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The Effect of Ozone on Kidney and Liver Tissues in the Treatment of Sepsis Caused by Cecal Perforation in Diabetic Mice
18 Dec 2025 20:25 GMT
… .28 Despite current treatment approaches, morbidity and … V. OZONE: A New Medical Drug. Springer Netherlands; 2010.
13 … treatment of sepsis in rats with cecal perforation. Medicina. … Irbesartan attenuates sepsis-induced renal injury in mice models. J Pharmaceut …
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Renalys Pharma reaches Japan PMDA agreement on phase III trials of sparsentan for FSGS and Alport syndrome
20 Oct 2025 12:34 GMT
… an agreement with the Pharmaceuticals and Medical Devices Agency (PMDA) … two phase III clinical trials of sparsentan in Japan … profile compared with active control irbesartan. In Europe, it … new drug application (sNDA) for Filspari for the treatment of …
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Renalys Pharma Reaches Japan PMDA Agreement on Phase III Clinical Trials of Sparsentan for Focal Segmental Glomerulosclerosis (FSGS) and Alport Syndrome (AS)
17 Oct 2025 06:44 GMT
… an agreement with the Pharmaceuticals and Medical Devices Agency (PMDA) … profile compared with active control irbesartan. In Europe, it … new drug application (sNDA) for FILSPARI® for the treatment of … -on-phase-iii-clinical-trials-of-sparsentan-for-focal …
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FULL LIST: Flagyl, Artemether-Lumefantrine among 101 drugs delisted by NAFDAC
30 Sep 2025 20:15 GMT
… Agency for Food and Drug Administration and Control ( … formulations) and cough treatments to vaccines (such as … injectables (like Norditropin), diabetes medicines (Januvia/Janumet), …
B4-2317
Hydrochlorothiazide + Irbesartan
Sanofi Aventis Nigeria Ltd …
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FDA Approves REMS Modification for Sparsentan in IgA Nephropathy
28 Aug 2025 20:26 GMT
… phase 3 PROTECT clinical trial (NCT03762850)2, a randomized … review with the FDA, with a Prescription Drug User Fee … medicine indicated for FSGS.
“[Sparsentan] is becoming a foundational treatment … safety of sparsentan versus irbesartan in patients with IgA …
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Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
12 Aug 2025 12:14 GMT
… treatment with compound dendrobium iron combined with irbesartan … were provided by Hanhui Pharmaceutical Co., LTD.; Amlodipine … from Chengdu Remifensi Biotechnology Co., LTD.
Chromatographic … herbal remedies and antihypertensive Western medications can …
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Old Drugs, New Hope: Review Explores Repurposing Medicines for Rare Diseases
10 Jun 2025 09:03 GMT
… new drug development, treatment options remain severely limited.
In conversation with Medical … (ARBs) like losartan and irbesartan—typically prescribed for hypertension—in … governed clinical trials. If international regulatory bodies like the FDA or …
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NICE Approves Sparsentan for Kidney Disease Treatment
28 May 2025 15:53 GMT
… effectively than standard treatment. The drug may also better … -controlled, phase 3 trial included patients aged 18 … irbesartan group.
The researchers concluded that treatment with sparsentan vs maximally titrated irbesartan … a retired NHS doctor. A well-known …
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FDA Accepts Sparsentan (Filspari) sNDA for Focal Segmental Glomerulosclerosis
15 May 2025 22:45 GMT
… , the FDA has assigned a Prescription Drug User Fee … daily, oral medication the first non-immunosuppressive treatment for preventing … consistent across all clinical trials conducted to date … active control, irbesartan, including no drug-induced liver injury …
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England's NICE Recommends FILSPARI® (Sparsentan) As A Treatment Option For Iga Nephropathy
23 May 2025 08:49 GMT
… of diagnosis.11
Current medical treatment guidelines by KDIGO … , manufacturing and marketing pharmaceutical products for precision healthcare … , active-controlled clinical trial evaluating the safety and … for irbesartan-treated patients (n=202).4,17 Treatment …