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Bayer’s experimental blood-thinner notches trial win in stroke prevention
25 Nov 2025 04:12 GMT
… along with standard treatments. The trial compared treatment with a combination … prevention, doctors use one or two drugs to thin … medications. The drugs used include aspirin, clopidogrel, AstraZeneca’s Brilinta … milvexian’s Phase 3 trials in people with …
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Mapping lipid pockets to drug the undruggable proteome
24 Nov 2025 09:01 GMT
… /II clinical trial for advanced solid tumours … Outlook: from mechanism to medicine
Auto-palmitoylation research illustrates … years’ experience in drug discovery, translational science … contributing to therapies including Brilinta, Symbicort and Keytruda.
…
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Alembic Pharmaceuticals receives US FDA final approval for ticagrelor tablets, 60 mg
29 Oct 2025 10:05 GMT
… Food & Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) ticagrelor … reference listed drug (RLD), Brilinta tablets, 60 mg, of AstraZeneca Pharmaceuticals LP (AstraZeneca … who have been stented for treatment of ACS; to reduce the …
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Integrity Concerns in Ticagrelor Trials Challenge Clinical Confidence
07 Jul 2025 14:05 GMT
… emerged over the trial data supporting ticagrelor (Brilinta; AstraZeneca), … FDA, despite being included in the published versions of the trials … when the drug is discontinued.
“If doctors had known … and Counseling
As trusted medication experts, pharmacists are …
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Scientists Uncover New Concerns About Billion-Dollar Heart Drug
29 Jun 2025 17:16 GMT
… the FDA.
For over ten years, ticagrelor (sold as Brilinta in … the trials were not present in US Food and Drug Administration (FDA) … was not involved in the trial, and most investigators, including … . If doctors had known what happened in these trials, they …
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CytoSorbents Files Request For Supervisory Review For DrugSorb-ATR Device
24 Jun 2025 16:47 GMT
… with the U.S. FDA of the De Novo Denial … days of stopping the antiplatelet drug Brilinta. The company determined that a … directly and effectively with senior FDA leadership connecting them with the … , who can provide the FDA with critical insight and expert …
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AstraZeneca faces new allegations over trial data for blood thinner Brilinta: BMJ
23 Jun 2025 18:57 GMT
… , the U.K. medical journal BMJ found data integrity … used in the trials were eliminated from FDA datasets, the … -platelet drug.”
The BMJ also found that one trial investigator … huge investment in Brilinta after its blockbuster statin treatment Crestor lost …
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Top medics issue urgent warning over heart drug taken by millions - as makers AstraZeneca are accused of 'misreporting' safety data
20 Jun 2025 00:14 GMT
… , top doctors have warned.
Anti-clotting pill ticagrelor was … whether a treatment is effective—for both trials were inaccurately … US medicine';s regulator, the Food and Drug Administration (FDA) used … .
The twice-daily pill, sold as Brilinta, is given to …
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BMJ investigation raises new concerns over ticagrelor approval trials
21 Jun 2025 13:19 GMT
… its FDA approval.
For more than a decade, ticagrelor (Brilinta … the trials were not present in US Food and Drug Administration (FDA) … not involved in the trial, and most investigators, including … bleeding. If doctors had known what happened in these trials, they …
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AstraZeneca’s deadly deception: Heart drug Brilinta exposed as ineffective, increasing heart attack risks
20 Jun 2025 21:27 GMT
… push a dangerous drug. The company’s COVID-19 vaccine was linked … Brilinta’s trial data. "If doctors had known what happened in these trials … rubber-stamping dangerous drugs under pressure from pharmaceutical lobbyists. Brilinta’s approval followed …