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Intra- and Peritumoral Radiomic Signatures on CECT: Prediction of Aggressive Hepatocellular Carcinoma Subtypes and 2-Year Recurrence
20 Dec 2025 13:25 GMT
… hepatocellular carcinoma; NPHCC, non-proliferative hepatocellular carcinoma; MTM-HCC, macrotrabecular-massive hepatocellular carcinoma; … pharmacological, immunological, and CAR-T-cell approaches in the treatment of hepatocellular carcinoma. Drug …
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Predicting the Occurrence of Cachexia in Patients with BCLC Stage B/C Hepatocellular Carcinoma Receiving Systemic Therapy: A Nomogram Based on Common Clinical Parameters
20 Dec 2025 08:31 GMT
… role in nutrient metabolism, hepatocellular carcinoma (HCC) is one of … (OS). Yet, cachexia development remains a primary therapeutic … adjustments due to poor medication adherence during follow-up … -based approaches to treatment. Curr Treat Options Oncol. 2010 …
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Integrative Spatial Transcriptomics and Experimental Validation Reveal UBC-Mediated EMT Associated with Immune Evasion in Hepatocellular Carcinoma
18 Dec 2025 20:24 GMT
… Epidemiological data indicate that hepatocellular carcinoma (HCC) remains a major … high recurrence and limited treatment efficacy. A major … utilized to reconstruct developmental trajectories and infer … metastatic potential, and drug resistance.24,25 However, …
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<![CDATA[BGB-B2033 Gains FDA Fast Track Status in Advanced HCC]]>
19 Dec 2025 19:17 GMT
… the treatment of advanced hepatocellular carcinoma (HCC).1
As … facilitate clinical development as it progresses … safety, tolerability, pharmacokinetics, and preliminary … FDA fast track designation for BGB-B2033 as treatment for hepatocellular carcinoma …
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BeOne Medicines Granted U.S. FDA Fast Track Designation for BGB-B2033 as Treatment for Hepatocellular Carcinoma
18 Dec 2025 11:12 GMT
… unmet medical need in HCC; BeOne’s clinical development plan for BGB … on third parties to conduct drug development, manufacturing, commercialization, and other … obtaining regulatory approvals and commercializing pharmaceutical products and its ability to …
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<![CDATA[Updates in Treatment of Unresectable Hepatocellular Carcinoma ]]>
18 Dec 2025 03:03 GMT
… progressed or developed intolerance to the medication. Additionally, … pharmacists are well positioned to screen for drug-drug interactions (DDIs) with HCC treatment … first line treatment in participants with advanced hepatocellular carcinoma (HCC) (SIERRA). …
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The Combined ALBI-FIB-4 Score for Prognostic Stratification in Hepatocellular Carcinoma: A Single Center Retrospective Study
18 Dec 2025 00:28 GMT
… Hepatocellular carcinoma (HCC) is a primary malignancy of the liver that most commonly develops … composite score rather than treat these parameters as … receiving systemic treatment.
Conventional prognostic systems for hepatocellular carcinoma, such as …
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Transcatheter Arterial Chemoembolization May Be Selectively Indicated as Postoperative Adjuvant Therapy for Hepatocellular Carcinoma Patients with Microvascular Invasion
18 Dec 2025 00:28 GMT
… need to develop novel diagnostic … , Sarkar D. Hepatocellular carcinoma (HCC): epidemiology, etiology … hepatocellular carcinoma with microvascular invasion: a randomised controlled trial … outcome of hepatocellular carcinoma after treatment of transarterial …
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The TBS-PALB-NLR Triad: A Novel Preoperative Prognostic System Guiding Therapeutic Decision-Making in Unresectable HCC Treated with Transarterial Chemoembolization
19 Dec 2025 14:01 GMT
Introduction
Hepatocellular carcinoma (HCC) is a highly heterogeneous … propose calculating TBS by treating tumor size and number … utilizes the TBS, which treats tumor size and number … assisting in the development of personalized treatment strategies based on …
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<![CDATA[FDA Grants Fast Track Designation to GPC3x4-1BB Bispecific Antibody in HCC]]>
18 Dec 2025 21:37 GMT
… treatment for adult patients with hepatocellular carcinoma (HCC … developer, … trial (NCT06427941), which is evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics … FDA fast track designation for BGB-B2033 as treatment for hepatocellular carcinoma …
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