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CRISPR Therapeutics CRISPR Therapy Shows 90% Response Rate In Aggressive Blood Cancer
22 Dec 2025 18:55 GMT
… over the first month of treatment, with repopulating B-cells … at the Day 28 assessment.
Treatment has been well-tolerated, … of lymphodepletion with fludarabine and cyclophosphamide.
A total of 39 … autoimmune basket trials.
The Phase 1/2 clinical trial in …
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Imviva Biotech Announces First Patient Dosed in Phase 1b/2 TENACITY-01 Trial of CTD402 CAR-T Cell Therapy
22 Dec 2025 13:30 GMT
… MD, PhD, Imviva Biotech Chief Medical Officer. “The successful … lymphodepletion (fludarabine/cyclophosphamide) and a flat dose … clinical trial (TENACITY-01) evaluating CTD402 for the treatment … therapies for patients with cancer and autoimmune diseases. …
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FDA Approves Genentech’s Lunsumio VELO™ for Subcutaneous Use in Relapsed or Refractory Follicular Lymphoma
22 Dec 2025 06:30 GMT
… get the medicine their doctor prescribed. For … binds to cancer cells such as … medicines (a rituximab product, cyclophosphamide, doxorubicin, and prednisone) as a first treatment … : HEALTH FDA CLINICAL TRIALS RESEARCH SCIENCE PHARMACEUTICAL BIOTECHNOLOGY
SOURCE: …
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<![CDATA[Emerging Data Push Antibody-Drug Conjugates Into Earlier Lines of Therapy in DLBCL ]]>
19 Dec 2025 19:17 GMT
… Medical College of Wisconsin in Milwaukee.
LOTIS-7 Trial Design
Emerging trials … Dana-Farber Cancer Institute in … trial (NCT03274492) evaluated a modified regimen of rituximab (Rituxan), cyclophosphamide … drug conjugate loncastuximab tesirine for the treatment …
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<![CDATA[All Respond to BCMA/CD19 CAR T-Cell Therapy in NDMM Trials]]>
19 Dec 2025 18:59 GMT
… Changzheng Hospital of the Naval Medical University in China.
How … #47;m2 per day and cyclophosphamide at 300 mg/m2 … primary end point in both trials. Secondary end points included … , respectively.
The most common treatment-emergent adverse effects in the …
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A Multi-Country Study of the Clinical Course of Extensive-Stage Small Cell Lung Cancer: A Six-Study Analysis of Real-World Treatment Patterns and Outcomes
19 Dec 2025 14:01 GMT
… trial or treatment with an investigational study drug, … topotecan; lurbinectedin; taxane; cyclophosphamide, doxorubicin, and vincristine … Agency for Medicines and Medical Devices (ClinicalTrials … National Cancer Institute. Small cell lung cancer treatment ( …
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Positive Clinical Results from Phase 2 Trial of SGX945 for the Treatment of Behçet's Disease Published in Rheumatology (Oxford)
19 Dec 2025 09:44 GMT
… trial in aphthous ulcers of Behçet's Disease, enabling the medical … Drug designation for the treatment of Behçet's Disease by the FDA … drugs (e.g., cyclosporine or cyclophosphamide). These drugs … clinical trials of therapeutics and vaccines, obtaining …
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Hansa falls short in bid to push EU-approved kidney transplant drug into new autoimmune indication
17 Dec 2025 22:56 GMT
… phase 3 trial of its kidney transplant drug imlifidase—which … in previous anti-GBM trials, it did not show … plasma exchange (PLEX) combined with cyclophosphamide (CYC) and glucocorticoids.
“ … name for the treatment is Idefirix.
The medication is also approved …
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CRISPR Therapeutics Provides Broad Update on Zugocaptagene Geleucel (Zugo-cel; formerly CTX112™) in Autoimmune Diseases and Hematologic Malignancies
22 Dec 2025 13:30 GMT
… the first month of treatment, with repopulating B- … lymphodepletion with fludarabine and cyclophosphamide. A total of 39 … basket trials.
The Phase 1/2 clinical trial in … biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is …
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Study Finds Stem Cell Transplants Safe With Mismatched, Unrelated Donors
19 Dec 2025 23:13 GMT
… access to life-saving treatment—particularly for patients from … Jimenez, associate professor of medicine in the Division of … based on post-transplant cyclophosphamide (PTCy). This approach … .
The trial enrolled 268 adults with blood cancers who received …
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