-
Terns drug shows potential to challenge Novartis’ blockbuster leukemia treatment
08 Dec 2025 21:04 GMT
… known as chronic myeloid leukemia.
According to results presented … as Scemblix or another Novartis medicine, Gleevec, as well as … with Scemblix and another CML drug, Iclusig — have occurred. … in CML. Early drugs like Gleevec worked by blocking the …
-
<![CDATA[Essential Insights on GIST and Gleevec for Patients]]>
05 Dec 2025 21:19 GMT
… by the National Cancer Instittue on its website, Gleevec works by blocking … -down-gastrointestinal-stromal-tumor-basics
“Gleevec,” National Cancer Institute; https:/… /dictionaries/cancer-terms/def/gleevec
Transcript has been …
-
David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
01 Dec 2025 12:08 GMT
… viruses that cause cancer contain an enzyme … discovered and characterized several cancer-causing genes, including … kinase in Abelson murine leukemia virus. The mammalian … leukaemia in humans, a cancer now treated successfully with the kinase inhibitor Gleevec …
-
[Interview] 'Adults with ALL need the most effective drugs first’: Hematologist warns of widening treatment gap'
21 Nov 2025 06:42 GMT
Acute lymphoblastic leukemia (ALL) is a blood cancer that can affect … can tolerate high-dose anticancer drugs, but older adults cannot, … A: Using the most effective drugs first. Ponatinib, a third- … , but only first-generation Glivec is reimbursed, for just …
-
India’s drug industry saved the world once. Can it do it again?
19 Nov 2025 13:40 GMT
… factory making a critical cancer drug shut down in 2023 … 2006 from Novartis, the Swiss drug maker behind the cancer drug Glivec. It … Indian-made drugs.
Activists protest outside Novartis’s Mumbai … 2024, Cosentyx, a drug from Novartis that treats psoriasis and …
-
How Targeted Therapy Is Changing Cancer Treatment
14 Nov 2025 00:19 GMT
… therapy—is transforming modern cancer treatment, generating drugs that are more effective … . This landmark drug, called imitanib (brand name Gleevec), turned chronic myeloid leukemia (CML … against certain types of breast cancer. Drugs that inhibit B-Raf, a …
-
After a lackluster first drug launch, a new CEO is finding Geron’s commercial footing
12 Nov 2025 20:40 GMT
… first-quarter demand for the drug “relatively flat.”
Geron also … at Novartis, where he was global lead for Gleevec and … 39; lives in chronic myelogenous leukemia [and] was on the … even better [National Comprehensive Cancer Network] guideline endorsement. We …
-
<![CDATA[FDA Approves Abbreviated NDA for Dasatinib Tablets in Leukemia Indications]]>
08 Nov 2025 01:03 GMT
… approval for an abbreviated new drug application (ANDA) for generic dasatinib … chromosome (Ph)–positive chronic myeloid leukemia (CML) in chronic phase
Adult … , including imatinib (Gleevec)
Adult patients with Ph-positive acute lymphoblastic leukemia (ALL …
-
<![CDATA[Correlation Observed Between Leukemia Stem Cells and Response in CML]]>
04 Nov 2025 15:26 GMT
… patients with chronic myeloid leukemia (CML). The findings … patients began treatment with imatinib (Gleevec), 30% (n = 72) … role of peripheral blood leukemia stem cells at … myeloid leukemia patients: Final results of prospective FLOWERS study. Cancer. …
-
<![CDATA[Accelerated Approval of Cancer Drugs: Benefit or Burden?]]>
30 Oct 2025 00:52 GMT
… is imatinib (Gleevec; Novartis Pharmaceuticals Corporation) for chronic myelogenous leukemia (CML) and … the survival benefit of new cancer drugs: a discrete choice experiment. … of the clinical benefit of cancer drugs receiving accelerated approval. JAMA …