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Advances of Drug-Loaded Microsphere Technology for Targeted Immunotherapy Against Prostate Cancer
19 Sep 2025 16:43 GMT
… resists conventional treatments. Microcatheter-assisted drug-loaded microspheres … drug concentrations.8 Lapatinib lipid microspheres enhance drug … doi:10.3390/pharmaceutics14020359.
10. Nicoletti R, … al. Intradermal DNA vaccination combined with dual …
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Eribulin plus Pyrotinib in Trastuzumab-Resistant, HER2-Positive Advanced Breast Cancer: A Single-Arm, Multicenter Phase II Trial (EPIC Trial)
17 Sep 2025 17:44 GMT
… months in clinical trials.2,3 Despite this … -DXd), an antibody-drug conjugate linking trastuzumab to … chemotherapy (eg, vinorelbine), lapatinib/capecitabine combinations, or … treatment and any medical condition deemed to compromise patient safety or trial …
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Investigation of Thrombocytopenia Associated with Trastuzumab Emtansine Treatment in Breast Cancer: A Retrospective Study in a Chinese Population
04 Sep 2025 21:52 GMT
… recent years, antibody-drug conjugates (ADCs) have … treatment combinations, such as trastuzumab plus docetaxel2 or lapatinib … included demographic characteristics, medical history, laboratory results, … controlled trials. For example, the EMILIA trial reported …
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Determination of 5-Fluorouracil in Dried Blood Spots for Therapeutic Drug Monitoring and Adverse Event Assessment in Breast Cancer Patients
29 Aug 2025 09:00 GMT
… anticancer therapy such as lapatinib, anastrozole, and letrozole … traditional Chinese medicines for colorectal cancer treatment. Integr … practice: analysis of drugs and pharmaceutical formulations. Futur J … 47;/www.fda.gov/vaccines-blood-biologics…
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Lapatinib and NNC 55-0396 Boost Gastric Cancer Fight
07 Aug 2025 14:20 GMT
… biomarker-driven precision medicine. Given the heterogeneous … for rigorous clinical trials to validate safety, … repurposing existing drugs—such as lapatinib, already approved … adenocarcinoma researchgastric cancer treatment advancementsimproving survival rates …
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drugs that target the HER2 protein
10 Jul 2025 20:31 GMT
… inhibitors.
Lapatinib (Tykerb): This drug is a pill taken daily. Lapatinib is used … medicines for high blood pressure.
Because these drugs can cause heart damage, doctors … before starting treatment with this drug.
This drug is taken as pills, typically twice …
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What You Need to Know About Breast Cancer Chemotherapy Pills
01 Jul 2025 14:46 GMT
… treatment plan:
chemotherapy pills
antihormone pills
targeted therapy (precision medicine) pills … like warfarin, your doctor may need to … is also available in pill form.
Common side … drugs, like lapatinib (Tykerb) and tucatinib (Tukysa), both oral medications …
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Zanidatamab Plus Chemotherapy Shows Promising Anti-Tumor Activity in Treatment of HER2-Mutated Breast Cancer
21 May 2025 23:08 GMT
Zanidatamab (Ziihera; Jazz Pharmaceuticals, Inc) plus chemotherapy … a treatment for HER2-mutated BCs. The trial is … (80%; Perjeta; Genentech, Roche), lapatinib (24%; Tykerb; Novartis), trastuzumab … (7%; Nerlynx; Puma Biotechnology). Patients with HER2-low …
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Study Links PAK5 to Poor Outcomes and Drug Resistance in HER2-Positive Breast Cancer
23 Apr 2025 17:13 GMT
… . Innovative HER2-targeted treatments, such as the antibody drug conjugate T-DM1 … approved by the FDA in 2019 for the adjuvant treatment of patients … responsive to both trastuzumab and lapatinib (Tykerb; GSK), another targeted therapy …
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107 Neratinib-Based Combination Treatments for Patients With HER2-Positive Breast Cancer Brain Metastases
10 Apr 2025 01:44 GMT
… HER2+ BCBM, focusing on prospective trials reporting CNS outcomes. CNS-specific … + BCBM trial, assessed neratinib combinations in patients with no prior lapatinib (cohort … with other FDA-approved drugs represents a promising approach to the treatment of …