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KEYTRUDA® (pembrolizumab) and KEYTRUDA QLEX™ (pembrolizumab and berahyaluronidase alfa-pmph), Plus Paclitaxel ± Bevacizumab, Approved for Certain Adults with PD-L1+ (CPS ≥1) Platinum-Resistant Ovarian Carcinoma as Second or Third Line Treatment
11 Feb 2026 17:30 GMT
… in metastatic non–small cell lung cancer (NSCLC), serious adverse … in combination with platinum (cisplatin or carboplatin) and FU … resection.
Non-Small Cell Lung Cancer
KEYTRUDA and KEYTRUDA QLEX … nonsquamous non–small cell lung cancer (NSCLC), with no …
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A Prognostic Nomogram Combining Radiologic Emphysema and Clinical Parameters in Small Cell Lung Cancer
27 Jan 2026 21:30 GMT
… lung cancer (SCLC) represents a distinct subtype of lung cancer characterized … approximately 15% of all lung cancers worldwide, is closely … n = 14), irinotecan plus cisplatin (n = 12), and … cell lung cancer; OS, overall survival; SCLC, small cell lung cancer; …
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Inflammation: The Pathological Axis of Cisplatin-Induced Renal Injury
29 Jan 2026 12:42 GMT
… based compounds, including cisplatin. Evidence indicates … transporters significantly decreases cisplatin accumulation and toxicity … contributing to cisplatin-induced nephrotoxicity.
Cisplatin-Triggered Inflammation– … kidney injury in lung cancer. Inflamm Res. …
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Phytochemical and Anti-Ischemic Stroke Properties from the Vitex L. Genus
10 Feb 2026 22:10 GMT
… and mitochondria permeability transition in lung cancer cells. Biomedicines. 2024;12(3 … -apoptotic effects of vitexilactone on cisplatin-induced nephrotoxicity in rats. Biotech …
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Evodiamine Targets Genes in Cisplatin-Resistant Lung Cancer
11 Dec 2025 08:45 GMT
… against cisplatin-resistant non-small cell lung cancer (NSCLC). Cisplatin, … significant fraction of lung cancer cases globally, … in oncologycisplatin-resistant lung cancer treatmentdifferential gene … therapynon-small cell lung cancer researchovercoming drug …
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Bixin Beyond Colour: Expanding Therapeutic Horizons Through the Integration of Pharmacological Potential with Modern Drug Design and Delivery Strategies
10 Feb 2026 12:13 GMT
… preventive strategy against CRC. In lung cancer models, Nurcahyanti et al34 explored … dual carotenoid therapy selectively sensitized cisplatin-resistant A549 and HeLa … fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro …
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Cisplatin Boosts Lung Cancer Stem Cells via NF-κB
22 Nov 2025 02:51 GMT
… various cancers, including lung cancer. However, its clinical … to develop lung tumors, exposure to cisplatin resulted in … cells, NF-κB, cisplatin, lung cancer, DNA repair pathways, chemotherapy … lung cancerCisplatin and lung cancer treatmentcisplatin and tumor …
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Korean team identifies ‘resistance switch’ in KRAS-mutated lung cancer
16 Dec 2025 06:48 GMT
… drive drug resistance in lung cancer.
Professor Shin Dong-hoon … of anticancer drugs in lung cancers harboring KRAS mutations. The … develops in KRAS-mutated lung cancer.
KRAS mutations are common … agents used in NSCLC—cisplatin and pemetrexed—the compound …
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Hypoxia-Induced Autophagy Drives Lung Cancer Drug Resistance
12 Dec 2025 03:16 GMT
… of drug resistance in lung cancer treatment, researchers have … modulates cisplatin resistance in non-small cell lung cancer (NSCLC …
Non-small cell lung cancer remains a leading cause … autophagynon-small cell lung cancer treatmentnovel therapeutic approaches …
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Regionals at the Rotunda: Alexis Evans and C.J. Johnston
09 Feb 2026 22:29 GMT
… responsiveness varies greatly. Most lung cancer patients continue to receive … various drugs like paclitaxel, cisplatin, and doxorubicin. Using … involves engineering human lung cancer cells to explore … involves engineering human lung cancer cells to explore …
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