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New approach shields memory from brain cancer radiotherapy
16 Oct 2025 10:19 GMT
… standard of care for brain cancers that often causes irreversible … and mice implanted with brain tumors (glioblastoma and astrocytoma cell … mice with and without brain cancer,” said Robert Krattli, … models and patient-derived xenografts,” Acharya said. “These …
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Saikosaponin D Induced Apoptosis and Anti-Tumor Effect Enhancing Chemotherapy Sensitivity of Gemcitabine in Patient-Derived Cholangiocarcinoma Organoids
21 Jan 2026 22:55 GMT
… : (1) using patient-derived organoid xenograft (PDOX) models to assess in … . Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 2018;15 …
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Targeting Nuclear Receptors: A New Frontier in Brain Cancer Therapy
16 Sep 2025 14:43 GMT
… employing patient-derived xenografts and immunocompetent models … distinguish and drive diverse brain tumor phenotypes. The integration … in brain cancer therapysurgical and radiotherapy advancementstherapeutic intervention for brain tumorstranscription …
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Filamentous Phage for Therapeutic Applications in Non-Small Cell Lung Cancer and Brain Metastases: Recent Prospect
19 Jan 2026 18:47 GMT
… image pancreatic cancer xenografts via fluorescence microscopy … cell culture or animal xenografts. Collectively, these … increased gefitinib concentration in brain tumors.
Similarly, T790M … platform for targeting malignant brain tumors. Biomaterials. 2020;252 …
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Focused Ultrasound-Mediated Temozolomide Delivery Into Intact Blood-Brain Barrier Tissue Improves Survival in Patient-Derived Xenograft Model of Glioblastoma
28 Aug 2025 10:36 GMT
… most prevalent and aggressive primary brain tumor in adults, characterized by rapid … and survival in an orthotopic xenograft mouse model.
MethodsHuman primary GBM … mice to establish an orthotopic xenograft model. FUS was applied 1 …
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Brain tumors exploit body's daily rhythms to fuel growth
18 Dec 2024 15:43 GMT
… most common and aggressive malignant brain tumor in adults, with limited survival … in vivo experiments involved orthotopic xenografts, in which human and mouse …
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Small brain-penetrating molecule offers hope for treating aggressive brain tumors
21 Nov 2024 12:28 GMT
… glioblastoma, an aggressive form of brain tumor.
The study found that gliadin … the most lethal forms of brain cancer and is known for its … cell lines and patient-derived xenograft models. Additionally, the pharmacokinetic studies …
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HDAC1 Condensation Links to Temozolomide Response in Glioblastoma
10 Jan 2026 12:24 GMT
… most aggressive forms of brain cancer, the standard therapy temozolomide … results from patient-derived xenograft models substantiate this approach, … Tags: acquired resistance in brain tumorsbrain cancer therapeutic advancementschromatin accessibility …
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Sylvester Brain Tumor Institute Launches to Personalize Brain Cancer Treatment
15 May 2024 06:56 GMT
… of the Sylvester Brain Tumor Institute (SBTI) to elevate brain cancer care and research … in South Florida and beyond.
“The Sylvester Brain Tumor … cancer cells, and patient-derived xenografts, where tumor cells are re …
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Sylvester Cancer Launches New Brain Tumor Institute to Personalize Brain Cancer Treatment
09 May 2024 14:17 GMT
… , personalized care for brain cancer patients.
“The Sylvester Brain Tumor Institute will further enable … cancer cells, and patient-derived xenografts, where tumor cells are re … using patient-derived organoids and xenografts, those efforts will be bolstered …