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<![CDATA[Erdafitinib Is Safe and Shows Preliminary Efficacy in F3T3 Fusion+ Glioma]]>
23 Nov 2025 07:24 GMT
… in gliomas; these fusions are also retained in recurrent glioblastoma. … efficacy of erdafitinib in glioblastoma?
de la Fuente highlighted … grade 4 F3T3 fusion–positive glioblastoma. This patient underwent biopsy … , WHO grade 4 glioblastoma that was MGMT promoter …
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NSUN7 Modulates Glioblastoma Stemness via m5C CircNTRK2
22 Nov 2025 23:47 GMT
… specifically target these pathways in glioblastoma.
The community eagerly anticipates follow … circNTRK2 regulates stemness properties of glioblastoma cells by activating STK31.
… stem cell propertiesNSUN7 role in glioblastomaRNA biology in brain tumorsRNA …
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<![CDATA[Dr Lombardi on Phase 1 Data With Regorafenib Plus Temozolomide and CRT for Newly Diagnosed Glioblastoma]]>
22 Nov 2025 19:03 GMT
… , MGMT-methylated, IDH wild-type glioblastoma.
Lombardi explained that the trial …
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<![CDATA[B7-H3 CAR T-Cell Therapy Shows Acceptable Safety in Recurrent Glioblastoma]]>
22 Nov 2025 16:02 GMT
… ?
Currently patients with glioblastoma have a median survival … with diffuse intrinsic pontine glioma.
What was the … therapy in patients with glioblastoma?
This dose-escalation … with histologically confirmed recurrent glioblastoma, a Karnofsky performance score …
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<![CDATA[Gomekli Shows Early Activity in Pediatric Low Grade Glioma]]>
22 Nov 2025 16:02 GMT
… Assessment in Pediatric Low-Grade Glioma radiological response criteria was 87% … included pilocytic astrocytoma (83%), diffuse glioma (6%), diffuse leptomeningeal glioneuronal tumor … recurrent/progressive low-grade glioma: update from the SJ901 ( …
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<![CDATA[Voranigo Plus Temodar Found to Be Safe in Patients With IDH1/2+ Glioma]]>
22 Nov 2025 16:02 GMT
… with IDH1- or IDH2-mutant glioma, the treatment combination of … in IDH1/2-mutated glioma?
Although Voranigo is approved … with higher-grade, more aggressive gliomas.
As such, de la … [IDH1/2-mutant] gliomas while controlling more rapidly proliferative …
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Intranasal nanomedicine shows promise against glioblastoma
22 Nov 2025 15:11 GMT
… 39;t capable of curing glioblastomas without reinforcement from other therapeutic … , more effective treatments for glioblastoma and potentially other immune treatment … spherical nucleic acids reprogram the glioblastoma immune microenvironment and promote …
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<![CDATA[B7-H3–Directed CAR T-Cell Therapy Has Acceptable Safety Profile in Recurrent Glioblastoma]]>
22 Nov 2025 12:44 GMT
… infusion in patients with recurrent glioblastoma, meeting the primary safety objective … patients with diffuse intrinsic pontine glioma.2
What was the design … age with histologically confirmed recurrent glioblastoma, a Karnofsky performance score of …
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<![CDATA[Effective Early Treatments Needed in Glioma, Real-World Data Finds]]>
22 Nov 2025 09:43 GMT
… slow-growing IDH-mutant gliomas, researchers have reported — … patients with [IDH]-mutated glioma were managed with observation, … with WHO grade 3 glioma also underwent observation.”
Researchers … patterns in IDH-mutated glioma: Implications for targeted therapy …
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<![CDATA[Early Real-World Uptake of Voranigo in Patients With IDH-Mutant Glioma]]>
22 Nov 2025 09:43 GMT
… with isocitrate dehydrogenase–mutated glioma, including both newly diagnosed … 50% were diagnosed with glioma one to five years … they had a confirmed glioma diagnosis, underwent surgery before … either surgery only or glioma diagnosis only revealed results …