Month Outcomes of Preservative-Free Latanoprost Cationic Emulsion in Open-Angle Glaucoma and Ocular Hypertension: Phase III Open-Label Extension of a Randomized Trial
12 Dec 2025 16:33 GMT
… preservative-free latanoprost eye drop emulsion treatment versus preserved latanoprost.51 … therapy or an oral drug for glaucoma (within 6 … ≥1 dose of study medication and had ≥1 post … reflects previous long-term trials examining latanoprost monotherapy in OAG…
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Survey of Drugs Induced Skin Pigmentation (Hyper and Hypo Pigmentation)
17 Nov 2025 10:30 GMT
… patients receiving minocycline treatment. Early recognition can … trials to validate the causal relationship between drugs … FDA Adverse Event Reporting System; MC1R, Melanocortin-1 Receptor; MedDRA, Medical … with either latanoprost or bimatoprost therapy. …
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A Medical Therapy Update
10 Oct 2025 21:40 GMT
… have been FDA-approved for sustained release treatment.
Approved … trial.
• Glaucoma Evolute (Mati Therapeutics) is a latanoprost- … of nicotinamide outside clinical trials. Without routine liver … .pharmaceutical-technology.com/news/spyglass-drug-delivery …
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Nicox’s NCX 470 Maintains Long-Term Efficacy in Phase 3 Denali Trial for Glaucoma and Ocular Hypertension
03 Oct 2025 07:43 GMT
… ;s potential as a future treatment option.
Confirmed Long-Term Efficacy … trial compared NCX 470, a nitric oxide–donating bimatoprost analog, with latanoprost … -lowering efficacy consistent with prior trials and maintained a favorable safety …
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Nicox’s NCX 470 Demonstrates Sustained Efficacy through 12 Months in Denali Clinical Trial with no new Safety Observations
02 Oct 2025 05:30 GMT
… additional safety signals seen.
New Drug Applications (NDAs) for NCX … double-masked, parallel group trial that evaluated the safety and … , 0.1% compared to latanoprost ophthalmic solution, 0.005% … U.S. and China. Latanoprost is the most widely prescribed …
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Qlaris Bio Doses First Patient in Phase 2 Nightingale Trial for Normal Tension Glaucoma
27 Aug 2025 07:50 GMT
… IOP achievable with conventional treatments. Since patients with NTG … National University College of Medicine and lead investigator of … .S.-based Phase 2 trials, Osprey and Apteryx, which … monotherapy and in combination with latanoprost.
“The initiation of the …
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First patient dosed in Qlaris Bio's phase 2 Nightingale clinical trial for QLS-111
26 Aug 2025 23:23 GMT
… National University College of Medicine and lead investigator … Osprey and Apteryx clinical trials. Both trials “demonstrated promising safety … latanoprost,” the release stated.1
Osprey and Apteryx trial … in development for the treatment of primary open-angle …
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Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment
25 Aug 2025 14:05 GMT
… the Food and Drug Administration (FDA) for legal treatment of AGA,4 … significant advances in the medical treatment of AGA in recent … with finasteride in terms of doctors’ satisfaction, hair density, and … a 24-week topical treatment by latanoprost 0.1% on hair …
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Nicox releases topline data from phase 3 Denali trial of NCX 470 in open-angle glaucoma or ocular hypertension patients
22 Aug 2025 02:09 GMT
… regulatory requirements to support new drug application (NDA) submissions of … an NDA to the US FDA in the first half of … . 9.2% of latanoprost 0.005% patients. During the trial, 10.1% … ’s potential as an important treatment option for glaucoma patients.”
Nicox …
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Maximum Tolerated Medical Therapy for Glaucoma: Fixed-Dose Combinations of Timolol, Dorzolamide, Brimonidine with Latanoprost Versus Timolol, Dorzolamide with Latanoprost
21 Aug 2025 21:57 GMT
… ’s maximal medical therapy regimen of three drugs daily instillations … and patients treated with antidepressants that affect noradrenergic transmission. … was added to the treatment with latanoprost), or if a … missing data in clinical trials. J Biopharm Stat. …