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Assessing Everolimus for Neurocognitive Symptoms in PTEN Syndrome
22 Dec 2025 19:48 GMT
… often seen in both cancerous and non-cancerous conditions. This inhibition can … differently to Everolimus treatment, thus highlighting the necessity of personalized medicine in addressing … need for more rigorous clinical trials. The sensitivity analysis is a …
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Developments in breast cancer: What’s new from SABCS 2025
22 Dec 2025 19:07 GMT
… to show elacestrant + everolimus (8.3 months) … cancer has one of the most successful precision medicine … breast cancer research, cytotoxic free regimens, first line treatment, … , metastatic breast cancer, palbociclib, PATINA trial, pertuzumab, progression …
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What's Next for Metastatic Breast Cancer Treatments? | SABCS 2025
18 Dec 2025 00:24 GMT
… trial support its potential use with the targeted therapy everolimus … FDA approved a combination of drugs as a new first treatment … both medicines extended time without cancer growth. While these drugs … effective the medication is. Talk with your doctor about …
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<![CDATA[Giredestrant/Everolimus Improves PFS Across Subgroups After CDK4/6i in ER+/HER2– Breast Cancer]]>
12 Dec 2025 21:41 GMT
… division chief of breast medical oncology and a professor … of medical oncology and therapeutics … inhibitor treatment who have hormone receptor–positive advanced breast cancer,” … Breast Cancer: A Phase III trial of giredestrant plus everolimus in …
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<![CDATA[Dr Mayer on Efficacy Findings With Giredestrant Plus Everolimus in ER+/HER2– Advanced Breast Cancer]]>
12 Dec 2025 23:12 GMT
… giredestrant plus everolimus.”
Erica L. Mayer, MD, MPH, a medical oncologist and … advanced or metastatic breast cancer.
The evERA trial met both coprimary end … , supporting the robustness of the treatment effect.
Mayer emphasized that the …
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Roche presents details on breast cancer pill giredestrant
12 Dec 2025 10:29 GMT
… was consistent with Everolimus. In the acelERA Phase II trial, the primary … III trials spanning early, locally advanced, and metastatic ER-positive breast cancer … , including combinations with Everolimus, CDK4/6 …
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<![CDATA[Elacestrant-Based Combinations Show Efficacy, Safety in ER+, HER2-Negative Breast Cancer ]]>
12 Dec 2025 03:28 GMT
… #47;2 ELEVATE trial (NCT05563220).1
Findings … cancer?
In January 2023, the FDA approved elacestrant for the treatment … were diarrhea (elacestrant/everolimus, n = 23; elacestrant … www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves …
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<![CDATA[Dr Rugo on Elacestrant-Based Combos in ER+/HER2– Locally Advanced or Metastatic Breast Cancer]]>
12 Dec 2025 03:28 GMT
… Breast Medical Oncology, and director of the Women’s Cancers … from the phase 2 ELEVATE trial (NCT05563220), an open- … toxicities of each partner drug. The most frequent adverse … fatigue, and metabolic abnormalities with everolimus; however, elacestrant did not …
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The PHERGuide study demonstrates the utility of circulating tumor DNA for the early detection and real-time monitoring of localized HER2+ breast cancer
11 Dec 2025 15:00 GMT
… is a Phase II trial evaluating the efficacy and … on cancer cells, and deruxtecan, a potent chemotherapeutic drug. This … a new treatment approach that combines elacestrant with everolimus in … comprehensive management of clinical trials, covering from the study …
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Roche’s Oral SERD Cuts Death Risk by 30% in Early-Stage Breast Cancer
11 Dec 2025 14:12 GMT
… cancer or died, according to reporting by Fierce Biotech. … health authorities, Chief Medical Officer Levi Garraway said … standard endocrine therapy plus everolimus. Results released in … metastatic breast cancer. The trial combines the SERD pill with Pfizer …