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Lilly’s Oral SERD Wins FDA Go-Ahead for Breast Cancer
26 Sep 2025 12:58 GMT
… . Overall survival, something the FDA recently recommended be a primary … proliferation of cancer cells, while also sidestepping the treatment resistance typically … that giredestrant plus the chemotherapy drug everolimus significantly improved PFS in patients …
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Eli Lilly's oral SERD Inluriyo passes muster with FDA in breast cancer
26 Sep 2025 01:43 GMT
… therapies, often contributing to treatment resistance,” Komal Jhaveri, … phase 3 Ember-3 trial, which supported Inluriyo … with the FDA and presented at a medical meeting … everolimus, improved progression-free survival in ER-positive, HER2-negative breast cancer …
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<![CDATA[Breast Cancer Experts: Key ADC Developments and CDK 4/6 Inhibitor Updates Set to Dominate ESMO 2025]]>
25 Sep 2025 16:11 GMT
… in the Division of Cancer Medicine at The University … cancer setting, where patients often face limited effective treatments … -established that mTOR inhibitor everolimus [Afinitor] can work … phase 3 monarchE trial [NCT03155997] trial looking at endocrine …
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Investornewsbreaks Oncotelic Therapeutics, Inc. (OTCQB: OTLC) Joint Venture Sapu Nano Receives Approval To Begin Phase 1 Trial Of Injectable Everolimus For Breast Cancer
25 Sep 2025 06:47 GMT
… venture through GMP Biotechnology Limited, Sapu Nano … trial of Sapu003, an injectable form of Everolimus for breast cancer. Everolimus … , marketed as Afinitor(R), is FDA … , allowing full drug absorption into the …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
25 Sep 2025 00:11 GMT
… trial of Sapu003—an injectable form of Everolimus—for the treatment of breast cancer … through GMP Biotechnology Limited, … Everolimus is an FDA-approved drug (Afinitor®) for various cancers, including advanced breast cancer, kidney cancer … the medicine at …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
25 Sep 2025 00:00 GMT
… trial of Sapu003—an injectable form of Everolimus—for the treatment of breast cancer … through GMP Biotechnology Limited, … Everolimus is an FDA-approved drug (Afinitor®) for various cancers, including advanced breast cancer, kidney cancer … the medicine at …
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Sapu Nano’s Sapu003 Advances to Human Clinical Testing - Transforming Everolimus Delivery with Full Bioavailability for Breast Cancer Patients
24 Sep 2025 12:30 GMT
… trial of Sapu003—an injectable form of Everolimus—for the treatment of breast cancer … , formed through GMP Biotechnology Limited, a joint … Limited. Everolimus is already an FDA-approved drug (sold … in larger, controlled trials; regulatory developments in …
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<![CDATA[Giredestrant + Everolimus Delivers New Hope in ER+ Breast Cancer Post-CDK4/6 Treatment]]>
24 Sep 2025 00:43 GMT
… adverse effects of everolimus and SERD treatments, and there were … about 70% of breast cancer cases. Treatment with aromatase inhibitors, … condition, the history of drug tolerance, and other diseases … ease of taking the medicine orally.
REFERENCES
Positive phase …
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<![CDATA[Giredestrant Improves Survival in ER+, HER2– Breast Cancer]]>
23 Sep 2025 18:50 GMT
… novel agent giredestrant plus everolimus for the treatment of estrogen receptor (ER … be presented at an upcoming medical meeting and shared with regulatory … Advanced or Metastatic Breast Cancer (evERA Breast Cancer). ClinicalTrials.gov. Updated August …
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Roche's oral SERD comes good in 2nd-line breast cancer trial
23 Sep 2025 12:32 GMT
… combination of giredestrant with everolimus improved progression-free survival … disappointing clinical results.
One drug in the class – Menarini … second-line treatment of this type of breast cancer, though … in lidERA, with both trials due to read out …