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VIDEO: Questions remain regarding use of giredestrant, oral SERDs for breast cancer
21 Dec 2025 15:32 GMT
… trial, presented at San Antonio Breast Cancer Symposium, and what questions and … giredestrant in breast cancer.
The phase 3 lidERA trial compared giredestrant (Genentech, Roche … endocrine therapy for early-stage breast cancer.”
Sources/Disclosures
Healio …
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VIDEO: Adding tucatinib to maintenance therapy a ‘great option’ in metastatic breast cancer
20 Dec 2025 15:14 GMT
… outcomes in HER2-positive metastatic breast cancer.
Results of the trial, … Herceptin, Genentech) and pertuzumab (Perjeta, Genentech), were presented at San Antonio Breast Cancer Symposium … any patient with HER2-positive breast cancer, but particularly in that …
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Enhertu wins FDA approval as initial therapy for breast cancer
19 Dec 2025 10:05 GMT
… with advanced HER2-positive breast cancer confirmed through an FDA … s Perjeta, developed by Genentech, was first approved in … untreated HER2-positive metastatic breast cancer.
The FDA also cleared … with advanced HER2-positive breast cancer who had not …
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<![CDATA[1L Giredestrant Yields Improved IDFS vs ET in ER+/HER2– Breast Cancer]]>
18 Dec 2025 20:29 GMT
… IDFS excluding second primary non-breast cancer. Secondary end points included … Pharma/AstraZeneca, Eli Lilly, Genentech Inc., Gilead, Menarini, Merck, … III lidERA Breast Cancer trial. Presented at: 2025 San Antonio Breast Cancer Symposium; December …
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AstraZeneca, Daiichi Sankyo's breast cancer drug gets new FDA nod
15 Dec 2025 21:41 GMT
… treatment for HER2-positive breast cancer patients.
The new … s Perjeta, developed by Genentech, was first approved in … untreated HER2-positive metastatic breast cancer.
The FDA also cleared … patients with HER2-positive breast cancer eligible for treatment with …
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VIDEO: Tucatinib plus maintenance therapy delays metastatic breast cancer progression
15 Dec 2025 16:50 GMT
… and pertuzumab delayed metastatic breast cancer progression.
Tucatinib almost doubled … maintenance therapy delayed metastatic breast cancer progression for HER2-positive … (Perjeta, Genentech).
Results were presented at San Antonio Breast Cancer Symposium. …
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<![CDATA[SABCS 2025 Roundup: Advancing Therapy and Precision Care in Breast Cancer]]>
13 Dec 2025 22:52 GMT
… reshaping treatment paradigms across breast cancer subtypes. This year’s … foundational in HR+ metastatic breast cancer and provide clinicians with confidence … (Perjeta; Genentech) following induction therapy in metastatic HER2+ breast cancer. Results showed …
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<![CDATA[Cardiotoxicity Remains a Concern as Breast Cancer Survival Rates Improve: Eric H. Yang, MD]]>
12 Dec 2025 21:11 GMT
… ;Optimizing Cardiac Outcomes in Breast Cancer—The Next Chapter." … auto-generated.
Transcript
Which breast cancer therapies pose the greatest … maintenance or for advanced breast cancer, which are not … as bevacizumab or Avastin (Genentech), have also been …
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<![CDATA[ADCs in Breast Cancer: Shaping the Future of HER2- and TROP2-Targeted Therapy]]>
12 Dec 2025 06:07 GMT
… with HER2+ breast cancers across various disease … Genentech, Inc) in this setting for patients with HER2+ early breast cancer … breast cancer.
In heavily pretreated patients with early breast cancer … residual invasive breast cancer following neoadjuvant therapy …
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<![CDATA[Elacestrant-Based Combinations Show Efficacy, Safety in ER+, HER2-Negative Breast Cancer ]]>
12 Dec 2025 03:28 GMT
… positive, HER2-negative metastatic breast cancer, particularly those who received … all patients with metastatic breast cancer.”
Accordingly, Rugo and … Roche/AG/Genentech,Lilly, Merck, Novartis, … Roche/AG/Genentech, and Stemline Therapeutics.
…