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OncLive’s FDA Approval Report: The Regulatory Rundown for May 2025
31 May 2025 02:11 GMT
… This is the first FDA-approved treatment for LGSOC, addressing a … of trials examining avutometinib plus defactinib and excitement antibody-drug … vedotin was paired with erlotinib (Tarceva), it led … letter to Incyte Corporation stating that it could not …
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Phase 1/2 Trial Investigating ATR-04 for EGFRi-Related Rashes in Lung Cancer
28 May 2025 22:23 GMT
… 1/2 clinical trial of ATR04-484, we … the FDA for ATR04-484 in the treatment of … rash associated with EGFR inhibitors.
Dr. Mary Spellman, chief medical … including drugs like Erbitux (cetuximab), Vectibix (panitumumab), Tarceva (erlotinib) and …
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NeoGenomics Launches c-MET CDx Assay to Guide Treatment Decisions for Advanced Non-Small Cell Lung Cancer
22 May 2025 11:20 GMT
… U.S. Food and Drug Administration (FDA).*
“Accurate and timely … treatment,” said Dr. Nathan Montgomery, Vice President of Medical … , academic centers, and pharmaceutical firms with innovative diagnostic … Vedotin in Combination With Erlotinib in Patients With …
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Can Clinical Trials Negate Patentability for Pharma Inventions?
29 Apr 2025 17:24 GMT
… treatment against the standard treatment to secure FDA approval.
Clinical trials … . v. Sunovion Pharmaceuticals, Inc., the … doctors. But, critically, (i) the patients did not know the specific drug … Trial and Appeal Board’s holding of obviousness, stating …
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Scalp Pustule as a Manifestation of Erlotinib-Induced Skin Toxicity: Report of Two Cases and Literature Review
28 Apr 2025 17:19 GMT
… rash after EGFRI treatment (primarily with cetuximab and erlotinib). Early symptoms were … impact patients’ medication adherence, and high doses of therapeutic drugs may lead … S, et al. Randomized controlled trial on the skin toxicity of …
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Lactylation Score May Predict Bladder Cancer Treatment Outcome
24 Apr 2025 22:00 GMT
… efficacy of immune checkpoint inhibitor treatment, according to researchers.
Lactylation … MD, PhD, of Biruni University Medical School, Istanbul, Turkey, and colleagues … agents (sunitinib, pazopanib, gefitinib, erlotinib, and tipifarnib).
Future Impact
“All …
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A Pharmacist’s Guide to Lung Cancer and Its Key Treatments
23 Apr 2025 17:13 GMT
… the LUX-Lung trials and erlotinib benefiting patients after … in the CheckMate 227 trial.10 Together, these … skin rashes. Immune-based drugs can trigger inflammation in … treatments advance, targeted therapies are shifting care toward personalized medicine. …
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1L Treatment for Advanced NSCLC
15 Apr 2025 14:15 GMT
… .
Afatinib and erlotinib are also used as 1L treatments but are less … TKIs.
Safety Considerations for 1L Treatment: When selecting 1L therapies forEGFR … .
Drug interactions: EGFR TKIs, particularly erlotinib and afatinib, may interact with certain medications …
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From Plant Based Therapy to Plant-Derived Vesicle-Like Nanoparticles for Cancer Treatment: Past, Present and Future
17 Mar 2025 17:20 GMT
… oxidative stress. For example, Erlotinib and Imatinib induce ROS- … of targeted exosomes. Nat Biotechnol. 2011;29(4):341 … mechanism of traditional Chinese medicine in treatment of lung cancer. Chinese … and loaded with curcumin. Pharmaceutics. 2023;15(2):333. …
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The Role of Radiosensitizing Drugs in Osteosarcoma Treatment: Mechanisms and Clinical Perspectives
13 Mar 2025 15:57 GMT
… Preclinical Drug Trial Record Table
Table 2 Clinical Trials of Drugs … treatment.
Erlotinib was first approved by the Food and Drug … to Panpan Huang), Gannan Medical University start-up funds … F, et al. FDA drug approval summary: erlotinib (Tarceva) tablets. …