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DESTINY-Breast09 Data Spark Debate on Sequencing and Frontline Maintenance Strategies in HER2+ Breast Cancer
17 Jul 2025 22:29 GMT
… patients with metastatic HER2-positive breast cancer. It specifically enrolled patients … receptor–positive, HER2-positive metastatic breast cancer]. There are other trials … trial [NCT02614794] regimen with capecitabine [Xeloda] plus tucatinib [Tukysa] and …
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Dr Hamilton on Unmet Needs for Brain Metastases in HER2+ Metastatic Breast Cancer
17 Jul 2025 22:28 GMT
… patients with HER2-positive metastatic breast cancer.
Although unmet needs remain … (Xeloda) for the treatment of patients with HER2-positive metastatic breast cancer who … older with advanced HER2-positive breast cancer; had previously received trastuzumab, …
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What You Need to Know About Breast Cancer Chemotherapy Pills
01 Jul 2025 14:46 GMT
… available for the treatment of breast cancer:
Monoclonal antibodies: These … receptor 2 (HER2) positive breast cancer. These medications are typically … treatment of advanced HER2-positive breast cancer.
Capecitabine (Xeloda) and cyclophosphamide (Cytoxan) …
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Yan Emphasizes Use of Supportive Care With Dato-DXd in Breast Cancer
27 Jun 2025 00:28 GMT
… to chemotherapy in pretreated metastatic breast cancer. While relatively tolerable, they each … -generation sequencing)
Second line: capecitabine (Xeloda) for 10 months
Now, MRI … , HER2-negative (HR+/HER2–) breast cancer (BC): final overall survival (OS …
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Zanidatamab Plus Chemotherapy Shows Promising Anti-Tumor Activity in Treatment of HER2-Mutated Breast Cancer
21 May 2025 23:08 GMT
… (HER2)-mutated metastatic breast cancer (mBC). The data … for Medical Oncology Breast Cancer 2025 Annual Meeting … Bristol Myers Squibb], capecitabine [Xeloda; Genetech, Roche], or vinorelbine … with HER2-mutated metastatic breast cancer, particularly those who …
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Zanidatamab/Chemotherapy Yields Responses and Is Safe in HER2-Expressing Metastatic Breast Cancer
16 May 2025 22:44 GMT
… patients with HER2-positive metastatic breast cancer who had previously received HER2 … advanced or metastatic HER2-expressing breast cancer with an ECOG performance status … ; n = 20), zanidatamab plus capecitabine (Xeloda; n = 19), or zanidatamab plus …
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T-DXd Improves All Outcomes in Post-Hoc Look of DESTINY-Breast06 in HR+, HER2-Low/-Ultralow Metastatic Breast Cancer
15 May 2025 21:24 GMT
… physician’s choice with capecitabine (Xeloda) or taxane (nab-paclitaxel [ … low or HER2-ultralow metastatic breast cancer, according to additional data from … identify patients with HER2-ultralow breast cancer.
Additional Trial Objectives, Findings, and …
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Pyrotinib-Based Therapy May Improve Survival in Patients With HER2+ Breast Cancer and Liver Metastases
25 Apr 2025 15:47 GMT
… (HER2+) advanced metastatic breast cancer (mBC) with liver … in combination with capecitabine (Xeloda; Genentech) for advanced … positive liver metastatic advanced breast cancer. Front Oncol. April … for HER2-positive metastatic breast cancer: a systematic review …
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Tucatinib and Trastuzumab Demonstrates Safety, Efficacy in HER2-Mutated Breast Cancer
17 Apr 2025 15:43 GMT
… receptor 2 (HER2)-mutated breast cancer (BC). The data … when used with capecitabine (Xeloda; Genentech) for patients with … in HER2-mutated metastatic breast cancer: a phase 2 basket … patients with advanced HER2+ breast cancer (HER2CLIMB). Updated August 14 …
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Advancing Care for Metastatic Breast Cancer: Oncology Pharmacists Tackle Innovation, Biomarkers, and Operational Hurdles
28 Feb 2025 20:40 GMT
… in ESR1-mutated metastatic breast cancer (MBC) management, biomarker … biomarker testing recommendations for breast cancer, but they currently … patients with advanced breast cancer with ESR1 mutations, … , such as capecitabine (Xeloda; Genentech, Inc), might …