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Advances and Challenges in Nano-Delivery Systems for Glioblastoma Treatment: A Comprehensive Review
04 Aug 2025 11:04 GMT
… -responsive drug release (eg, pH/enzyme-triggered), … hydrophobic drugs, with documented success in delivering COX-2 inhibitor celecoxib … . Artif Cells Nanomed Biotechnol. 2020;48(1 … photothermal-chemotherapy treatment of glioblastoma. J Pharmaceut Sci. 2025 …
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The Effects of Disease-Modifying Antirheumatic Drugs on Cardiovascular Risk in Inflammatory Joint Diseases: Current Evidence and Uncertainties
04 Aug 2025 05:52 GMT
… in treatment strategies. Preventive measures, including lifestyle changes, statins, and … selective and COX-2 selective inhibitors, are commonly used for pain management … for JAK inhibitors that treat certain chronic inflammatory conditions. FDA Drug Safety …
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Machine Learning Predicts Lipid Lowering Potential in FDA Approved Drugs
30 Jul 2025 16:54 GMT
… lipid‑lowering medications.
Screening of existing drugs using multi‑ … 430 FDA‑approved compounds (176 known lipid‑lowering drugs … prasterone engaged RXRα and COX‑2; Promega associated with MTP … humans. Randomized controlled trials and biochemical studies are …
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Stop pain, prevent injury and extend workouts
29 Jul 2025 14:12 GMT
… standard pain relievers or as a stand-alone medicine. … enzyme is an excellent partner nutrient to PEA. Serratiopeptidase binds to COX-2 … and researcher on effective treatment for fibromyalgia and … into the therapeutic applications. Biotechnol Rep (Amst). 2020; …
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Electroacupuncture and Parecoxib Reduce Inflammatory Injury in a Primary Dysmenorrhea Rat Model: Investigating the Role of the COX-2/NF-κB/NLRP3 Pathway
15 Jul 2025 21:37 GMT
… H20023250, Shandong Qidu Pharmaceutical Co., Shandong, China … from Beijing Huafukang Biotechnology Co., Ltd. … COX-2 may ameliorate PDM. Parecoxib sodium, a COX-2 inhibitor … treatment option for menstrual pain and an alternative to exclusive treatment with drugs …
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Immunomodulatory Activities of Thai Herbs and the Druggability of Their Bioactive Constituents: A Comprehensive Review for Potential Phytopharmaceutical Product Development
24 Jul 2025 22:47 GMT
… 19, Coronavirus Disease 2019; COX-2, Cyclooxygenase-2; ERK, … remedial panacea for designing and developing effective drugs and medicines: … suppresses plasminogen activator inhibitor-1-mediated macrophage … in healthy participants. Pharmaceuticals. 2024;17(12): …
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Addressing Pain in Oral Mucositis: Narrative Review of Current Practices and Emerging Treatments
23 Jul 2025 19:59 GMT
… pain from chemoradiation-induced OM, clinical trials of COX-2 inhibitors … pain often requires alternative therapies. In these cases medications like duloxetine (an antidepressant … of lytic enzymes.50
A … treatment option for radiation-induced mucositis. Drug …
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Axsome Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Update
04 Aug 2025 11:00 GMT
… absorbed, multi-mechanistic, selective COX-2 inhibitor and 5-HT1B… commercial and government (Medicare and Medicaid) channels are currently … treatment of narcolepsy. AXS-12 has been granted FDA Orphan Drug … long-term safety trial. Across these trials, AXS-12 …
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Best CBD Creams for Pain Relief: Top Picks for Joints & Muscle Aches
16 Jul 2025 21:42 GMT
… great alternative to traditional pain medicines, especially if you’ … of nerve pain) in people undergoing cancer treatment [11].
… through inhibition of iNOS, COX-2, and cytokines via … the lower extremities. Current Pharmaceutical Biotechnology, 21(5), 390–402 …
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As Korea enters super-aged society, gastrointestinal protection is now a treatment strategy
15 Jul 2025 10:01 GMT
… by inhibiting the enzymes COX-1 and COX-2, which are … and replace them with COX-2 selective inhibitors whenever possible.
“NSAIDs … either curative or prophylactic treatment,” Choi pointed out.
… other criteria for drug selection in the medical field.
…