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<![CDATA[Emerging Data Push Antibody-Drug Conjugates Into Earlier Lines of Therapy in DLBCL ]]>
19 Dec 2025 19:17 GMT
… Medical College of Wisconsin in Milwaukee.
LOTIS-7 Trial Design
Emerging trials … Dana-Farber Cancer Institute in … trial (NCT03274492) evaluated a modified regimen of rituximab (Rituxan), cyclophosphamide … drug conjugate loncastuximab tesirine for the treatment …
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<![CDATA[All Respond to BCMA/CD19 CAR T-Cell Therapy in NDMM Trials]]>
19 Dec 2025 18:59 GMT
… Changzheng Hospital of the Naval Medical University in China.
How … #47;m2 per day and cyclophosphamide at 300 mg/m2 … primary end point in both trials. Secondary end points included … , respectively.
The most common treatment-emergent adverse effects in the …
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A Multi-Country Study of the Clinical Course of Extensive-Stage Small Cell Lung Cancer: A Six-Study Analysis of Real-World Treatment Patterns and Outcomes
19 Dec 2025 14:01 GMT
… trial or treatment with an investigational study drug, … topotecan; lurbinectedin; taxane; cyclophosphamide, doxorubicin, and vincristine … Agency for Medicines and Medical Devices (ClinicalTrials … National Cancer Institute. Small cell lung cancer treatment ( …
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Positive Clinical Results from Phase 2 Trial of SGX945 for the Treatment of Behçet's Disease Published in Rheumatology (Oxford)
19 Dec 2025 09:44 GMT
… trial in aphthous ulcers of Behçet's Disease, enabling the medical … Drug designation for the treatment of Behçet's Disease by the FDA … drugs (e.g., cyclosporine or cyclophosphamide). These drugs … clinical trials of therapeutics and vaccines, obtaining …
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Hansa falls short in bid to push EU-approved kidney transplant drug into new autoimmune indication
17 Dec 2025 22:56 GMT
… phase 3 trial of its kidney transplant drug imlifidase—which … in previous anti-GBM trials, it did not show … plasma exchange (PLEX) combined with cyclophosphamide (CYC) and glucocorticoids.
“ … name for the treatment is Idefirix.
The medication is also approved …
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Study Finds Stem Cell Transplants Safe With Mismatched, Unrelated Donors
19 Dec 2025 23:13 GMT
… access to life-saving treatment—particularly for patients from … Jimenez, associate professor of medicine in the Division of … based on post-transplant cyclophosphamide (PTCy). This approach … .
The trial enrolled 268 adults with blood cancers who received …
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<![CDATA[Time to Progression a Key Prognostic Indicator in R/R DLBCL]]>
20 Dec 2025 08:17 GMT
… published in Therapeutic Advances in Medical Oncology.1
About two-thirds … (Rituxan; Genentech and Biogen) plus cyclophosphamide, doxorubicin, vincristine, and prednisone, the … response (CR),” they wrote. Subsequent treatments tend to be ineffective, they …
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Man presents with chronic dull pain in left eye
19 Dec 2025 18:34 GMT
… His medical history included tuberculosis (status post treatment), gout … mofetil, azathioprine and cyclophosphamide, which are indicated … immunosuppression, patients can trial anti-TNF agents … recruiting trials, guidelines
Clinical Guidance, Healio CME, FDA …
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Relapse Predictors of Idiopathic Retroperitoneal Fibrosis: A Long-Term Cohort Study
19 Dec 2025 14:01 GMT
… only randomized controlled trial to date further … medical history (symptoms, comorbid conditions, smoking, and treatment), … third reviewer.
Treatment
Clinical treatment for IRF patients … drugs in dual or triple regimens. Traditional IM included cyclophosphamide …
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<![CDATA[Fixed-Duration Epcoritamab Plus R-CHOP Provides Durable Remissions in First-Line DLBCL ]]>
18 Dec 2025 19:52 GMT
… (rituximab [Rituxan] plus cyclophosphamide, doxorubicin, vincristine, and prednisone … Falchi, MD, a medical oncologist and hematologist and … at Memorial Sloan Kettering Cancer Center, in New … the study authors wrote. Treatment-emergent adverse effects (TEAES …