-
Alphamab Oncology Announces IND Application for a Phase II Clinical Study of HER2 Bispecific ADC Subcutaneous Co-formulation JSKN033 as First-line Treatment of Advanced Cervical Cancer was Officially Accepted by CDE
29 Dec 2025 09:18 GMT
… with or without bevacizumab as first-line treatment of advanced … Center for Drug Evaluation (CDE) of the National Medical Products … multicenter phase II clinical trial designed to evaluate the … ;II clinical trials of JSKN033 for the treatment of solid …
-
Adding antibody treatment to chemo boosts outcomes for children with rare cancer: Study
25 Dec 2025 19:36 GMT
… treatment to usual chemotherapy, according to new results from a clinical trial … Cancer Research UK Clinical Trials Unit. Published in the … Cancer Research UK Clinical Trials Unit at the … an anti-tumour drug bevacizumab with chemotherapy drugs led to patient …
-
FDA approves Nufymco as biosimilar to Lucentis
24 Dec 2025 18:43 GMT
… patient access to expensive biologic drugs and reducing health care system … ’ branded Avastin, Lytenava (bevacizumab-vikg), is undergoing additional FDA review, with a … Vitreous Associates of Florida
Chief medical officer, Network Eye
Disclosures: Eichenbaum …
-
<![CDATA[JSKN003 Nets FDA Breakthrough Therapy Designation in Pretreated HER2+ Platinum-Resistant Ovarian Cancer]]>
23 Dec 2025 23:46 GMT
… who have received prior treatment with bevacizumab (Avastin).1
Findings … JSKN003-102 (NCT05744427) clinical trials supported the regulatory decision. … orphan drug designation from the FDA for the treatment of … 1/2 clinical trial, JSKN003 produced an ORR …
-
Twelve‑Month Response and Safety of Intravitreal Dexamethasone Implant in Treatment‑Naïve and Recalcitrant Diabetic Macular Edema (TREAT-DME Study)
23 Dec 2025 18:34 GMT
… medically controllable intraocular pressure (IOP) spikes.15–20 Despite strong trial … most DEX trials focused on treatment-naïve or mixed … following intravitreous aflibercept, bevacizumab, or ranibizumab for … Swiss cohort study. Pharmaceuticals. 2024;17(9): …
-
<![CDATA[The OncFive: Top Oncology Articles for the Week of 12/21]]>
27 Dec 2025 22:20 GMT
… England Journal of Medicine demonstrated that … drug conjugate JSKN003 received FDA breakthrough therapy designation for the treatment … have received prior treatment with bevacizumab (Avastin).
Findings … (NCT05744427) clinical trials supported the regulatory …
-
Top 5 Most-Read Ophthalmology Articles of 2025
26 Dec 2025 14:52 GMT
… (reference bevacizumab), was discontinued from Australia’s Pharmaceutical Benefits Scheme … effective for patients undergoing treatment for retinal conditions. … found no reported drug-related ocular or … by the FDA and the European Medicines Agency.
Read …
-
Outlook Therapeutics Announces New Employment Inducement Grants
26 Dec 2025 22:00 GMT
… standard of care for bevacizumab for the treatment of retina diseases, today … standard of care for bevacizumab for the treatment of retinal diseases. LYTENAVA … ™ (bevacizumab gamma) is the first ophthalmic …
-
<![CDATA[Botensilimab/Balstilimab Exhibits Meaningful Activity in Ovarian Cancer]]>
24 Dec 2025 20:28 GMT
… containing doublet chemotherapy (100%), bevacizumab (Avastin; 77%), PARP … Secondary end points included treatment-emergent adverse effects (TEAEs … trial. A total of 19 patients (43%) discontinued either treatment … ’Day, MD, chief medical officer of Agenus, the …
-
Clinical Practice and Survival Analysis of Third-Line Therapy in Patients with Metastatic Colorectal Cancer: A Single-Center Retrospective Study
27 Dec 2025 11:30 GMT
… afford the newer third-line drugs such as regorafenib, thus … MSI-H settings. Research from trials such as UNION, TORCH, … current standard third-line treatment, the medical community has been prompted … trial of TAS-102 plus bevacizumab as a third-line treatment …