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Annexin A: Cell Death, Inflammation, and Translational Medicine
26 Apr 2025 05:08 GMT
… clinically approved drugs (eg, sorafenib, sulfasalazine, statins, and … the development of pharmaceutical formulations, which … translational medicine approach to inflammatory disease treatment, which … al. ZBP1 mediates interferon-induced necroptosis. Cell …
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Itaconate Regulates Immunity by Blocking Peroxiredoxin 5
30 Apr 2025 04:51 GMT
… a second messenger amplifying interferon-beta production. This mechanism elucidates … this balance could revolutionize treatments for viral infections and … metabolitesitaconate and inflammatory disease treatmentitaconate and peroxiredoxin 5macrophage activation …
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Measles Virus-Based Genetic Modifications: Progress in Hematological Malignancy Treatment
24 Apr 2025 16:10 GMT
… still experience relapse or drug resistance, resulting in …
Table 2 Clinical Trials of Treatment for Hematological Malignancies … models of glioblastoma. Nat Biotechnol. 2018. doi:10. … Oncolytic measles viruses encoding interferon beta and the thyroidal sodium …
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Existing MS Drug Revives Immune Cells, Offering Hope for Sepsis Patients
22 Apr 2025 09:29 GMT
… die. For a long time, doctors believed that sepsis-related mortality … us with clues for potential treatments that could revive the body … ;
Medication activates immune cells
The researchers then added an existing drug, interferon beta, to …
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HEALTH – A drug available on the market gives hope to patients with sepsis
21 Apr 2025 07:54 GMT
… with valuable data to develop treatments capable of strengthening the body … interferon beta, a commercially available drug, to the monocytes in the laboratory.
This medication … is used in the treatment of multiple sclerosis …
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Existing drug shows potential to revive immune cells in sepsis patients
18 Apr 2025 17:09 GMT
… die. For a long time, doctors believed that sepsis-related mortality … us with clues for potential treatments that could revive the body … ;
Medication activates immune cells
The researchers then added an existing drug, interferon beta, to …
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Human medicines European public assessment report (EPAR): Extavia, interferon beta-1b, Date of authorisation: 20/05/2008, Revision: 26, Status: Authorised
02 Apr 2025 22:54 GMT
Extavia was studied over a two-year period in 338 patients with relapsing remitting MS who were able to walk unaided, where its effectiveness was compared with placebo (a dummy treatment). Extavia was more effective than placebo in reducing the number of …
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AAN 2025: Precision Medicine and Pharmacogenomics in Neurological Care
09 Apr 2025 23:38 GMT
… individual patient. Precision medicine involves delivering targeted … established “trial and error” method of treatment and instead … migraine medication, and CYP enzymes metabolize migraine drugs. Robust … DMTs) in MS is interferon beta (IFNβ). Approximately 20% …
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Recent Advances of Type I Interferon on the Regulation of Immune Cells and the Treatment of Systemic Lupus Erythematosus
29 Mar 2025 17:26 GMT
… distinct groups: interferon I, interferon II, and interferon III (Table … Drug Administration (FDA) and the European Union for the treatment … diseases. Phase II clinical trials have been completed for … Phase 2b randomised clinical trial in patients with …
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Immune and Metabolic Reprogramming Induced by Paclitaxel, Capecitabine and Eribulin in Breast Cancer: Insights into Therapeutic Targets
28 Apr 2025 17:19 GMT
… their metabolic profiles and drug treatment. Volcano plots of differentially … cancer: a randomized clinical trial. JAMA Oncol. 2020; … metabolic reprogramming necessary for interferon production in human … of in vitro cytotoxicity trials. Nutrients. 2023;15 …