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Kura doses first subjects in trial of ziftomenib for advanced GIST
29 Apr 2025 13:18 GMT
… ziftomenib in conjunction with imatinib in the adult population … high unmet medical needs.
Kura Oncology chief medical officer … menin inhibitors for the treatment of cancer.
“Approximately … KOMET-001 trial, the US Food and Drug Administration (FDA) granted …
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Kura Oncology Announces First Patients Dosed in Phase 1 Combination Trial of Ziftomenib for the Treatment of Advanced GIST
28 Apr 2025 11:30 GMT
… antitumor activity in imatinib-sensitive and imatinib-resistant GIST … promise of precision medicines for the treatment of cancer, … & Early Phase Drug Development Specialist at Memorial … 001 clinical trial. Additional information about clinical trials for …
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Advances in the treatment of pulmonary arterial hypertension
25 Apr 2025 00:38 GMT
… been approved by the FDA for treating PAH. … in clinical trials evaluating various formulations of imatinib, additional … .37
Combination Treatments and Personalized Medicine
The AMBITION trial (NCT01178073), … In a clinical trial of the drug (NCT02279160; Safety …
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Aurobindo Pharma arm Eugia Pharma Specialities gets USFDA nod for cancer drug
23 Apr 2025 11:45 GMT
… Tablets is indicated for the treatment of newly diagnosed adults with … intolerance to prior therapy including imatinib, adults with Ph+ acute lymphoblastic … thrombosis drug Rivaroxaban
Aurobindo Pharma Limited is an integrated global pharmaceutical company …
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SIRT With 90Y Resin Microspheres Provides Benefit in GIST Liver Metastases
29 Apr 2025 20:25 GMT
… and Thoracic Surgery, University Medical Center Mannheim, Medical Faculty Mannheim – Heidelberg University … number of prior treatments before SIRT was three, including imatinib, sunitinib and …
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Utilizing Physiologically Based Pharmacokinetic Models to Support Rational Medication in Chinese Elderly Population
21 Apr 2025 19:24 GMT
… first-in-human trials, investigation of drug–drug interaction, assessment … moclobemide in the antidepressant indication is 300– … and their consequences for drug treatment in old age. … mexiletine, ethinylestradiol, and caffeine. Pharmaceutics. 2020;12(12):1191. …
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US-India trade talks: Ensure medicines remain affordable
20 Apr 2025 15:46 GMT
… is demonstrated. For example, imatinib mesylate (used to treat … medicines. For instance, semaglutide (Ozempic) is a patented drug … enables pharmaceutical firms to produce and sell biosimilar drugs at … exclusivity on test trial data of drugs. Data exclusivity …
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Affordable Medicine: Has Indian Patents Act Succeeded?
17 Apr 2025 07:09 GMT
… introducing product patents in pharmaceuticals, alongside the existing … clarity regarding any major remedy to address cases … domestic pharmaceutical companies could provide affordable generic medicines as … of its anti-cancer drug, imatinib mesylate in 1998.** …
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Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing
17 Apr 2025 02:48 GMT
… via immunohistochemistry.
Three existing drugs (TG100801, Hydrochlorothiazide, and Imatinib) were identified as … = 0.017).
Three drugs (TG100801, Hydrochlorothiazide, and Imatinib) were flagged for their …
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1 in 6 patients in phase 2 cancer trials receive therapies that are ultimately approved
15 Apr 2025 15:09 GMT
… , MSc, PhD candidate in experimental medicine at McGill University — aimed to … in phase 2 trials to receive an FDA-approved treatment served as the … 1 trial that you’re to get access to a drug like imatinib …